Exercise for Ovarian and Endometrial Cancer Patients
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands or feet), and if there is any effect on inflammatory blood markers (the level of a certain marker in the blood that is associated with inflammation; redness and swelling).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with your doctor or the trial coordinators.
Is exercise safe for ovarian and endometrial cancer patients?
How does exercise as a treatment differ from other treatments for ovarian and endometrial cancer?
Exercise is unique because it focuses on improving physical activity levels to enhance body composition and reduce cancer risk, rather than using medication or surgery. It has been shown to improve survival rates and physical well-being, especially when combined with traditional treatments like chemotherapy.35678
What data supports the effectiveness of this treatment for ovarian and endometrial cancer patients?
Research shows that exercise can improve physical well-being and quality of life for women with ovarian cancer, and it may also be linked to better survival rates for endometrial cancer patients. Physical activity during and after cancer treatment is associated with less distress and improved psychosocial outcomes.235910
Who Is on the Research Team?
Christina M Dieli-Conwright, PhD
Principal Investigator
Dana-Farber Cancer Institute
Are You a Good Fit for This Trial?
This trial is for adults over 18 with stage III-IV ovarian or endometrial cancer who are starting first-line chemotherapy after surgery. They must be cleared by a doctor to do moderate-vigorous exercise, understand English, and consent to the study and blood draws. It's not for those with certain pre-existing conditions or uncontrolled illnesses that could affect participation.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a 16-week virtually supervised aerobic and resistance exercise program or home-based stretching
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Attention Control
- Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor