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Thalitone
Swollen feet or ankles, Chronic Kidney Disease (CKD), Congestive Heart Failure + 5 more
Treatment
20 Active Studies for Thalitone
Treatment for
Swollen feet or ankles
What is Thalitone
ChlorthalidoneThe Generic name of this drug
Treatment SummaryChlorthalidone is a medication used to treat high blood pressure and swelling caused by heart or kidney problems. It works by preventing the kidneys from absorbing too much salt and water, which helps reduce blood pressure. Studies have shown that chlorthalidone can reduce the risk of stroke, heart attack, and even death in people with high blood pressure. It is often used as a first-line treatment for hypertension and may be more effective than other medications like beta-blockers, ACE inhibitors, calcium channel blockers, or ARBs. Chlorthalidone has also been shown to reduce platelet aggregation and increase vascular permeability
Chlorthalidoneis the brand name
Thalitone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Chlorthalidone
Chlorthalidone
1981
193
Effectiveness
How Thalitone works in the bodyChlorthalidone stops sodium and chloride from being reabsorbed back into the body. When this happens, fluid is forced out of the body, which lowers blood pressure. Chlorthalidone also helps reduce platelet aggregation and increases the formation of blood vessels, both of which help reduce the risk of cardiovascular disease.
When to interrupt dosage
The suggested measure of Thalitone is contingent upon the determined state, such as Cirrhosis, multiple antihypertensive drugs potentially needed and Swelling. The dosage may also differ according to the technique of delivery noted in the tabular presentation below.Condition
Dosage
Administration
Hypertensive disease
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Swollen feet or ankles
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Chronic Kidney Disease (CKD)
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
multiple antihypertensive drugs likely required
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Congestive Heart Failure
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
not adequately controlled with monotherapy
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Cirrhosis
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Nephrolithiasis
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Tablet - Oral, Tablet, Oral
Warnings
Thalitone has two prohibitions. If you suffer from any of the conditions in the table below, Thalitone should not be employed.Thalitone ContraindicationsCondition
Risk Level
Notes
Anuria
Do Not Combine
allergic reaction to sulfonamide derivatives
Do Not Combine
Common Thalitone Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Chlorthalidone may increase the hypotensive activities of Amifostine.
Cyclopentamine
Major
The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Cyclopentamine.
Dofetilide
Major
The risk or severity of QTc prolongation can be increased when Chlorthalidone is combined with Dofetilide.
Hexamethonium
Major
The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Hexamethonium.
Lithium carbonate
Major
Chlorthalidone may decrease the excretion rate of Lithium carbonate which could result in a higher serum level.
Thalitone Novel Uses: Which Conditions Have a Clinical Trial Featuring Thalitone?
641 active trials are presently being conducted to assess the effect of Thalitone in managing Kidney Disease, Cirrhosis and Hypertensive Diseases.Condition
Clinical Trials
Trial Phases
not adequately controlled with monotherapy
0 Actively Recruiting
Chronic Kidney Disease (CKD)
28 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4
Cirrhosis
53 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1
Congestive Heart Failure
187 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
multiple antihypertensive drugs likely required
0 Actively Recruiting
Hypertensive disease
28 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Swollen feet or ankles
5 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Nephrolithiasis
0 Actively Recruiting
Thalitone Reviews: What are patients saying about Thalitone?
5Patient Review
2/28/2020 I had some initial dizziness when starting this medication, but it quickly subsided and I haven't had any problems since. I've been taking it for almost four years now with no issues.
5Patient Review
2/28/2020 I had some dizziness when I started this medication, but it went away after a few weeks. I've been on the treatment for almost four years now and have had no problems.
5Patient Review
2/28/2020 I had some dizziness when I first started taking this medication, but it eventually went away and I've been taking it for nearly four years now with no problems.
4Patient Review
8/15/2018 This medicine was successful in lowering my blood pressure; however, the chest pain I experience as a side effect sent me to the hospital several times. The feeling is very uncomfortable and left me no choice but to discontinue use of the medication.
4Patient Review
6/4/2022 While this lowered my blood pressure as intended, the side effects were a bit hard to deal with. They included constipation, loss of appetite, and dizziness. The good news is that they improved over time.
4Patient Review
8/15/2018 Though this medication lowered my blood pressure, the chest pain I experienced as a side effect sent me to the hospital several times. It was so severe that I had to stop taking the medicine. In addition to the chest pain, I also felt face numbness on my left side whenever I took the medicine. While it may work for others, the side effects were enough for me to say no.
4Patient Review
6/4/2022 This treatment lowered my blood pressure, but the side effects were tough at first. I experienced constipation and a loss of appetite, as well as some dizziness. The lack of appetite caused weight loss, which was difficult to deal with. However, over time the side effects lessened and I was able to manage them better.
4Patient Review
8/15/2018 Though this medicine was great at lowering my blood pressure, the chest pain it caused sent me to the hospital multiple times. I had to discontinue use because of how severe the pain was; it felt tight and heavy. Additionally, I experienced left-sided facial numbness whenever I took the medicine. Though it may work for others, the side effects were enough for me to say no.
4Patient Review
6/4/2022 While this treatment effectively lowered my blood pressure, the side effects were a bit tough to manage at first. With time, though, they improved. I experienced constipation and loss of appetite for the most part and some dizziness too. The loss of appetite caused weight loss--even though I tried to eat anyway, it made me nauseous sometimes. All things considered, it's not a bad option.
3.7Patient Review
4/7/2019 So far, so good! My blood pressure is better than it's ever been. The only downside is that I have to go to the bathroom more often than usual.
3.7Patient Review
4/7/2019 So far, so good! My blood pressure has been great since starting this medication. Although, the constant urge to urinate is really getting on my nerves...
3.7Patient Review
4/7/2019 Even though I've only been on the medication for a short time, my blood pressure has never been better. Although, the constant need to urinate might be too much for some people. Otherwise, I'm good.
3Patient Review
9/11/2019 I developed some lightheadedness, muscle cramps, and jitters within a few weeks of taking 25mg per day. My BP also dropped quite low, so I consulted with my cardiologist and cut the dose in half. There was some improvement in the side effects, but not enough, so I stopped taking the medication altogether. So far my BP has remained in a good range (I'm also taking losartan and verapamil) and my IBS seems to be better too.
3Patient Review
8/29/2019 I experienced diarrhea soon after starting this medication, to the point where I couldn't leave my house or eat. After a few days of stopping the medication, though, the upset stomach cleared up.
3Patient Review
9/11/2019 Within a couple of weeks of taking 25 mg a day, I developed lightheadedness, muscle cramps and jitters, and very low blood pressure. I consulted my cardiologist and cut the daily dose in half. There was some improvement in side effects but not enough, so I stopped taking it altogether. My blood pressure has remained in good range for over a week (I also take losartan and verapamil - they seem to be more effective now!). I think this medication also exacerbated my irritable bowel syndrome with diarrhea, and caused stomach discomfort.
3Patient Review
8/29/2019 I had some initial success with this medication, but then I started having really bad diarrhea. After a few weeks of being housebound, I stopped taking the medication. Thankfully, my upset stomach cleared up soon after stopping the treatment.
3Patient Review
9/11/2019 I experienced some very unpleasant side effects after only a few weeks of taking this medication. These included lightheadedness, muscle cramps, jitters, and low blood pressure. I spoke to my cardiologist and we decided to halve the dose, which helped somewhat but not enough. So, I stopped taking the medication entirely and have been feeling better ever since.
3Patient Review
8/29/2019 I experienced some initial success with this treatment, but then I started having really bad diarrhea. After a few weeks of being housebound, I stopped taking the medication and fortunately my stomach issues resolved themselves shortly thereafter.
2.3Patient Review
6/11/2019 Chlorthalidone hospitalised me after just three days due to an extreme and rapid heart rate. While it was effective in lowering my blood pressure, the risks are not worth it for me. I would caution anyone taking this medication to be aware of potential heart issues.
2.3Patient Review
8/1/2019 I didn't have a good experience with this medication. It made me feel lightheaded and my heart rate was elevated, even when I wasn't doing anything physical. I stopped taking it right away.
2.3Patient Review
6/14/2018 I took this drug for thirty days but had to stop because the side effects were becoming too much. I would have sudden spells of breathlessness and pain in my upper chest, as well as lightheadedness when transitioning from a kneeling to standing position. Additionally, I experienced slight diarrhea. Overall, I would not recommend this medication to anyone.
2.3Patient Review
6/11/2019 Chlorthalidone sent me to the hospital after 3 days with extreme rapid heart rate upon just walking normally. It worked a bit to lower my blood pressure but anything that messes with the rhythm of my heart is a no go. If you take it, please look out for an elevated heart rate. I got blood work done and everything was in range but for some reason this medication messes with my heart rate which sucks.
2.3Patient Review
8/1/2019 I tried this medication twice and didn't react well to it either time. It made me feel lightheaded and my heart rate increased, even when I wasn't doing anything physical. So, I stopped taking it.
2.3Patient Review
6/14/2018 I took this medication for thirty days as prescribed. While my blood pressure improved, the side effects began to worsen to the point where I had to stop taking it. These included shortness of breath, pain in my upper chest, and almost passing out when going from a kneeling to standing position. I also experienced slight diarrhea. Overall, I would not recommend this drug to anyone.
2.3Patient Review
6/11/2019 Chlorthalidone gave me an extreme rapid heart rate after just a few days, which landed me in the hospital. It did lower my blood pressure some, but anything that messes with the rhythm of my heart is a no-go for me. If you take this medication, please be on the lookout for an elevated heart rate.
2.3Patient Review
8/1/2019 I didn't have a good experience with this medication. It made me feel dizzy and my heart rate was increased, even when I wasn't doing anything physical. So, I stopped taking it.
2.3Patient Review
6/14/2018 I took this medication for thirty days as prescribed. While my blood pressure normalized, the side effects got progressively worse to the point where I had to stop taking it. These included shortness of breath, pain in my upper chest, and almost fainting when going from a kneeling to standing position. Additionally, I experienced very slight diarrhea. Overall, I would not recommend this drug to anyone.
1Patient Review
8/25/2019 Unfortunately, this led to a hospital stay after just three days of use.
1Patient Review
8/25/2019 Unfortunately, this medication landed me in the hospital after just three days of use.
1Patient Review
8/25/2019 Unfortunately, this led to me being hospitalized after just three days of use.
1Patient Review
8/25/2019 Unfortunately, this treatment landed me in the hospital after just three days of use.
1Patient Review
8/25/2019 I had to go to the hospital after just three days of using this treatment.
1Patient Review
8/25/2019 Unfortunately, this treatment landed me in the hospital after just three days of use.
1Patient Review
8/25/2019 Unfortunately, this resulted in a hospital visit after just three days of use.
1Patient Review
8/25/2019 Unfortunately, this led to a hospital visit after just three days of use.
1Patient Review
8/25/2019 I had to go to the hospital after just three days of using this treatment.
Patient Q&A Section about thalitone
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Thalitone prescribed for?
"This can help to lower blood pressure.
Chlorthalidone is used to treat high blood pressure, which can help to prevent strokes, heart attacks, and kidney problems. It is also used to reduce extra salt and water in the body caused by conditions such as heart failure, liver disease, and kidney disease, which can help to lower blood pressure."
Answered by AI
Is Thalitone the same as chlorthalidone?
"Chlorthalidone is a diuretic, meaning it increases the amount of urine you make. This is especially true when you first start the medication. Chlorthalidone also helps relax the blood vessels, which allows blood to flow more easily. It is available under the brand names Hygroton, Thalitone, and Chlorthalid."
Answered by AI
What drug class is Thalitone?
"Thalitone can be used by itself or in combination with other drugs. It is a member of a class of medications known as diuretics, specifically thiazides."
Answered by AI
What is the side effects of chlorthalidone?
"These are all symptoms of a stomach virus."
Answered by AI
Clinical Trials for Thalitone
Have you considered Thalitone clinical trials? We made a collection of clinical trials featuring Thalitone, we think they might fit your search criteria.Go to Trials
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