Acupuncture for Breast Cancer, Stage III

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Memorial Sloan Kettering Bergen, Montvale, NJ
Breast Cancer, Stage III+15 More
Acupuncture - Other
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether acupuncture can improve cognitive difficulties in patients diagnosed with cancer.

See full description

Eligible Conditions

  • Breast Cancer, Stage III
  • Stage III Prostate Cancer
  • Stage II Gynecologic Cancer
  • Stage II Prostate Cancer
  • Stage III Gynecologic Cancer
  • Stage I Colorectal Cancer
  • Gynecologic Cancers
  • Early Breast Cancer
  • Stage I Prostate Cancer
  • Breast Cancer, Stage II
  • Stage II Colorectal Cancer
  • Stage III Colorectal Cancer
  • Stage I Gynecologic Cancer

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Acupuncture will improve 1 primary outcome in patients with Breast Cancer, Stage III. Measurement will happen over the course of 16 weeks.

16 weeks
Cognitive difficulties as measured by the Functional Assessment of Cancer Therapy - Cognitive Function (FACT-Cog)

Trial Safety

Safety Estimate

2 of 3
This is better than 68% of similar trials

Side Effects for

Bi-Weekly Acupuncture
Serious unexpected
2%
Pain on needling
2%
This histogram enumerates side effects from a completed 2013 Phase 1 & 2 trial (NCT01305811) in the Bi-Weekly Acupuncture ARM group. Side effects include: Serious unexpected with 2%, Pain on needling with 2%.

Trial Design

2 Treatment Groups

Acupuncture
1 of 2
Sham Acupuncture (SA)
1 of 2
Experimental Treatment
Non-Treatment Group

This trial requires 48 total participants across 2 different treatment groups

This trial involves 2 different treatments. Acupuncture is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 2 and have already been tested with other people.

Acupuncture
Other
Sham Acupuncture (SA)
Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 16 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 16 weeks for reporting.

Closest Location

Memorial Sloan Kettering Bergen - Montvale, NJ

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 9 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
The patient must report that they have moderate or greater difficulty concentrating (scoring a "quite a bit" or "very much" on at least one of the two items that specifically assess concentration, item #20 on the EORTC QLQ-C30 instrument (version 3.0)) and difficulty remembering (scoring a "quite a bit" or "very much" on at least one of the two items that specifically assess memory, item #25 on the EORTC QLQ-C30 instrument (version 3.0)). show original
If you are finding that your memory or mental ability has declined since your cancer diagnosis, you are not alone show original
Do you think your mind isn't as sharp now as it was before your cancer diagnosis?
Do you feel like these problems have made it harder to function on your job or take care of things around the home?
Someone who wants to take part in this study must be willing to follow all the study procedures, including being randomly assigned to one of the two possible treatments: acupuncture or sham acupuncture. show original
English-speaking
You are at least 18 years old. show original
Diagnosis (breast, colorectal, prostate or gynecological cancer)
Had surgery, chemotherapy, or radiation therapy at least one month ago and are not currently receiving any other cancer treatments. show original

Patient Q&A Section

What are common treatments for colorectal cancer?

"Common treatments for the majority of patients with [colorectal cancer](https://www.withpower.com/clinical-trials/colorectal-cancer) include surgery, radiation therapy, chemotherapy and in certain cases hormonal therapy.\n\nIn a 2013 study, scientists found “inhibition of mitochondrial DNA replication by the DNA repair enzyme PARP1 is a common mechanism of action of anticancer drugs in cancer cells.”\n\n- Cancer and aging"

"Mauritius blue pigeon\n\nThe Mauritius blue pigeon ("Alectroenas nitidissima") is a species of bird in the family Columbidae. It is endemic to Mauritius." - Anonymous Online Contributor

Unverified Answer

What is colorectal cancer?

"Colorectal cancer is a serious and often fatal cancer in the United States. A colorectal cancer screening program has been shown to be the most cost-efficient tool available to reduce deaths and inequalities from colorectal cancer." - Anonymous Online Contributor

Unverified Answer

How many people get colorectal cancer a year in the United States?

"The number of American women diagnosed with colorectal cancer per year is estimated to be about one-third of the number of men, perhaps as many as 3.1 million. Furthermore, an estimated 5,500 women per year in the United States do not survive at 5 years owing to colorectal cancer. The National Center for Health Statistics should include colorectal cancer as a cause of death from all causes for women and the 5 most common sites of death for men and women who die of colorectal cancer." - Anonymous Online Contributor

Unverified Answer

What causes colorectal cancer?

"There is some evidence that some genes predispose individuals to colorectal cancer. The role of environment is not well understood. There may be common elements to colorectal cancer in North America and Europe. A more detailed understanding of the causes of colorectal cancer will help to determine the best management." - Anonymous Online Contributor

Unverified Answer

What are the signs of colorectal cancer?

"The diagnosis is more often based on symptoms in the cases without signs. We therefore recommend the clinical history based upon the patient’s experiences, examination symptoms and physical signs to be considered in diagnosis." - Anonymous Online Contributor

Unverified Answer

Can colorectal cancer be cured?

"A significant proportion of colorectal cancer develops in the presence of an identifiable premalignant lesion, and there is evidence suggesting that premalignant lesions are shed and shed again, thus the possibility that colon adenomas can be cured exists." - Anonymous Online Contributor

Unverified Answer

What does acupuncture usually treat?

"In the case of this study, acupuncture appears to be an effective treatment for the pain of the colon. The acupuncturist was very pleased with the treatment effect. When the acupuncture patient group experienced a cure in conjunction with a placebo, the acupuncturist was no longer pleased but he could not be convinced that a cure could have been achieved without real treatment. There appear to be at least two factors involved in acupuncture: physiologic arousal and psychological conditioning." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating colorectal cancer?

"There have been several advances in treating colorectal cancer, but most of them have not yet found their way to the clinic as adjuvant, neoadjuvant or metastatic treatment options for patients. The most exciting new option is the monoclonal antibody targeting L-selectin, PSMA and Pgp, although, the therapy would not have been used for many patients and therefore did not get into the regular treatment options." - Anonymous Online Contributor

Unverified Answer

How quickly does colorectal cancer spread?

"CRC can spread very quickly to the pelvic lymph nodes and later to the peritoneal cavity or in rare cases the omental nodes and the diaphragm. The peritoneal spread, however, has not been described. To determine an optimal interval for adjuvant chemotherapy following surgical resection for colorectal cancer requires study in a control arm. It is only reasonable, that we first establish the pattern of peritoneal dissemination in colorectal cancer and that we start adjuvant chemotherapy in peritoneal disease as soon as possible. Adjuvant chemotherapy should not start in the absence of peritoneal metastases." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in acupuncture for therapeutic use?

"Although the mechanism of acupuncture for therapeutic intervention of IBS is not clear, our study of the data reported by investigators in the specialty indicates that there is an abundance of research in the field of acupuncture research. Many acupuncture studies have found positive or significant results for IBS. The recent reports should be taken as an indication that the field of acupuncture is becoming more popular. However, because of the high methodological quality of some of these studies, the conclusions regarding the effectiveness of acupuncture for IBS may or may not be warranted." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets colorectal cancer?

"The average age of colorectal cancer patients is 70 years old. Colorectal cancer cases are diagnosed at an earlier age compared to mortality which is due to high rate of mortality among people with colorectal cancer. Among those colorectal cancer patients with a first diagnosis of colorectal cancer, 10% will die in the first year after diagnosis. The average time interval between diagnosis and death is 3.5 years. The incidence rate (defined as number of new cases per 100,000 population for each year) of colorectal cancer increases in the last decade (1996-2004)." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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