Aminophyllin

Bronchospasm, Asthma, Bronchial Asthma + 4 more
Treatment
20 Active Studies for Aminophyllin

What is Aminophyllin

AminophyllineThe Generic name of this drug
Treatment SummaryAminophylline is a combination of two drugs, theophylline and ethylenediamine, used to treat lung diseases such as asthma, chronic bronchitis, and COPD. It works by blocking certain receptors and activating an enzyme in the body. Although it was once widely used, most aminophylline medications have been discontinued and the remaining medications are in limited supply.
Aminophyllineis the brand name
image of different drug pills on a surface
Aminophyllin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Aminophylline
Aminophylline
1975
22

Effectiveness

How Aminophyllin Affects PatientsAminophylline is a drug made from the compound theophylline. It has several effects on the body, such as increasing alertness, stimulating muscles, and relaxing the muscles in the airways. It also causes an increase in urine production and more acid to be produced in the stomach.
How Aminophyllin works in the bodyAminophylline is a medicine that helps to open up the airways in your lungs, making it easier to breathe. It does this by blocking certain enzymes and receptors that cause tightness and constriction in the airways. It also helps to reduce inflammation, which can make breathing even more difficult.

When to interrupt dosage

The prescribed dosage of Aminophyllin is contingent upon the indicated disorder, including Chronic Bronchitis, Lung Disorder and Bronchospasm. The measure of dosage fluctuates as per the approach of delivery (e.g. Intravenous or Suppository) featured in the table beneath.
Condition
Dosage
Administration
Chronic Bronchitis
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Bronchial Asthma
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Bronchitis
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Bronchospasm
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Asthma
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Lung Disorder
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal
Asthma
, 97.5 mg, 225.0 mg, 350.0 mg, 100.0 mg, 200.0 mg, 25.0 mg/mL, 105.0 mg/mL, 500.0 mg, 250.0 mg, 50.0 mg/mL
, Intravenous, Solution - Intravenous, Solution, Oral, Tablet, Tablet - Oral, Tablet, extended release - Oral, Tablet, extended release, Injection, solution, Injection, solution - Intravenous, Solution - Oral, Injection, Injection - Intravenous, Rectal, Suppository, Suppository - Rectal

Warnings

There are 20 known major drug interactions with Aminophyllin.
Common Aminophyllin Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Aminophylline.
Amobarbital
Major
The therapeutic efficacy of Amobarbital can be decreased when used in combination with Aminophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Aminophylline.
Barbexaclone
Major
The therapeutic efficacy of Barbexaclone can be decreased when used in combination with Aminophylline.
Barbital
Major
The therapeutic efficacy of Barbital can be decreased when used in combination with Aminophylline.
image of a doctor in a lab doing drug, clinical research

Aminophyllin Novel Uses: Which Conditions Have a Clinical Trial Featuring Aminophyllin?

158 active clinical trials are currently being conducted to assess the potential of Aminophyllin to provide relief from Bronchitis, Chronic Bronchitis and Asthma.
Condition
Clinical Trials
Trial Phases
Bronchitis
0 Actively Recruiting
Bronchospasm
0 Actively Recruiting
Asthma
162 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3
Asthma
1 Actively Recruiting
Not Applicable
Bronchial Asthma
1 Actively Recruiting
Phase 3
Chronic Bronchitis
4 Actively Recruiting
Not Applicable, Phase 3
Lung Disorder
7 Actively Recruiting
Not Applicable, Phase 1, Phase 2

Patient Q&A Section about aminophyllin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is difference between aminophylline and theophylline?

"Theophylline stimulates the central nervous system, skeletal muscles, and cardiac muscle. It relaxes certain smooth muscles in the bronchi, produces diuresis, and causes an increase in gastric secretion."

Answered by AI

What is another name for aminophylline?

"There are several brands of theophylline available, including Theo 24, Theochron, Elixophyllin, aminophylline, and Uniphyl."

Answered by AI

What is aminophylline used for?

"Aminophylline is used in conjunction with other medications to manage the acute symptoms of asthma, bronchitis, emphysema, and other pulmonary disorders in a hospital setting. Aminophylline is classified as a bronchodilator."

Answered by AI

Why Aminophylline is given slowly?

"Aminophylline should be administered intravenously slowly to avoid dangerous side-effects that stimulate the central nervous system and cardiovascular system. The rate should not exceed 25 mg/min."

Answered by AI

Clinical Trials for Aminophyllin

Have you considered Aminophyllin clinical trials? We made a collection of clinical trials featuring Aminophyllin, we think they might fit your search criteria.
Have you considered Aminophyllin clinical trials? We made a collection of clinical trials featuring Aminophyllin, we think they might fit your search criteria.
Have you considered Aminophyllin clinical trials? We made a collection of clinical trials featuring Aminophyllin, we think they might fit your search criteria.