Tenoretic 100

Slow Heart Rate, Atrial Fibrillation, Migraine + 14 more
Treatment
7 FDA approvals
20 Active Studies for Tenoretic 100

What is Tenoretic 100

AtenololThe Generic name of this drug
Treatment SummaryAtenolol is a type of medication called a beta-blocker. It was developed in the 1980s and is used to treat various cardiovascular conditions. Research has shown that it may not be as effective as other medications in preventing cardiovascular disease and mortality in patients with high blood pressure. Atenolol may be more beneficial for some patients than others, depending on their age and other factors.
Tenorminis the brand name
image of different drug pills on a surface
Tenoretic 100 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tenormin
Atenolol
1990
432

Approved as Treatment by the FDA

Atenolol, otherwise called Tenormin, is approved by the FDA for 7 uses like Refractory Hypertension and Hypertensive disease .
Refractory Hypertension
Used to treat Refractory Hypertension in combination with Chlorthalidone
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Hypertensive disease
Used to treat Refractory Hypertension in combination with Chlorthalidone
Slow Heart Rate
Heart Attack
Hemodynamically Stable
Hypertension

Effectiveness

How Tenoretic 100 Affects PatientsAtenolol is a type of drug used to slow down the heart rate, reduce electrical conductivity, and lower the amount of work that the heart needs to do. This helps reduce the mismatch between oxygen supply and demand and can provide relief from angina pectoris symptoms. It also helps control arrhythmic conditions like atrial fibrillation. Atenolol also helps lower blood pressure, though not as much as other types of beta-blockers, and it does not act on the blood vessels directly. Common side effects of atenolol include fatigue, depression, and sleep disturbances. It can also cause
How Tenoretic 100 works in the bodyAtenolol is a type of drug called a beta-blocker. It binds to beta receptors in the body, particularly those in the heart, and blocks them from responding to normal signals. By blocking these signals, atenolol helps reduce the heart rate and increase the strength of each beat. It also relaxes the smooth muscles of the bronchial tubes, which can help with breathing. Atenolol works by inhibiting certain proteins that control heart rate, contraction strength, and other important processes in the body.

When to interrupt dosage

The suggested amount of Tenoretic 100 is contingent upon the determined condition, such as Atrial Fibrillation, Migraine and Hypertensive disease. The dosage fluctuates as per the technique of administration (e.g. Tablet - Oral or Tablet) featured in the table below.
Condition
Dosage
Administration
Slow Heart Rate
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Atrial Fibrillation
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Syndrome
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Coronary Artery Disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hemodynamically Stable
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Migraine
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertension
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Heart Attack
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Congestive Heart Failure
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Secondary prevention Myocardial infarction
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Thyrotoxicosis
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Migraine Disorders
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Chest Pain
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous

Warnings

Tenoretic 100 has four contraindications and should not be employed with the conditions outlined in the table below.Tenoretic 100 Contraindications
Condition
Risk Level
Notes
Heart Block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Sinus Bradycardia
Do Not Combine
Heart Failure
Do Not Combine
There are 20 known major drug interactions with Tenoretic 100.
Common Tenoretic 100 Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Atenolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Atenolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Atenolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Atenolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Atenolol.
Tenoretic 100 Toxicity & Overdose RiskThe toxic dose of atenolol in mice is 2g/kg when taken orally, 57mg/kg when taken intravenously, 134mg/kg when injected intramuscularly, and 400mg/kg when injected subcutaneously. In rats, the toxic dose is 2g/kg orally and 77mg/kg intravenously. The toxic dose in rabbits is 50mg/kg intravenously. Studies in rats and mice at doses of 300mg/kg per day, which is 150 times the maximum recommended human dose for 18-24 months, did not show any signs of carcinogenicity. However,
image of a doctor in a lab doing drug, clinical research

Tenoretic 100 Novel Uses: Which Conditions Have a Clinical Trial Featuring Tenoretic 100?

626 active clinical trials are currently being conducted to ascertain the potential of Tenoretic 100 in improving Atrial Fibrillation, Coronary Artery Atherosclerosis and Ventricular Tachycardia.
Condition
Clinical Trials
Trial Phases
Secondary prevention Myocardial infarction
0 Actively Recruiting
Congestive Heart Failure
176 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Migraine
55 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Coronary Artery Disease
1 Actively Recruiting
Not Applicable
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Migraine Disorders
1 Actively Recruiting
Phase 3
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Thyrotoxicosis
0 Actively Recruiting
Tachycardia, Ventricular
0 Actively Recruiting
Hypertension
0 Actively Recruiting
Slow Heart Rate
3 Actively Recruiting
Not Applicable
Hemodynamically Stable
0 Actively Recruiting
Hypertensive disease
0 Actively Recruiting
Chest Pain
2 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Tachycardia, Ventricular
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Tenoretic 100 Reviews: What are patients saying about Tenoretic 100?

5Patient Review
4/8/2012
Tenoretic 100 for High Blood Pressure
I found this medication effective at keeping my blood pressure low; however, it made me feel very sleepy and tired. I also had to urinate frequently.
4.7Patient Review
6/9/2011
Tenoretic 100 for High Blood Pressure
Though it caused some pretty severe side effects like dry mouth and anxiety, this medication did lower my blood pressure from 150/100 to 130/90. It also helped remove the excess water weight I was carrying around in my face, legs, and ankles.
4.3Patient Review
5/27/2009
Tenoretic 100 for High Blood Pressure
For two years, this was the only treatment that helped my high blood pressure. However, I developed diabetes and high uric acid levels, which may be due to the chlorthalidone.
4.3Patient Review
2/13/2009
Tenoretic 100 for High Blood Pressure
This treatment effectively solved my high blood pressure problem, which was likely due to genetics.
4.3Patient Review
1/30/2009
Tenoretic 100 for High Blood Pressure
I constantly felt disoriented, tired, and sick while taking this medication.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tenoretic 100

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for tenoretic?

"Atenolol and chlorthalidone are available as 50mg/25mg+ and 100mg/25mg tablets. Both tablet formulations are scored."

Answered by AI

Is tenoretic the same as atenolol?

"This slows down the heart rate and decreases the force of heart muscle contraction. Chlorthalidone is a thiazide "water pill" (diuretic) that helps prevent your body from absorbing too much salt and keeps your potassium levels from getting too low.

Tenoretic is a combination of Atenolol, a selective beta blocker, and Chlorthalidone, a thiazide diuretic. Atenolol works by blocking certain natural compounds that may bind to receptors on the heart, which slows down the heart rate and decreases the force of heart muscle contraction. Chlorthalidone helps prevent your body from absorbing too much salt and keeps your potassium levels from getting too low."

Answered by AI

What drug class is tenoretic?

"Tenoretic is a prescription medicine used to treat the symptoms of High blood pressure (Hypertension). Tenoretic may be used alone or with other medications. Tenoretic is a combination of two drugs, a thiazide diuretic (water pill) and a beta-blocker. Beta-blockers work by slowing down the heart and reducing the amount of blood it pumps out. Thiazide diuretics help reduce the amount of water in the body by increasing the amount of urine produced."

Answered by AI

What is tenoretic used for?

"Atenolol is a beta-blocker that works by relaxing blood vessels and reducing heart rate. Chlorthalidone is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.

This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: atenolol and chlorthalidone. Atenolol is a beta-blocker that works by relaxing blood vessels and reducing heart rate. Chlorthalidone is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water."

Answered by AI

Clinical Trials for Tenoretic 100

Have you considered Tenoretic 100 clinical trials? We made a collection of clinical trials featuring Tenoretic 100, we think they might fit your search criteria.
Have you considered Tenoretic 100 clinical trials? We made a collection of clinical trials featuring Tenoretic 100, we think they might fit your search criteria.
Have you considered Tenoretic 100 clinical trials? We made a collection of clinical trials featuring Tenoretic 100, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top