TeleHealth Resistance Exercise for Breast Cancer
(THRIVE-65 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast cancer to receive all of their planned chemotherapy according to schedule and at the planned dose.
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop taking your current medications, but it does exclude those with medical conditions or medications that would prevent participation in an exercise program. It's best to discuss your specific medications with the trial coordinators.
Is TeleHealth Resistance Exercise for Breast Cancer safe for humans?
Research on exercise programs for breast cancer patients, including home-based and virtual interventions, suggests they are generally safe and can improve physical fitness and quality of life. These studies did not report significant safety concerns, indicating that such exercise programs are well-tolerated by participants.12345
How does the THRIVE treatment differ from other treatments for breast cancer?
What data supports the effectiveness of the treatment TeleHealth Resistance Exercise for Breast Cancer?
Research shows that telehealth-based exercise programs can significantly improve physical activity, muscle strength, fatigue, and quality of life in breast cancer patients compared to usual care. This suggests that such programs are beneficial as part of a comprehensive treatment for breast cancer.457910
Who Is on the Research Team?
Jennifer Ligibel, MD
Principal Investigator
Dana-Farber Cancer Institute
Nathan Berger, MD
Principal Investigator
Case Western Reserve University/University Hospitals Cleveland
Kathryn Schmitz (contact), PhD, MPH
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
Women over 65 with stage I-III invasive breast cancer, BMI of 18-50 kg/m2, starting chemotherapy for curative intent can join. They must be able to walk and understand English. Excluded are those highly active in the past 3 years, with dementia, substance abuse issues, on weight-loss meds or diets that conflict with the trial's diet.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Baseline visit to collect measurements, questionnaires, memory test, functional movement and strength testing, and physical activity assessment
Treatment
Participants are randomized to either the THRIVE Exercise and Diet Intervention or the Health Education and Support Program during chemotherapy
Follow-up
Follow-up visit up to 4 weeks after the completion of chemotherapy to repeat measurements and questionnaires
What Are the Treatments Tested in This Trial?
Interventions
- Health Education Support Program
- THRIVE
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor
University of Pittsburgh
Collaborator
Penn State University
Collaborator
National Cancer Institute (NCI)
Collaborator
Case Western Reserve University
Collaborator