Your session is about to expire
What is Depo-Testosterone
Testosterone cypionateThe Generic name of this drug
Treatment SummaryTestosterone cypionate is a drug derived from testosterone used to treat low testosterone in men. It is injected into the body, where it is slowly released and has a long-lasting effect. It was developed by the company Pharmacia and Upjohn and approved by the FDA in 1979.
Depo-Testosteroneis the brand name
Depo-Testosterone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Depo-Testosterone
Testosterone cypionate
1979
51
Approved as Treatment by the FDA
Testosterone cypionate, also known as Depo-Testosterone, is approved by the FDA for 10 uses including Pituitary gonadotropin hypofunction and Hypothalamic Diseases .Pituitary gonadotropin hypofunction
Hypothalamic Diseases
Orchiectomy
Hypogonadotropic hypogonadism
Orchitis
Testicular hypogonadism
Testicular hypogonadism
Gonadotrophin releasing hormone deficiency
Hypergonadotropic Hypogonadism
Testicular hypogonadism
Effectiveness
How Depo-Testosterone Affects PatientsTestosterone cypionate injections can quickly increase the level of testosterone in the body to four times higher than normal within 24 hours. These high levels of testosterone will last for 3-5 days. This can cause changes in mood and libido, as well as some inflammation where the injection was given.
How Depo-Testosterone works in the bodyTestosterone has two main ways of affecting the body. The first is by directly binding to the androgen receptor, or by being converted into a stronger form known as dihydrotestosterone (DHT). Both of these bind to the same receptor and can enter the cell nucleus, where they influence certain genes and have an androgenic effect on the body.
When to interrupt dosage
The prescribed dosage of Depo-Testosterone is contingent upon the indicated condition, such as Hypergonadotropic Hypogonadism, Testicular hypogonadism and Gonadotrophin releasing hormone deficiency. The amount of dosage depends on the technique of delivery (e.g. Injection, solution or Injection, solution - Intramuscular) noted in the table beneath.Condition
Dosage
Administration
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Orchitis
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Testicular hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypergonadotropic Hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypothalamic Diseases
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Hypogonadotropic hypogonadism
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Gonadotrophin releasing hormone deficiency
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Pituitary gonadotropin hypofunction
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Orchiectomy
200.0 mg/mL, , 100.0 mg/mL, 20.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Injection, Injection - Intramuscular, Solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Intramuscular; Topical, Injection - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous
Warnings
There are 20 known major drug interactions with Depo-Testosterone.Common Depo-Testosterone Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Testosterone cypionate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Testosterone cypionate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Testosterone cypionate.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Testosterone cypionate.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone cypionate.
Depo-Testosterone Toxicity & Overdose RiskTests on mice have shown that testosterone implants can cause cervical and uterine tumors that may spread to other parts of the body. Some reports suggest that females taking high doses of testosterone cypionate may be more likely to develop liver cancer, and clinical studies have reported cases of liver cancer in those taking long-term high doses.
Depo-Testosterone Novel Uses: Which Conditions Have a Clinical Trial Featuring Depo-Testosterone?
Currently, two trials are assessing the potential of Depo-Testosterone to mediate Hypothalamic Diseases, Hypogonadotropic hypogonadism and Orchitis.Condition
Clinical Trials
Trial Phases
Gonadotrophin releasing hormone deficiency
1 Actively Recruiting
Phase 1
Orchiectomy
0 Actively Recruiting
Hypogonadotropic hypogonadism
0 Actively Recruiting
Hypothalamic Diseases
0 Actively Recruiting
Hypergonadotropic Hypogonadism
0 Actively Recruiting
Testicular hypogonadism
0 Actively Recruiting
Pituitary gonadotropin hypofunction
0 Actively Recruiting
Testicular hypogonadism
0 Actively Recruiting
Testicular hypogonadism
0 Actively Recruiting
Orchitis
0 Actively Recruiting
Depo-Testosterone Reviews: What are patients saying about Depo-Testosterone?
5Patient Review
12/23/2013 I've been taking Depo-Testosterone for 20 years and it's really helped me. I was recently diagnosed with prostatic cancer, which has caused my body to stop producing testosterone. As a result, I haven't been able to get erections. My doctor says I can't use the medication anymore.
5Patient Review
1/13/2015 This treatment has me feeling great. I have more energy than I have had in a long time, and my breast cancer numbers are staying in the normal range. The only side effect I've experienced is a little bit of weight gain.
5Patient Review
9/21/2012 This hormone therapy has completely changed my life for the better. I'm transgender, and this treatment allowed me to transition my body into the one I wanted. Not only that, but it also gave me more strength and pulled me out of a massive depression.
5Patient Review
8/7/20105Patient Review
12/7/20105Patient Review
12/30/20102.7Patient Review
9/16/2012 The Depo-Testosterone treatment alleviated my symptoms, but they returned when I was given a generic equivalent by the pharmacy. Make sure to get the real thing if it's working for you!
Patient Q&A Section about depo-testosterone
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How good is depo-testosterone?
"Almost everyone who has used Depo-Testosterone has had a positive experience with it."
Answered by AI
Does Depo lower testosterone?
"The court has ruled that Depo-Provera, a hormone-suppressing drug which lowers testosterone levels and decreases a man's sex drive, can be used at the discretion of the court for first-time sex offenders."
Answered by AI
What does depo-testosterone do?
"It works by affecting the production of testosterone.
Depo-Testosterone is prescribed to treat impotence, delayed puberty in males, hormonal imbalances, and inoperable breast cancer in women. It may be used alone or with other medications. Depo-Testosterone works by affecting the production of testosterone and belongs to a class of drugs called Androgens."
Answered by AI
What are the side effects of Depo-testosterone?
"If you experience any of the following side effects, you should tell your doctor or pharmacist: Nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, acne, pain, and redness at the injection site."
Answered by AI