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What is Metrogel-Vaginal
MetronidazoleThe Generic name of this drug
Treatment SummaryMetronidazole is a prescription antibiotic used to treat various infections. It belongs to the nitroimidazole family of antibiotics and is effective in treating bacterial and parasitic infections, such as trichomoniasis, giardiasis, amebiasis, and gastrointestinal infections. Metronidazole is available as a pill, capsule, topical cream, and suppository. It has been used for decades to treat infections and continues to be an effective treatment option.
Flagylis the brand name
Metrogel-Vaginal Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Flagyl
Metronidazole
1963
449
Approved as Treatment by the FDA
Metronidazole, commonly known as Flagyl, is approved by the FDA for 25 uses including Bacterial Septicemia and Bacterial Infections .Bacterial Septicemia
Bacterial Infections
Abscess, Intra-Abdominal
Lung Abscess
Endomyometritis
Empyema
Central Nervous System Bacterial Infections
Bacterial Peritonitis
Pneumonia
Abdominal Infection
Liver Abscess
Endometritis
Tubo-ovarian abscess
Bacterial Endocarditis
Bacteria, Anaerobic
Communicable Diseases
Bacteria
Communicable Diseases
Curling Ulcer
Used to treat Duodenal Ulcer in combination with Bismuth subsalicylate
Bone and Joint Infections
Abscess
Helicobacter Pylori Infection
Used to treat Helicobacter Pylori Infection in combination with Bismuth subsalicylate
Bacterial Meningitis
Trichomonas Infections
Exposure via partner
Effectiveness
How Metrogel-Vaginal Affects PatientsMetronidazole is used to treat certain bacterial and parasitic infections, including amebiasis, trichomoniasis, and giardiasis. It is effective against most anaerobic bacteria, but not against facultative anaerobes or obligate aerobes. This is because it damages the DNA of the microbes it targets. It is important to be aware that taking metronidazole can cause convulsions and peripheral neuropathy, especially at higher doses. If these symptoms occur, the drug should be stopped immediately. Additionally, it has been found to be carcinogenic in mice and rats. The effects on humans
How Metrogel-Vaginal works in the bodyMetronidazole works by entering cells and breaking down into toxic metabolites. These metabolites can damage the DNA of certain organisms, like anaerobic bacteria and protozoans. Metronidazole is only toxic to these organisms because of the difference in their electron transport systems. When the nitro group of metronidazole is reduced by ferredoxin or flavodoxin, it creates toxic metabolites that can damage the DNA of the target organisms.
When to interrupt dosage
The dose of Metrogel-Vaginal is contingent upon the determined condition, including Exposure via partner, Skin and Curling Ulcer. The measure likewise differs depending on the method of delivery (e.g. Capsule or Vaginal) featured in the table beneath.Condition
Dosage
Administration
Vaginal Candidiasis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Uterine Cervical Erosion
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Empyema
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
symptomatic Trichomoniasis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Bacterial Meningitis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Bacterial Peritonitis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Exposure via partner
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Amebic colitis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Atopic Dermatitis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Skin
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Helicobacter Pylori Infection
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Communicable Diseases
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Abdominal Infection
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Bone and Joint Infections
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Bacteria, Anaerobic
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Bacterial Infections
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Pneumonia
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Sinusitis
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Liver Abscess
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Liver Abscess, Amebic
5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Topical, Gel - Topical, Gel, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Vaginal, Gel - Vaginal, Solution, Solution - Intravenous, Lotion, Lotion - Topical, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Kit, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated - Oral, Tablet, coated, Injection - Intravenous, Kit - Oral, Ointment - Topical, Ointment, Insert, Insert - Vaginal
Warnings
Metrogel-Vaginal has three contraindications and should not be utilized if you are experiencing any of the conditions in the following table.Metrogel-Vaginal ContraindicationsCondition
Risk Level
Notes
Pregnancy Trimester, First
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Metronidazole may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Metronidazole may interact with Pulse Frequency
Common Metrogel-Vaginal Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Metronidazole.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Metronidazole.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Metronidazole.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Metronidazole.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Metronidazole.
Metrogel-Vaginal Toxicity & Overdose RiskThe toxic dose of metronidazole in rats is 5000mg/kg. Overdosing on metronidazole can cause symptoms like nerve damage, brain toxicity, seizures, an unpleasant reaction if combined with alcohol, dark urine, a bad taste in the mouth, nausea, stomach pain, and dizziness, as well as a decrease in white blood cells. If someone overdoses on this drug, activated charcoal can help remove it from the body and poison control centers should be contacted for additional guidance.
Metrogel-Vaginal Novel Uses: Which Conditions Have a Clinical Trial Featuring Metrogel-Vaginal?
179 active studies are examining the potential of Metrogel-Vaginal to mitigate Curling Ulcer, Periodontitis and Central Nervous System Bacterial Infections.Condition
Clinical Trials
Trial Phases
Giardiasis
0 Actively Recruiting
Abdominal Infection
0 Actively Recruiting
Bacterial Endocarditis
0 Actively Recruiting
prophylaxis of Postoperative Infections
0 Actively Recruiting
Pneumonia
62 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Early Phase 1, Phase 4
Rosacea
0 Actively Recruiting
post-surgical vaginal cuff infection
0 Actively Recruiting
Vaginitis
0 Actively Recruiting
Lung Abscess
0 Actively Recruiting
Tubo-ovarian abscess
0 Actively Recruiting
Sinusitis
0 Actively Recruiting
Trichomonas Infections
0 Actively Recruiting
Postoperative Infections
0 Actively Recruiting
Inflammatory pustules
0 Actively Recruiting
Elective Colorectal Surgery
0 Actively Recruiting
Candida albicans
0 Actively Recruiting
Liver Abscess
0 Actively Recruiting
Vaginal Candidiasis
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Bone and Joint Infections
0 Actively Recruiting
Metrogel-Vaginal Reviews: What are patients saying about Metrogel-Vaginal?
5Patient Review
10/5/2015 I have BV because of the foul smell when I urinate. As much as I try avoiding to go to gyn, the only thing that takes care of this problem for me is this medicine. It works by the second day, but I take the full five day course 1x/day so it stays at bay for a while. The cottage cheese discharge while using the medicine is normal and I also experience light cramping after tbe third day til I am done with the medicine
5Patient Review
7/29/2019 I just completed a five-day treatment of this medication and I'm already feeling so much better. I experienced some cramping on day three, as well as the discharge that indicates the medication is working, but those were really the only side effects I noticed.
4.3Patient Review
10/31/2018 I experienced a lot of pain and cramping while using this treatment. I also had stomach issues and a lot of discharge. The burning sensations and pressure were also very unpleasant. Overall, I hope it worked but it was definitely not a pleasant experience.
4.3Patient Review
10/25/2022 Some people will complain about anything, but the gel is actually working if you're experiencing clumping of your vaginal discharge. I've had wine while using it with no negative consequences, and it takes away BV after just five days. If you want to be productive, get your male partners treated for BV while you're getting treated yourself.
4Patient Review
2/4/2016 I was pleasantly surprised that there wasn't any discomfort when inserting the medication. It didn't leak out, even when I was standing up (although I used it before bed and tried to stay lying down). Currently on day 4, symptoms for BV are gone, now just worried about a possible yeast infection after reading the reviews! Eating lots of yogurt in the meantime. Very happy with this product!
3.7Patient Review
6/27/2021 I was prescribed this gel by my gyno to treat recurring bv. I used it once per week for six months as directed, but found that each time I did so, I would end up with a week of really heavy discharge afterwards. It was incredibly inconvenient and messy, so I stopped using it after the six months were up.
2.7Patient Review
3/12/2016 I have now been using this gel for five days. I experience cramps every night, but they aren't too bad (a four out of ten on the pain scale). The white, wet discharge is really unpleasant though. I hope I don't get a yeast infection after I finish the treatment.
2.7Patient Review
8/3/2016 I got bacterial vaginosis for the first time post-menopause. My doctor prescribed this gel to use for five nights before bed. It's easy to insert and didn't cause too much leaking when I wake in night time to go to bathroom, but one month later I got BV again. The second time my doctor prescribed this for me again, but it caused inflammation of my internal vaginal tissues, so she told me to stop it after day three. Will not use again.
1Patient Review
10/6/2019 The cramps, anxiety, and depression I felt after taking this medication were absolutely unbearable. I ended up having to take a different medication (clindimyicin) and it worked much better.
1Patient Review
6/21/2020 I unfortunately had an allergic reaction in the form of urticaria.
Patient Q&A Section about metrogel-vaginal
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Metrogel VAG gel used for?
"This drugs is used to treat bacterial infections in the vagina. It works by stopping the growth of the bacteria."
Answered by AI
How long does it take for Metrogel to work for BV?
"Cigna Health states that most BV treatments will get rid of symptoms within two to three days, but it is recommended that you finish the treatment for BV within seven days."
Answered by AI
What are the side effects of Metrogel?
"If you experience any negative effects after taking this medication, such as a burning feeling, skin irritation, dryness, redness, metallic taste, nausea, or headache, tell your doctor or pharmacist right away."
Answered by AI
How do I use Metrogel for BV?
"If you are an adult, insert one 500 milligram tablet high into your vagina once a day in the evening for 10 or 20 days. If you are a child, your doctor will determine how much of the medicine you should use and how often you should use it."
Answered by AI