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What is Zerit
StavudineThe Generic name of this drug
Treatment SummaryZidovudine is a medication used to treat HIV. It works by blocking the virus’s ability to make copies of itself, slowing down the spread of the infection.
Zeritis the brand name
Zerit Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zerit
Stavudine
1994
45
Approved as Treatment by the FDA
Stavudine, commonly known as Zerit, is approved by the FDA for 1 uses including HIV .HIV
Used in combination with Stavudine to help manage Human Immunodeficiency Virus (HIV) Infections
Effectiveness
How Zerit Affects PatientsStavudine is a medication used to fight HIV-1. It works by blocking the HIV reverse transcriptase enzyme, which stops the virus from making copies of itself. Stavudine is turned into an active form in the body, which then interferes with the process of building new DNA for the virus. This prevents the virus from growing, as it needs this DNA to make copies of itself.
How Zerit works in the bodyStavudine works to stop HIV-1 from replicating. It does this by blocking reverse transcriptase, an enzyme that helps HIV-1 reproduce, from using its natural substrate, dGTP, and by preventing the incorporation of Stavudine into viral DNA.
When to interrupt dosage
The prescribed dosage of Zerit is contingent upon the diagnosed affliction. The measure of dosage is contingent upon the method of delivery (e.g. Oral or Capsule, gelatin coated - Oral) featured in the table beneath.Condition
Dosage
Administration
HIV
15.0 mg, , 20.0 mg, 30.0 mg, 40.0 mg, 1.0 mg/mL, 200.0 mg, 100.0 mg, 75.0 mg, 37.5 mg, 50.0 mg
, Powder, for solution - Oral, Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Powder, for solution, Capsule, Capsule - Oral, Solution, Solution - Oral, For solution - Oral, For solution, Capsule, extended release, Capsule, extended release - Oral
Warnings
There are 20 known major drug interactions with Zerit.Common Zerit Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Minor
Stavudine may increase the neurotoxic activities of Acepromazine.
Aceprometazine
Minor
Stavudine may increase the neurotoxic activities of Aceprometazine.
Acetophenazine
Minor
Stavudine may increase the neurotoxic activities of Acetophenazine.
Alimemazine
Minor
Stavudine may increase the neurotoxic activities of Alimemazine.
Amineptine
Minor
Stavudine may increase the neurotoxic activities of Amineptine.
Zerit Toxicity & Overdose RiskTaking too much stavudine (ZERIT) can lead to tingling, burning, numbness, or pain in the hands or feet, a potentially fatal build-up of acid in the blood, an enlarged and inflamed liver, and even liver failure.
Zerit Novel Uses: Which Conditions Have a Clinical Trial Featuring Zerit?
122 active clinical trials are in progress to evaluate the potential of Zerit for managing HIV infection.Condition
Clinical Trials
Trial Phases
HIV
146 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Zerit Reviews: What are patients saying about Zerit?
4Patient Review
7/3/2011 I've been on this medication for over two decades now and I'm starting to experience some side effects, like lower back pain and abdominal pain. Not sure if it's the Zerit or just age, but I might need to switch drugs soon.
1.7Patient Review
3/15/2010 This medication has caused facial disfigurement on both sides of my face.
Patient Q&A Section about zerit
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of stavudine?
"You may experience weakness, numbness, tingling, or burning pain in your hands or feet, nausea, vomiting, diarrhea, rash, or headache."
Answered by AI
Is Zerit still available?
"There are no brand or generic versions of stavudine available in the U.S."
Answered by AI
What is Zerit used for?
"ZERIT can be used in combination with other drugs to treat HIV-1 infection."
Answered by AI