Valcyte

Cytomegalovirus Retinitis, Cytomegalovirus Infections, Acquired Immunodeficiency Syndrome + 4 more
Treatment
10 FDA approvals
20 Active Studies for Valcyte

What is Valcyte

ValganciclovirThe Generic name of this drug
Treatment SummaryValganciclovir hydrochloride is a medication manufactured by Roche that is used to treat cytomegalovirus infections. It is an antiviral drug that is converted to ganciclovir after it is taken orally. This conversion happens in the intestines and liver.
Valcyteis the brand name
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Valcyte Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Valcyte
Valganciclovir
2001
31

Approved as Treatment by the FDA

Valganciclovir, also called Valcyte, is approved by the FDA for 10 uses like prophylaxis of Cytomegalovirus infection and Cytomegalovirus (CMV) Infection .
prophylaxis of Cytomegalovirus infection
Cytomegalovirus (CMV) Infection
Acquired Immune Deficiency Syndrome (AIDS)
Cytomegalovirus Retinitis
Cytomegalovirus Infections
Lung Transplant
Acquired Immunodeficiency Syndrome
Cytomegalovirus Infections
Cardiac Transplant
Kidney Transplant

Effectiveness

How Valcyte Affects PatientsValganciclovir is an antiviral medication used to treat cytomegalovirus infections. It works by being converted into ganciclovir in the body, which then gets incorporated into the DNA of the virus and prevents it from replicating. This stops the virus from spreading and eventually causes it to die off.
How Valcyte works in the bodyValganciclovir is converted to ganciclovir in the body. Ganciclovir then binds to DNA in virus-infected cells, making it harder for the virus to replicate. This stops the virus from making copies of itself, and eventually it dies off. Ganciclovir works better on viruses than normal cells, so it can stop the virus without harming the body's cells.

When to interrupt dosage

The measure of Valcyte is contingent upon the determined illness, including Cardiac Transplant, Cytomegalovirus Infections and Cytomegalovirus Infections. Dosage can be found in the table below, corresponding to the procedure of application.
Condition
Dosage
Administration
Cytomegalovirus Infections
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Acquired Immunodeficiency Syndrome
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Kidney Transplant
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Cytomegalovirus Infections
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Lung Transplant
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Cardiac Transplant
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution
Cytomegalovirus Retinitis
, 450.0 mg, 50.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, For solution - Oral, For solution

Warnings

There are 20 known major drug interactions with Valcyte.
Common Valcyte Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Valganciclovir may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Valganciclovir may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Valganciclovir may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Valganciclovir may decrease the excretion rate of Almasilate which could result in a higher serum level.
Alogliptin
Minor
Valganciclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Valcyte Toxicity & Overdose RiskAn overdose of valganciclovir could cause increased kidney damage.
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Valcyte Novel Uses: Which Conditions Have a Clinical Trial Featuring Valcyte?

Currently, 68 active studies are assessing the potential of Valcyte to treat Cardiac Transplantation, Acquired Immunodeficiency Syndrome and Cytomegalovirus Infections.
Condition
Clinical Trials
Trial Phases
Cytomegalovirus Retinitis
0 Actively Recruiting
Cytomegalovirus Infections
4 Actively Recruiting
Phase 2
Kidney Transplant
35 Actively Recruiting
Phase 2, Phase 1, Not Applicable, Phase 4, Phase 3
Cytomegalovirus Infections
0 Actively Recruiting
Cardiac Transplant
8 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4
Acquired Immunodeficiency Syndrome
3 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Lung Transplant
18 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1

Valcyte Reviews: What are patients saying about Valcyte?

5Patient Review
4/4/2008
Valcyte for Cytomegalovirus Infection of the Retina in AIDS patients
I am a single lung transplant recipient and have been on this medication for a while. It is very costly, over $3300 per month, but it has been effective. I may have to stop taking it because I cannot afford it.
5Patient Review
7/4/2009
Valcyte for Treatment to Prevent Cytomegalovirus Disease
I used this medication for about six weeks after my transplant, but then I started vomiting and developed a rash, so I had to stop.
5Patient Review
5/21/2009
Valcyte for Prevention of CMV Infection Post Kidney Transplant
I had this treatment after an organ transplant. It was very effective in boosting my immune system.
5Patient Review
6/19/2010
Valcyte for Treatment to Prevent Cytomegalovirus Disease
So far, this treatment has been effective. I'm hoping it will be a long-term solution.
4.7Patient Review
12/27/2016
Valcyte for Treatment to Prevent Cytomegalovirus Disease
Valcyte has been great for me. I was worried about the fatigue, but it's manageable and the drug is really effective. No side effects whatsoever- would definitely recommend.
View All Reviews
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Patient Q&A Section about valcyte

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Valcyte?

"nausea, or vomiting

The possible side effects of the medication are: diarrhea, upset stomach, dizziness, loss of balance or coordination, drowsiness, unsteadiness, shaking (tremors), diarrhea, nausea, or vomiting."

Answered by AI

What is Valcyte used for?

"VALCYTE is used to treat CMV retinitis in people with AIDS. CMV retinitis is an infection of the eyes caused by the CMV virus."

Answered by AI

Is Valcyte an immunosuppressant?

"Valcyte is not an immunosuppressant, though it is often prescribed to people taking immunosuppressants after a transplant to prevent a CMV infection."

Answered by AI

How long can you take Valcyte?

"The recommended dose of Valcyte is two tablets taken twice a day for 21 days. Taking this medication for more than 21 days may increase your risk of developing side effects."

Answered by AI

Clinical Trials for Valcyte

Have you considered Valcyte clinical trials? We made a collection of clinical trials featuring Valcyte, we think they might fit your search criteria.
Have you considered Valcyte clinical trials? We made a collection of clinical trials featuring Valcyte, we think they might fit your search criteria.
Have you considered Valcyte clinical trials? We made a collection of clinical trials featuring Valcyte, we think they might fit your search criteria.
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