Diovan

Hypesthesia, Hypesthesia, Hypesthesia + 15 more
Treatment
11 FDA approvals
20 Active Studies for Diovan

What is Diovan

ValsartanThe Generic name of this drug
Treatment SummaryValsartan is a medication that helps lower blood pressure and treats other conditions related to the heart. It is part of a family of drugs called angiotensin II receptor blockers (ARBs), which work by blocking the protein angiotensin II and preventing it from causing high blood pressure, increased cardiac activity, and other negative effects. Valsartan is used to treat hypertension, heart failure, and kidney problems in people with type 2 diabetes. It works by blocking the action of the renin-angiotensin aldosterone system (RAAS), which can reduce fluid retention and improve heart function. Vals
Diovanis the brand name
image of different drug pills on a surface
Diovan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Diovan
Valsartan
1996
621

Approved as Treatment by the FDA

Valsartan, also known as Diovan, is approved by the FDA for 11 uses such as Heart failure and High Blood Pressure .
Heart failure
Used to treat Heart Failure in combination with Sacubitril
High Blood Pressure
Used to treat Moderate Essential Hypertension in combination with Hydrochlorothiazide
chronic heart failure with reduced ejection fraction (NYHA Class II-IV)
Used to treat chronic heart failure with reduced ejection fraction (NYHA Class II-IV) in combination with Sacubitril
Heart Failure
Used to treat hospitalization due to cardiac failure in combination with Sacubitril
Systolic Left Ventricular Dysfunction
Used to treat Systolic Left Ventricular Dysfunction in combination with Sacubitril
Moderate Essential Hypertension
Used to treat Moderate Essential Hypertension in combination with Hydrochlorothiazide
Combined Modality Therapy
Used to treat patients for whom combination therapy is appropriate in combination with Hydrochlorothiazide
Cardiovascular Mortality
Used to treat Cardiovascular Mortality in combination with Sacubitril
Hypesthesia
Used to treat chronic heart failure with reduced ejection fraction (NYHA Class II-IV) in combination with Sacubitril
Congestive Heart Failure
Used to treat Heart Failure in combination with Sacubitril
Ventricular Dysfunction, Left
Used to treat Systolic Left Ventricular Dysfunction in combination with Sacubitril

Effectiveness

How Diovan Affects PatientsValsartan works by blocking the effects of angiotensin II, a hormone that can raise blood pressure. It is generally taken in an oral dose of 80mg, which will reduce the pressor effect by 80%. Taking valsartan can cause a slight decrease in aldosterone, and may lead to a decrease in total cholesterol, triglycerides, glucose, and uric acid levels. Rarely, it can cause hypotension (low blood pressure), especially in patients who are volume- or salt-depleted or taking high doses of diuretics. In heart failure patients, the incidence of hypotension is 5
How Diovan works in the bodyValsartan is a drug used to treat hypertension, heart failure, and type 2 diabetes-related kidney damage. It is an angiotensin II receptor blocker (ARB) which prevents the hormone angiotensin II from binding to its receptors and causing the body to retain water, narrow blood vessels, and increase blood pressure. This drug also affects the renin-angiotensin aldosterone system, which plays an important role in regulating kidney, vascular, and cardiac functions. Valsartan works by blocking all angiotensin II activity, regardless of where or how it was synthesized. It

When to interrupt dosage

The endorsed dose of Diovan is contingent upon the acknowledged affliction, including initial treatment, Left Ventricular Failure, Unspecified and Combined Modality Therapy. The sum of dosage relies upon the technique of delivery (e.g. Tablet - Oral or Tablet, film coated) delineated in the table below.
Condition
Dosage
Administration
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Diabetic Nephropathies
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Congestive Heart Failure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Type 2 Diabetes
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
High Blood Pressure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Cardiovascular Mortality
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypertensive disease
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Combined Modality Therapy
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
initial treatment
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
multiple antihypertensive drugs likely required
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
not adequately controlled with monotherapy
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Ventricular Dysfunction, Left
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Left Ventricular Failure, Unspecified
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Ventricular Dysfunction, Left
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Heart Failure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral

Warnings

Diovan Contraindications
Condition
Risk Level
Notes
Type 2 Diabetes
Do Not Combine
Breast Milk Production
Do Not Combine
Diabetes
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Valsartan may interact with Pulse Frequency
There are 20 known major drug interactions with Diovan.
Common Diovan Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Valsartan.
Amifostine
Major
Valsartan may increase the hypotensive activities of Amifostine.
Cabozantinib
Major
The metabolism of Cabozantinib can be decreased when combined with Valsartan.
Capecitabine
Major
The metabolism of Capecitabine can be decreased when combined with Valsartan.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Valsartan.
Diovan Toxicity & Overdose RiskTests have shown that the toxic dose of valsartan in rats is greater than 2000mg/kg. When given to pregnant animals, valsartan did not cause any birth defects, but caused lower birth weights and delays in development. If taken during pregnancy, valsartan can harm or kill the fetus and should be stopped right away.
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Diovan Novel Uses: Which Conditions Have a Clinical Trial Featuring Diovan?

510 active trials are being conducted to assess Diovan's potential to ameliorate Type 2 Diabetes, Diabetic Nephropathy and Hypertension.
Condition
Clinical Trials
Trial Phases
Hypesthesia
7 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1
Diabetic Nephropathies
0 Actively Recruiting
Ventricular Dysfunction, Left
1 Actively Recruiting
Phase 2, Phase 3
Type 2 Diabetes
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
High Blood Pressure
4 Actively Recruiting
Not Applicable, Early Phase 1
Congestive Heart Failure
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Hypesthesia
2 Actively Recruiting
Not Applicable
Cardiovascular Mortality
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Ventricular Dysfunction, Left
0 Actively Recruiting
Combined Modality Therapy
0 Actively Recruiting
Heart Failure
0 Actively Recruiting
Left Ventricular Failure, Unspecified
0 Actively Recruiting
Hypesthesia
0 Actively Recruiting
not adequately controlled with monotherapy
0 Actively Recruiting
Hypesthesia
10 Actively Recruiting
Not Applicable, Phase 1
initial treatment
0 Actively Recruiting
multiple antihypertensive drugs likely required
0 Actively Recruiting

Diovan Reviews: What are patients saying about Diovan?

5Patient Review
5/3/2017
Diovan for High Blood Pressure
My blood pressure was really high after taking this pill, even higher than before. I had to go to the emergency room to get it lowered. I would never recommend this drug to anyone.
5Patient Review
6/18/2016
Diovan for Heart Failure
I had great results with this drug, until I was switched to the generic version. The dosage increased from 80, then 60, then 320; doc added lopressor , am now weening off the diovan, every time I take it with the lopressor my BP spikes 160/95 , dizzy blurred vision etc, I think the generic is bogus
4.7Patient Review
11/1/2017
Diovan for High Blood Pressure
Diovan has been my go-to treatment for hypertension for the last three years. It's always kept my blood pressure at a healthy level.
4.3Patient Review
1/7/2017
Diovan for High Blood Pressure
Though my insurance company made me start with this treatment, it was an absolute nightmare. The first day saw my heart racing, and by the second day I had a debilitating headache. My blood pressure dropped to dangerous levels, and I developed shingles within two days. Needless to say, this was not the right medication for me.
4Patient Review
12/20/2017
Diovan for High Blood Pressure
80mg was helpful, but I upped the dosage to 160mg and found that it caused some unpleasant side effects. Reducing the amount to 80mg in the morning and 40mg at night eliminated those problems and gave me better results overall. Also, watch your salt intake!
View All Reviews
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Patient Q&A Section about diovan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between Losartan and Diovan?

"Losartan works for a shorter amount of time than valsartan at lower doses. Research has shown that losartan lasts for less than 24 hours when taken at a dose of 25mg a day or 50mg a day."

Answered by AI

What kind of drug is Diovan?

"Valsartan is used to treat high blood pressure (hypertension) and heart failure.

Valsartan is a drug that belongs to a class of drugs known as angiotensin receptor blockers (ARBs). These drugs work by relaxing blood vessels, which in turn allows blood to flow more easily. Lowering high blood pressure helps to prevent strokes, heart attacks, and kidney problems. Valsartan is used to treat both high blood pressure (hypertension) and heart failure."

Answered by AI

What are the side effects for Diovan?

"The text lists a number of possible symptoms including headaches, dizziness, lightheadedness, tiredness, flu symptoms, upper respiratory infection, diarrhea, and cold symptoms."

Answered by AI

Is Diovan a good blood pressure medicine?

"Diovan (valsartan) is a medication that can help lower blood pressure and protect the kidneys. It is a good first-line option for people with both hypertension and diabetes."

Answered by AI

Clinical Trials for Diovan

Have you considered Diovan clinical trials? We made a collection of clinical trials featuring Diovan, we think they might fit your search criteria.
Have you considered Diovan clinical trials? We made a collection of clinical trials featuring Diovan, we think they might fit your search criteria.
Have you considered Diovan clinical trials? We made a collection of clinical trials featuring Diovan, we think they might fit your search criteria.
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