Vulvovaginal Candidiasis
1 FDA approval
1 Active Study for Terconazole

What is Terconazole

TerconazoleThe Generic name of this drug
Treatment SummaryTerconazole is an anti-fungal drug used to treat vaginal yeast infections. It was approved by the FDA in 1987 and is available in cream and suppository forms. Studies have shown that it is a safe and effective treatment for this condition.
Terazol 7is the brand name
Terconazole Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Terazol 7

Approved as Treatment by the FDA

Terconazole, otherwise called Terazol 7, is approved by the FDA for 1 uses which include Vulvovaginal Candidiasis .
Vulvovaginal Candidiasis


How Terconazole Affects PatientsTerconazole is a medication used to treat fungal infections that is inserted into the vagina. It works by disrupting the structure and functions of the fungal membrane, which stops the fungus from growing. This is done by blocking an enzyme (lanosterol 14-alpha-demethylase) that helps make a substance (ergosterol) needed for the fungal membrane.
How Terconazole works in the bodyTerconazole works by disrupting the cell membranes of fungi. It stops an enzyme called cytochrome P450 14-alpha-demethylase, which leads to a build-up of certain sterols in the membrane. This disrupts the structure and function of the fungal cell and prevents it from growing.

When to interrupt dosage

The proposed dose of Terconazole is reliant upon the diagnosed disorder. The measure of dosage differs as per the technique of delivery listed in the following table.
Vulvovaginal Candidiasis
80.0 mg, 0.008 mg/mg, , 0.4 %, 0.004 mg/mg, 0.8 %
, Cream; Insert; Kit - Vaginal, Insert, Cream, Suppository - Vaginal, Cream - Vaginal, Vaginal, Suppository, Cream; Insert; Kit, Insert - Vaginal


Common Terconazole Drug Interactions
Drug Name
Risk Level
Terconazole Toxicity & Overdose RiskThe highest toxic dose of the drug that is lethal to half of the population has been determined to be 1741mg/kg for male rats and 849mg/kg for female rats.

Terconazole Novel Uses: Which Conditions Have a Clinical Trial Featuring Terconazole?

An ongoing clinical trial is assessing the utility of Terconazole in providing relief from Vulvovaginal Candidiasis.
Clinical Trials
Trial Phases
Vulvovaginal Candidiasis
1 Actively Recruiting
Phase 3

Terconazole Reviews: What are patients saying about Terconazole?

5Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I was hesitant to use this treatment because of the reviews I had read, but I'm glad I did. It didn't burn or itch at all.
5Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I was hesitant to use this product after reading all the negative reviews, but I'm glad I did. It provided relief from my yeast infection symptoms almost immediately. I would definitely recommend it to other pregnant women.
4.7Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
Diflucan didn't work for my yeast infection so I tried this cream per my doctor's recommendation. It didn't burn or itch like Monistat did, which was a relief. I'm not sure if it actually worked because there wasn't a noticeable change in discharge, but my symptoms gradually stopped.
4.3Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
This didn't have any of the negative side effects that Monistat did, but it was still pretty messy.
3Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I'm on day six of this treatment and I've had severe bloating, fullness, and cramps the whole time. Not to mention the headaches!
2.3Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
Even after completing the full course, I still feel like I have the infection.
2.3Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
The tube that comes with this product needs improvement. It's difficult to use and the cream gets everywhere.
2Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I had a really negative reaction to this medication and ended up in the emergency room. The flu-like symptoms were accompanied by a high fever, and the next day my muscles ached all over my body. If you're sensitive to any similar medications, I would recommend avoiding this one.
1.7Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I would not recommend this to anyone. I had a yeast infection for over a week and after taking two doses of diflucin, it didn't work. So, my doctor prescribed this medication. I used it one night and woke up feeling worse than before I started the medication. It was very uncomfortable with all the itching and swelling. There has to be something better out there for females who suffer from these types of infections.
1.7Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
This product is very difficult to use. The metal tube is hard to squeeze, and the cream goes everywhere except in the applicator. I was only able to use it once before giving up. Terrible design, waste of money..
1Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I used this for a yeast infection that I'd had for a few months. I took the prescribed doses, and then woke up feeling awful the next morning: feverish and with severe body aches. My doctor said it was either a side effect of the medicine or a viral infection, so I stopped taking it. The next morning I felt fine again.
1Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
The application process for this treatment was really painful and difficult because of my yeast infection. The itching got worse while I was using it, and I started to feel weak and sick. My baby also became less active.
1Patient Review
Terconazole for Yeast Infection of Vagina and Vulva
I had an awful headache, my vagina was burning, and I was shaking within two hours of using this product.

Patient Q&A Section about terconazole

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for terconazole to work?

"The drug terconazole begins to take effect 5 to 10 hours after being inserted into the vagina, and you may see an improvement in symptoms within 1 or 2 days. It is important to finish the whole course of treatment to make sure the infection is completely cleared."

Answered by AI

What are the side effects of terconazole?

"You may experience a headache, body pain, vaginal pain, burning, or itching, stomach pain, or increased menstrual cramps."

Answered by AI

What is terconazole cream used for?

"Terconazole is an anti-fungal medication used to treat vaginal fungal or yeast infections. It works by killing the fungus or yeast and preventing its growth. It is available only with a doctor's prescription."

Answered by AI

Clinical Trials for Terconazole