Your session is about to expire
What is Monurol
FosfomycinThe Generic name of this drug
Treatment SummaryFosfomycin is an antibiotic discovered in 1969 by Spanish scientists. It is available in both oral and intravenous forms, and is usually taken as a single 3-gram dose. Fosfomycin is most commonly used to treat uncomplicated urinary tract infections in women, but it has a broad spectrum of activity and can be used to treat other bacterial infections. This drug is generally well tolerated with a good safety profile.
Monurolis the brand name
Monurol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Monurol
Fosfomycin
1996
8
Approved as Treatment by the FDA
Fosfomycin, also known as Monurol, is approved by the FDA for 2 uses such as Enterococcus faecalis and Escherichia coli .Enterococcus faecalis
Escherichia coli
Effectiveness
How Monurol Affects PatientsFosfomycin is primarily used to treat urinary tract infections, but has also been found to work with other antibiotics to fight bacteria. It has been effective against certain tough-to-treat bacteria like MRSA and multi-drug resistant enterobacteria. This is because fosfomycin works differently than other antibiotics, meaning there is a lower chance of it becoming resistant. Fosfomycin can also help the body's immune system by modifying the response to inflammation and helping white blood cells destroy germs. Additionally, fosfomycin is able to penetrate and break down biofilms, and can kill bacteria
How Monurol works in the bodyFosfomycin works by disabling a key enzyme that helps create bacterial cell walls. By blocking the enzyme, it prevents bacteria from forming the structure that holds them together. Fosfomycin is also able to enter bacterial cells in two different ways, allowing it to do its job more effectively. Finally, it can stop bacteria from attaching to cells in areas like the urinary or respiratory tract.
When to interrupt dosage
The amount of Monurol is contingent upon the determined affliction, including Urinary tract infection, Enterococcus faecalis and Escherichia coli. Dosage varies, based on the method of administration (e.g. Powder, for solution - Intravenous or Oral) featured in the table beneath.Condition
Dosage
Administration
Urinary tract infection
, 3000.0 mg, 2000.0 mg, 8000.0 mg, 4000.0 mg
, Oral, Powder, Powder - Oral, Powder, for solution, Intravenous, Powder, for solution - Intravenous, Powder, for solution - Oral, Granule, for solution, Granule, for solution - Oral
Enterococcus faecalis
, 3000.0 mg, 2000.0 mg, 8000.0 mg, 4000.0 mg
, Oral, Powder, Powder - Oral, Powder, for solution, Intravenous, Powder, for solution - Intravenous, Powder, for solution - Oral, Granule, for solution, Granule, for solution - Oral
Escherichia coli
, 3000.0 mg, 2000.0 mg, 8000.0 mg, 4000.0 mg
, Oral, Powder, Powder - Oral, Powder, for solution, Intravenous, Powder, for solution - Intravenous, Powder, for solution - Oral, Granule, for solution, Granule, for solution - Oral
Warnings
Monurol ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Fosfomycin may interact with Pulse Frequency
Common Monurol Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Fosfomycin.
Abacavir
Minor
Fosfomycin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Aclidinium
Minor
Fosfomycin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Fosfomycin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Fosfomycin may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Monurol Toxicity & Overdose RiskAnimals have been found to tolerate doses of fosfomycin up to 50-125 times higher than what is typically prescribed to humans without any severe side effects, though some rabbits and dogs experienced minor to moderate diarrhea. For humans, an overdose may lead to hearing loss, balance issues, reduced taste perception, and a metallic taste. If someone overdoses on fosfomycin, they should be given treatment to alleviate their symptoms and provide supportive care.
Monurol Novel Uses: Which Conditions Have a Clinical Trial Featuring Monurol?
Two investigations are currently being conducted to analyze the effect of Monurol in treating Enterococcus faecalis, Urinary tract infection and Escherichia coli.Condition
Clinical Trials
Trial Phases
Escherichia coli
0 Actively Recruiting
Enterococcus faecalis
0 Actively Recruiting
Urinary tract infection
2 Actively Recruiting
Phase 2, Phase 3
Monurol Reviews: What are patients saying about Monurol?
5Patient Review
8/6/2018 Unfortunately, this led to some sudden and intense diarrhea. However, it did clear up the infection within three days.
5Patient Review
2/6/2022 This medication worked very well for me, despite some initial digestive issues. I'm really happy to have found a solution that works.
5Patient Review
11/26/2021 I really wish my doctor had prescribed this to me sooner. I get UTIs semi-regularly and the pills are always so unpleasant, not to mention easy to forget. This product is excellent.
5Patient Review
9/6/2019 I was very hesitant to try this, as it just seemed like a packet of flavored powder. I'm also allergic to many antibiotics, but I decided to give it a chance. Within 3 hours of taking it, all my symptoms had disappeared. No more bloating, burning, or needing to go constantly. This drug is amazing! The only downside is the stomach cramps that come along with it; however, they were manageable.
4Patient Review
2/3/2019 I've tried Monurol a few times now to treat my UTIs, but I haven't had any luck with it. Each time, the infection comes back within a few months.
4Patient Review
5/16/2020 The infection eventually cleared up, but the drug caused some really unpleasant diarrhea that lasted for three days. Additionally, the symptoms of the UTI didn't completely go away until four days after beginning treatment.
4Patient Review
4/9/2018 This didn't work for me unfortunately. It made my symptoms worse and I suffered for five days total. However, I did find that natural products like VitaCist, Sisu vitamine C, and probiotics were effective. One dose of VitaCist was enough to see benefits right away. Monurol was the worst for me out of everything I tried.
4Patient Review
6/26/2018 Easy to use, but contains saccharin. I would not have taken it if I had known that beforehand. However, it is still better than the alternatives which rarely work. I think it has worked so far, but it has only been six days.
4Patient Review
4/24/2018 I took the medication as directed, but unfortunately saw little to no results. I'm still feeling the same stinging sensation. Very disappointing.
2.3Patient Review
12/21/2019 I was recommended this by a professional for my chronic UTIs. Unfortunately, it didn't work for me.
2.3Patient Review
1/22/2022 I've had a lot of UTIs and this is the only medication that I want to use. Most traditional meds given by doctors cause severe side effects but this one beats everything else. The symptoms are relieved quickly!
2.3Patient Review
11/7/2018 This treatment has been really helpful in keeping me out of the hospital. The only problem is that it's hard for me to get when I need it because of the price.
2.3Patient Review
12/21/2019 I was really hoping this drug would work for me, but unfortunately it did not. The symptoms actually got worse the day after taking it. If your doctor prescribes this medication, definitely ask for something else instead.
2Patient Review
4/17/2018 While this treatment did successfully address my UTI symptoms, I experienced incredibly unpleasant and severe diarrhea as a result.
1.3Patient Review
4/18/2018 I was really hoping this would work based on the reviews, but it didn't do anything for me. I'm still in a lot of pain and will have to try something else.
1Patient Review
3/3/2018Patient Q&A Section about monurol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is monurol a good antibiotic?
"Most people who voted found this review helpful. Monurol is a great medication for treating UTIs. It always works for me, getting rid of the infection and the accompanying pain, burning, and urgency."
Answered by AI
How long does it take monurol to work?
"You should notice an improvement in your symptoms within 2 to 3 days of taking fosfomycin (Monurol). However, if your symptoms do not improve, contact your healthcare provider."
Answered by AI
How long does it take for monurol to work for UTI?
"Although MONUROL only needs to be taken once, it is designed to remain in your bladder for more than three days in order to continuously kill the bacteria. MONUROL should start working to kill bacteria a few hours after taking it. As a result, you should experience an improvement in your symptoms after two or three days."
Answered by AI
What is monurol used to treat?
"This is an antibiotic that is used to treat bladder infections in women. It works by stopping the growth of bacteria. This antibiotic can only treat bacterial infections and not viral infections."
Answered by AI