Acupuncture for Cancer-Related Cognitive Impairment

Recruiting at 7 trial locations

Age: 18+

Sex: Any

Trial Phase: Phase 2

Sponsor: Memorial Sloan Kettering Cancer Center

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Approved in 4 Jurisdictions This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

Duration: 16 weeks

48 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial is exploring whether acupuncture can help improve cognitive difficulties in cancer patients by stimulating the body to heal itself.

Research Team

Jun Mao, MD, MSCE

Principal Investigator

Memorial Sloan Kettering Cancer Center

Eligibility Criteria

This trial is for English-speaking adults over 18 who've finished initial cancer treatment at least a month ago and feel their memory or concentration has worsened since their diagnosis. They must not have active disease, recent acupuncture for cognition, certain psychiatric disorders, dementia, Parkinson's, or recent medication changes.

Inclusion Criteria

Must be English-speaking

I finished my initial cancer treatment over a month ago but may be on maintenance therapy.

I am willing to follow the study's procedures and accept being randomly assigned to real or sham acupuncture.

Exclusion Criteria

My disease is currently active.

I haven't started or changed any sleep, calm, or mood medications in the last 8 weeks.

I have been diagnosed with a brain disorder such as Alzheimer's or Parkinson's.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive acupuncture or sham acupuncture to assess its impact on cognitive difficulties

16 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• 16 week waiting period + optional Acupuncture
• Acupuncture
• Sham Acupuncture

Trial Overview The study tests if acupuncture can help with cognitive issues in cancer patients. Participants will be randomly assigned to receive either real acupuncture or sham (placebo) acupuncture. There's also an option of a waiting period followed by optional acupuncture.

Participant Groups

Group I: Wait-List Control Experimental Treatment 1 Intervention

This arm is Closed to accrual.

Group II: Acupuncture Experimental Treatment 1 Intervention

Group III: Sham Acupuncture (SA) Placebo Group 1 Intervention

Acupuncture is already approved in United States, European Union, China for the following indications:

Approved in United States as Acupuncture for:

• Pain management
• Hot flashes
• Fatigue
• Sleep disturbances
• Anxiety
• Depression
• Neuropathy

Approved in European Union as Acupuncture for:

• Pain management
• Hot flashes
• Fatigue
• Sleep disturbances
• Anxiety
• Depression

Approved in China as Acupuncture for:

• Pain management
• Hot flashes
• Fatigue
• Sleep disturbances
• Anxiety
• Depression
• Neuropathy

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials

1,998

Recruited

602,000+