Depo-Testosterone

Gonadotrophin releasing hormone deficiency, Hypogonadism, Hypogonadism + 7 more
Treatment
12 FDA approvals
5 Active Studies for Depo-Testosterone

What is Depo-Testosterone

Testosterone cypionateThe Generic name of this drug
Treatment SummaryTestosterone cypionate is a drug derived from testosterone used to treat low testosterone in men. It is injected into the body, where it is slowly released and has a long-lasting effect. It was developed by the company Pharmacia and Upjohn and approved by the FDA in 1979.
Depo-Testosteroneis the brand name
image of different drug pills on a surface
Depo-Testosterone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Depo-Testosterone
Testosterone cypionate
1979
51

Approved as Treatment by the FDA

Testosterone cypionate, also known as Depo-Testosterone, is approved by the FDA for 12 uses including Hypergonadotropic Hypogonadism and Pituitary gonadotropin hypofunction .
Hypergonadotropic Hypogonadism
Pituitary gonadotropin hypofunction
Hypothalamic Diseases
Hypogonadism
Orchitis
Orchiectomy
Gonadotrophin releasing hormone deficiency
Hypogonadism
Hypogonadotropic hypogonadism
Testicular hypogonadism
Testicular hypogonadism
Testicular hypogonadism

Effectiveness

How Depo-Testosterone Affects PatientsTestosterone cypionate injections can quickly increase the level of testosterone in the body to four times higher than normal within 24 hours. These high levels of testosterone will last for 3-5 days. This can cause changes in mood and libido, as well as some inflammation where the injection was given.
How Depo-Testosterone works in the bodyTestosterone has two main ways of affecting the body. The first is by directly binding to the androgen receptor, or by being converted into a stronger form known as dihydrotestosterone (DHT). Both of these bind to the same receptor and can enter the cell nucleus, where they influence certain genes and have an androgenic effect on the body.

When to interrupt dosage

The prescribed dosage of Depo-Testosterone is contingent upon the indicated condition, such as Hypergonadotropic Hypogonadism, Testicular hypogonadism and Gonadotrophin releasing hormone deficiency. The amount of dosage depends on the technique of delivery (e.g. Injection, solution or Injection, solution - Intramuscular) noted in the table beneath.
Condition
Dosage
Administration
Gonadotrophin releasing hormone deficiency
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypogonadotropic hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypothalamic Diseases
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Orchitis
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Orchiectomy
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous

Warnings

There are 20 known major drug interactions with Depo-Testosterone.
Common Depo-Testosterone Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Testosterone cypionate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Testosterone cypionate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Testosterone cypionate.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Testosterone cypionate.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone cypionate.
Depo-Testosterone Toxicity & Overdose RiskTests on mice have shown that testosterone implants can cause cervical and uterine tumors that may spread to other parts of the body. Some reports suggest that females taking high doses of testosterone cypionate may be more likely to develop liver cancer, and clinical studies have reported cases of liver cancer in those taking long-term high doses.
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Depo-Testosterone Novel Uses: Which Conditions Have a Clinical Trial Featuring Depo-Testosterone?

Currently, two trials are assessing the potential of Depo-Testosterone to mediate Hypothalamic Diseases, Hypogonadotropic hypogonadism and Orchitis.
Condition
Clinical Trials
Trial Phases
Testicular hypogonadism
5 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Testicular hypogonadism
0 Actively Recruiting
Orchitis
0 Actively Recruiting
Hypogonadotropic hypogonadism
0 Actively Recruiting
Hypogonadism
0 Actively Recruiting
Gonadotrophin releasing hormone deficiency
0 Actively Recruiting
Testicular hypogonadism
0 Actively Recruiting
Hypogonadism
0 Actively Recruiting
Hypothalamic Diseases
0 Actively Recruiting
Orchiectomy
0 Actively Recruiting

Depo-Testosterone Reviews: What are patients saying about Depo-Testosterone?

5Patient Review
12/23/2013
Depo-Testosterone for Rare X Chromosome Abnormality - Klinefelter Syndrome
I've been taking Depo-Testosterone for 20 years and it's really helped me. I was recently diagnosed with prostatic cancer, which has caused my body to stop producing testosterone. As a result, I haven't been able to get erections. My doctor says I can't use the medication anymore.
5Patient Review
1/13/2015
Depo-Testosterone for Breast Cancer that has Spread to Another Part of the Body
This treatment has me feeling great. I have more energy than I have had in a long time, and my breast cancer numbers are staying in the normal range. The only side effect I've experienced is a little bit of weight gain.
5Patient Review
9/21/2012
Depo-Testosterone for Absence of Testicles
This hormone therapy has completely changed my life for the better. I'm transgender, and this treatment allowed me to transition my body into the one I wanted. Not only that, but it also gave me more strength and pulled me out of a massive depression.
5Patient Review
8/7/2010
Depo-Testosterone for Deficient Activity of the Testis
5Patient Review
12/7/2010
Depo-Testosterone for Rare X Chromosome Abnormality - Klinefelter Syndrome
View All Reviews
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Patient Q&A Section about depo-testosterone

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How good is depo-testosterone?

"Almost everyone who has used Depo-Testosterone has had a positive experience with it."

Answered by AI

Does Depo lower testosterone?

"The court has ruled that Depo-Provera, a hormone-suppressing drug which lowers testosterone levels and decreases a man's sex drive, can be used at the discretion of the court for first-time sex offenders."

Answered by AI

What does depo-testosterone do?

"It works by affecting the production of testosterone.

Depo-Testosterone is prescribed to treat impotence, delayed puberty in males, hormonal imbalances, and inoperable breast cancer in women. It may be used alone or with other medications. Depo-Testosterone works by affecting the production of testosterone and belongs to a class of drugs called Androgens."

Answered by AI

What are the side effects of Depo-testosterone?

"If you experience any of the following side effects, you should tell your doctor or pharmacist: Nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, acne, pain, and redness at the injection site."

Answered by AI

Clinical Trials for Depo-Testosterone

Have you considered Depo-Testosterone clinical trials? We made a collection of clinical trials featuring Depo-Testosterone, we think they might fit your search criteria.
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