Aromasin

Advance Directives, Postmenopause, Breast + 1 more

Treatment

5 FDA approvals

17 Active Studies for Aromasin

Treatment for

Advance Directives

What is Aromasin

ExemestaneThe Generic name of this drug

Treatment SummaryExemestane is a pill that helps treat hormone-receptor-positive breast cancer in postmenopausal women. It works by blocking the aromatase enzyme from converting other hormones into estrogen. This prevents the cancer cells from using estrogen and stops the growth of the tumor.

Aromasinis the brand name

image of different drug pills on a surface

Aromasin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aromasin

Exemestane

1999

Approved as Treatment by the FDA

Exemestane, also known as Aromasin, is approved by the FDA for 5 uses which include Early Breast Cancer and 2-3 years of tamoxifen therapy .

Early Breast Cancer

2-3 years of tamoxifen therapy

Postmenopause

Breast

Advance Directives

Effectiveness

How Aromasin Affects PatientsAromatase inhibitors (AIs) are drugs that limit the amount of the hormone estrogen in the body by blocking the action of the enzyme aromatase. Selective AIs (SAIs) target just estrogen and leave other hormones produced by the adrenal glands alone. Examples of SAIs include anastrozole, letrozole, and exemestane.

How Aromasin works in the bodyExemestane is used to treat postmenopausal breast cancer. It works by blocking an enzyme called aromatase, which converts androgens to estrogens. Estrogen encourages the growth of some breast cancer cells, so blocking it can reduce the growth of cancer cells. Exemestane binds to the active site of the aromatase enzyme, which prevents it from working and reduces estrogen levels. Exemestane does not affect other enzymes in the body, and does not interfere with the production of corticosteroids or aldosterone. Reducing the amount of estrogen in the body can slow down tumor growth and help stop

When to interrupt dosage

The measure of Aromasin depends on the diagnosed condition, such as 2-3 years of tamoxifen therapy, Advance Directives and Breast. The amount of dosage is contingent upon the technique of delivery (e.g. Tablet - Oral or Tablet, film coated) noted in the table underneath.

Condition

Dosage

Administration

Advance Directives

, 25.0 mg

, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral

Postmenopause

, 25.0 mg

, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral

Breast

, 25.0 mg

, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral

2-3 years of tamoxifen therapy

, 25.0 mg

, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral

Warnings

There are 3 known major drug interactions with Aromasin.

Common Aromasin Drug Interactions

Drug Name

Risk Level

Description

Haloperidol

Moderate

The serum concentration of Haloperidol can be increased when it is combined with Exemestane.

Methadone

Moderate

The serum concentration of Methadone can be increased when it is combined with Exemestane.

Tucatinib

Moderate

The metabolism of Tucatinib can be decreased when combined with Exemestane.

Aromasin Toxicity & Overdose RiskSeizures

image of a doctor in a lab doing drug, clinical research

Aromasin Novel Uses: Which Conditions Have a Clinical Trial Featuring Aromasin?

Currently, there are 20 active studies investigating the potential of Aromasin to provide Advance Directives, 2-3 years of tamoxifen therapy and Postmenopausal relief.

Condition

Clinical Trials

Trial Phases

Advance Directives

0 Actively Recruiting

2-3 years of tamoxifen therapy

0 Actively Recruiting

Breast

9 Actively Recruiting

Phase 2, Not Applicable, Phase 3

Postmenopause

8 Actively Recruiting

Phase 2, Not Applicable, Phase 1

Aromasin Reviews: What are patients saying about Aromasin?

5Patient Review

3/19/2022

Aromasin for Advanced Breast Cancer Progression Post-Antiestrogen Therapy

Aromasin is by far the best treatment for high estrogen that I have tried in my years of heavy steroid use. It's helped me stay pain-free, without any joint issues or lethargy, and has allowed me to make gains in the gym.

4Patient Review

6/8/2014

Aromasin for Hormone Receptor Positive Postmenopausal Early Breast Cancer After Adjuvant Tamoxifen

Along with Aromasin for post-breast cancer care, I started taking kelp to help with the joint pain side effects. It's been a big help! If you're experiencing similar issues, this could be worth looking into.

2.7Patient Review

4/26/2016

Aromasin for Hormone Receptor Positive Postmenopausal Early Breast Cancer After Adjuvant Tamoxifen

I'm six weeks in on this medication, and I've found that it's really difficult for me to fall-and stay- asleep. Additionally, I sometimes have chest discomfort and have to take a few deep breaths to feel normal. Hot flashes like crazy during the first few hours after taking are another issue I've had to deal with. My appetite is off and I am not hungry at normal times of day; as a result, my glucose readings are all over the place. Not sure how long I will stay on this med before trying a different one.

2.3Patient Review

7/13/2017

Aromasin for Prevention of Breast Cancer

I had significant problems with bone pain that led to many sleepless nights. After a year of this and no improvement, I've switched to Tamoxifen in the hopes that it will be more effective.

2.3Patient Review

10/31/2018

Aromasin for Hormone Receptor Positive Postmenopausal Early Breast Cancer After Adjuvant Tamoxifen

After being on arimadex for 3 and 1/2 years, I experienced some serious side effects like joint pain, weight gain, and high blood pressure. I switched to aromasin last week but it's been giving me terrible stomach issues. My oncologist says that checking my hormone levels wouldn't be accurate, but I don't see how that makes sense. Plus, the medication is expensive. I'm done taking it for now and will just consider going back on it every once in a while. Quality of life is important to me.

View All Reviews

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Patient Q&A Section about aromasin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Aromasin a chemotherapy drug?

"Aromasin is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen for 2 to 3 years."

Answered by AI

How does Aromasin make you feel?

"Exemestane may make you feel nauseous or cause vomiting, but these symptoms generally improve over time."

Answered by AI

What does Aromasin do to the body?

"Aromasin prevents the enzyme aromatase from converting androgen into estrogen, thus reducing the amount of estrogen available to stimulate the growth of hormone receptor-positive breast cancer cells."

Answered by AI

Is Aromasin an estrogen blocker?

"Aromasin is a type of endocrine therapy that inhibits the aromatase enzyme. This lowers the level of the hormone estrogen in the body, which can starved cancer cells of their growth fuel. Aromasin is a pill that is taken orally."

Answered by AI

Clinical Trials for Aromasin

Have you considered Aromasin clinical trials? We made a collection of clinical trials featuring Aromasin, we think they might fit your search criteria.

Have you considered Aromasin clinical trials? We made a collection of clinical trials featuring Aromasin, we think they might fit your search criteria.