Limb Occlusion Pressure Tourniquets for Surgery Recovery
(LOP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain. Limb Occlusion Pressure, LOP, is based off the patient's systolic blood pressure plus a safety margin and is typically much lower than standard tourniquet pressure. The aim of this study is to determine if using LOP during orthopedic surgeries decreases post-operative pain and opioid consumption and improves patient's outcomes.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but if you are on prescription pain medications for chronic conditions, you may not be eligible to participate.
Is limb occlusion pressure tourniquet use safe for surgery recovery?
Limb occlusion pressure tourniquets are generally considered safe for use in surgeries, as they help reduce the pressure needed compared to standard tourniquets, potentially lowering the risk of complications like postoperative pain and wound issues. Studies suggest that using limb occlusion pressure can lead to fewer complications and better outcomes in surgeries like knee arthroplasty and carpal tunnel surgery.12345
How does the Limb Occlusion Pressure treatment differ from other treatments for surgery recovery?
What data supports the effectiveness of the treatment Limb Occlusion Pressure Tourniquets for Surgery Recovery?
Research shows that using limb occlusion pressure (LOP) to set tourniquet pressures can reduce postoperative pain and complications compared to standard pressures. Studies in various surgeries, like knee and hand surgeries, found that LOP-based settings lead to less pain and fewer complications.23456
Who Is on the Research Team?
Patrick McCulloch, MD
Principal Investigator
The Methodist Hospital Research Institute
Are You a Good Fit for This Trial?
This trial is for healthy adults over 18 who are having certain orthopedic surgeries like knee replacements or carpal tunnel release. It's not for those on long-term pain meds, with past trauma/surgery in the limb to be operated on, or with blood vessel issues that prevent tourniquet use.Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-operative
Consent obtained and baseline questionnaires completed during a pre-operative office visit
Surgery
Participants undergo orthopedic surgery with either standard or limb occlusion pressure tourniquet
Post-operative Monitoring
Participants keep a daily pain and opioid consumption diary for two weeks after surgery
Follow-up
Participants complete outcome questionnaires to assess recovery and outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Experimental - Limb Occlusion pressure
Find a Clinic Near You
Who Is Running the Clinical Trial?
The Methodist Hospital Research Institute
Lead Sponsor