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Behavioural Intervention

Meditation for Depression

N/A

Recruiting

Led By Olga Tymofiyeva, PhD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline/randomization and 12 weeks after baseline/randomization

Awards & highlights

Study Summary

This trial will test if meditation can improve depression in teens by increasing the strength of a brain structure and reducing depression symptoms.

Who is the study for?

This trial is for teens aged 14-18 with depression, who are under a healthcare provider's care and can use Zoom for remote participation. They must not have significant medical or mental health conditions other than depression or anxiety, not be on certain medications, without MRI contraindications like metal implants, and not currently practicing mindfulness.Check my eligibility

What is being tested?

The study tests if meditation training (TARA) affects brain connectivity and reduces depression in adolescents. It compares changes in the putamen region of the brain and self-rated depression symptoms between those receiving TARA and an active control group using psycho-education.See study design

What are the potential side effects?

Since this trial involves meditation training rather than medication, traditional side effects are minimal to none. However, participants may experience emotional discomfort when discussing personal issues during sessions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline/randomization and 12 weeks after baseline/randomization

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline/randomization and 12 weeks after baseline/randomization

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline/randomization and 12 weeks after baseline/randomization for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Putamen node strength

Secondary outcome measures

Change in Depression Symptoms

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Experimental: TARA TrainingExperimental Treatment1 Intervention

Behavioral: Training for Awareness, Resilience, and Action (TARA) This will be a 12-week group meditation training - Training for Awareness, Resilience, and Action (TARA)

Group II: Control: Psycho-EducationActive Control1 Intervention

Behavioral: Training for Awareness, Resilience, and Action (TARA) without the mindfulness meditation components This will be a 12-week group meditation training - Training for Awareness, Resilience, and Action (TARA) without the mindfulness meditation components

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

TARA

2014

N/A

~30

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,506 Previous Clinical Trials

15,238,435 Total Patients Enrolled

71 Trials studying Depression

28,708 Patients Enrolled for Depression

Olga Tymofiyeva, PhDPrincipal InvestigatorUniversity of California, San Francisco

3 Previous Clinical Trials

181 Total Patients Enrolled

2 Trials studying Depression

160 Patients Enrolled for Depression

Media Library

TARA (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05267340 — N/A

Depression Research Study Groups: Control: Psycho-Education, Experimental: TARA Training

Depression Clinical Trial 2023: TARA Highlights & Side Effects. Trial Name: NCT05267340 — N/A

TARA (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05267340 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this investigation include geriatric individuals?

"According to the regulations of this medical trial, adolescents between 14 and 18 years old may be eligible for inclusion."

Answered by AI

Is the application process for this clinical trial still accepting participants?

"According to the details provided by clinicaltrials.gov, this research project is currently open for recruitment. It was initially posted on February 8th 2023 and edited as recently as June 1st 2023."

Answered by AI

What is the scale of this clinical trial in terms of participants?

"Affirmative, clinicaltrials.gov lists this study as actively enrolling participants. It was published on February 8th 2023 and last edited on June 1st 2023. The trial is seeking 120 volunteers from one medical facility."

Answered by AI

Might I be a suitable candidate for this research project?

"This study requires 120 adolescents between the ages of 14 and 18 with a history of depression. In addition to being male or female, they must have a RADS-2 T-score greater than 50 (as judged by the physician) and be fluent in English. Participants should also possess an up-to-date Medical History form from NCCIH Version 1.0, lack any major medical/psychiatric conditions other than their depressive disorder (which is allowed but not required), currently receive care from either primary or mental health professionals, own access to technology such as smartphones, tablets or computers that can support "Zoom" software for"

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2

2023. "Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05267340.