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Exercise for Ovarian Cancer

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Ovarian Cancer+5 MoreExercise - Other
Eligibility
18+
Female
What conditions do you have?
Select

Study Summary

This trial is testing whether a 16-week program of aerobic and resistance exercises, done at home with virtual supervision, is feasible for ovarian and endometrial cancer patients who are receiving first-line chemotherapy, and if it will improve leg function or reduce chemotherapy-induced numbness/tingling in the extremities.

Eligible Conditions
  • Ovarian Cancer
  • Endometrial Cancer
  • Stage III Ovarian Cancer
  • Endometrial Cancer Stage

Treatment Effectiveness

Effectiveness Progress

1 of 3

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1
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Study Objectives

2 Primary · 4 Secondary · Reporting Duration: 16 Weeks

16 Weeks
Enrollment Rate
Number of Participants with Treatment Related Adverse Events
PROMIS- Physical function
Proportion of patients completing the exercise intervention sessions.
Short Physical Performance Battery (SPPB)-Lower Extremity Function
16 weeks
Change in 6-minute walk distance

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Selinexor
1
Glutaminase Inhibitor IPN60090
1
Nivolumab

Trial Design

2 Treatment Groups

Attention Control
1 of 2
Exercise
1 of 2

Active Control

Experimental Treatment

30 Total Participants · 2 Treatment Groups

Primary Treatment: Exercise · No Placebo Group · N/A

Exercise
Other
Experimental Group · 1 Intervention: Exercise · Intervention Types: Other
Attention Control
Other
ActiveComparator Group · 1 Intervention: Attention Control · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 16 weeks

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor
1,016 Previous Clinical Trials
393,786 Total Patients Enrolled
38 Trials studying Ovarian Cancer
4,273 Patients Enrolled for Ovarian Cancer
Christina Dieli-Conwright, PhDPrincipal InvestigatorDana-Farber Cancer Institute
2 Previous Clinical Trials

Eligibility Criteria

Age 18+ · Female Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
, subject was excluded from the final analysis This subject was willing to have two blood draws for the study, but was excluded from the final analysis.
are essential for participation in a research study Being able to understand what you are agreeing to and willingness to sign an informed consent document are both essential for participating in a research study.
If you are 18 years old or older, your children will be excluded from this study because of the rarity of the disease.
for early-stage ovarian cancer did not improve long-term survival rates, a study has found
who received surgery and chemotherapy had a five-year survival rate of nearly 60 percent In the study, the five-year survival rate for newly diagnosed patients with stages III-IV ovarian or endometrial cancer who received surgery and chemotherapy was nearly 60 percent.
A physician's clearance is required to participate in moderate-vigorous intensity exercise.
Can read, write and understand English.
References

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