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What is Lamivudine
LamivudineThe Generic name of this drug
Treatment SummaryDideoxycytidine (ddC) is a medication used to treat HIV-1 and hepatitis B. It is a type of reverse transcriptase inhibitor, which means it stops the virus from replicating. It is a type of zalcitabine analog, which means it contains a sulfur atom instead of a carbon atom in the pentose ring.
Epiviris the brand name
Lamivudine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Epivir
Lamivudine
1995
178
Approved as Treatment by the FDA
Lamivudine, otherwise called Epivir, is approved by the FDA for 3 uses which include Chronic Hepatitis B Infection and HIV .Chronic Hepatitis B Infection
HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with Abacavir
HIV
Effectiveness
How Lamivudine Affects PatientsLamivudine is a drug that helps fight HIV-1 and hepatitis B. It works by preventing the virus from making more copies of its DNA. When Lamivudine is converted into its active form, it targets the virus’s reverse transcriptase enzyme, which is responsible for making DNA copies. Lamivudine interrupts the process of DNA copying, which keeps the virus from multiplying.
How Lamivudine works in the bodyLamivudine is a drug that stops the spread of HIV and hepatitis B by interrupting the replication process of the virus. It works by being converted into an active form inside the cells and then inserted into the virus' DNA, causing it to stop replicating.
When to interrupt dosage
The proposed dosage of Lamivudine is contingent upon the diagnosed state. The quantity of dosage fluctuates as per the delivery procedure outlined in the table below.Condition
Dosage
Administration
HIV
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Chronic Hepatitis B Infection
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Anti-Retroviral Agents
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
treatment failure
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Treatment Naive
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
HIV
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
There are 20 known major drug interactions with Lamivudine.Common Lamivudine Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Lamivudine may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Lamivudine may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Lamivudine may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Allylestrenol
Minor
Lamivudine may decrease the excretion rate of Allylestrenol which could result in a higher serum level.
Almasilate
Minor
Lamivudine may decrease the excretion rate of Almasilate which could result in a higher serum level.
Lamivudine Toxicity & Overdose RiskCommon side effects of taking this drug are headache, feeling sick, tiredness, blocked or runny nose, diarrhea, and coughing.
Lamivudine Novel Uses: Which Conditions Have a Clinical Trial Featuring Lamivudine?
At present, 125 active clinical trials are examining the effectiveness of Lamivudine in combating Chronic Hepatitis B.Condition
Clinical Trials
Trial Phases
treatment failure
0 Actively Recruiting
Anti-Retroviral Agents
0 Actively Recruiting
HIV
147 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Chronic Hepatitis B Infection
7 Actively Recruiting
Phase 3, Phase 2, Phase 1
Treatment Naive
0 Actively Recruiting
HIV
41 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
Lamivudine Reviews: What are patients saying about Lamivudine?
5Patient Review
1/28/2008 This treatment is effective with few side effects.
Patient Q&A Section about lamivudine
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are side effects of lamivudine?
"The following are symptoms of the flu: coughing, diarrhea, fatigue, headache, malaise, nasal symptoms, such as a runny nose, and nausea."
Answered by AI
What is lamivudine 100mg used for?
"This medication is meant to treat adults with chronic hepatitis b who also have liver disease that is still active, as shown by high ALT levels and/or evidence of liver inflammation and/or fibrosis."
Answered by AI
Is lamivudine an antibiotic?
"Lamivudine is an antiretroviral medication that reduces the amount of HIV in the body, slowing down or preventing damage to the immune system and reducing the risk of developing AIDS-related illnesses. It is also active against hepatitis b virus (HBV)."
Answered by AI
Can lamivudine cure hepatitis B?
"This medication is used to treat hepatitis b infection. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by slowing the growth of the virus, thereby decreasing liver damage caused by the virus. This medication is not a cure for hepatitis B and does not prevent the passing of hepatitis B to others."
Answered by AI