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What is Qbrexza
GlycopyrroniumThe Generic name of this drug
Treatment SummaryGlycopyrronium, also known as NVA237 or glycopyrrolate, is a medication used to reduce secretions from sweat glands, the mouth, airways, and stomach. It is also used to reduce cardiac inhibitory reflexes and bronchoconstriction in Chronic Obstructive Pulmonary Disease (COPD). It was originally approved by the FDA in 1961 and is commonly prescribed as a first-line treatment for a variety of conditions, due to its wide therapeutic window.
Robinulis the brand name
Qbrexza Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Robinul
Glycopyrronium
1961
294
Effectiveness
How Qbrexza Affects PatientsGlycopyrronium is a type of medication typically used to treat long-term breathing problems. It is considered to have fewer side effects than other similar medications, but patients may still experience issues like worsening urinary retention, overheating, and blurry vision.
How Qbrexza works in the bodyGlycopyrronium blocks a certain kind of receptor in the body called muscarinic receptors. These receptors are found in the lungs, that help control breathing, and in the mouth, stomach, and sweat glands, that help control saliva and acid production. They also help control heart rate. When glycopyrronium blocks these receptors, it reduces the secretion of saliva, stomach acid, and sweat, and helps to prevent slow heart rates.
When to interrupt dosage
The recommended dosage of Qbrexza is contingent upon the diagnosed condition, such as Peptic Ulcer, Neurological Conditions and Drooling. The quantity of dosage can be found in the table below, contingent upon the delivery process (e.g. Capsule - Respiratory (inhalation) or Aerosol, metered).Condition
Dosage
Administration
Oral cavity
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
cardiac vagal inhibitory reflexes
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Bodily secretions
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Reflex, Trigeminocardiac
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Hyperhidrosis disorder
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Reflex, Trigeminocardiac
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Induction of anesthesia therapy
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
peripheral muscarinic effects
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Peptic Ulcer
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Drooling
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Increased upper airway secretion
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Emphysema
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Chronic Obstructive Pulmonary Disease
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Choking
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Neurological Conditions
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Chronic Bronchitis
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
General Surgery
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Cerebral Palsy
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Rapid Anticholinergic Effect Desired
, 1.0 mg, 2.0 mg, 0.2 mg/mL, 1.5 mg, 0.05 mg, 0.044 mg, 0.32 mg/mL, 1.0 mg/mL, 0.009 mg, 0.4 mg/mL, 0.0156 mg, 0.025 mg/mL, 0.024 mg/mg, 0.5 mg/mL, 0.0072 mg, 0.043 mg, 0.046 mg, 0.0083 mg/pump actuation, 0.0082 mg/pump actuation, 1.7 mg
, Tablet, Oral, Tablet - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Oral, Liquid - Oral, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Solution - Respiratory (inhalation), Solution - Intramuscular; Intravenous, Cloth, Cloth - Topical, Topical, Injection, solution - Intramuscular; Intravitreal, Intramuscular; Intravitreal, Aerosol, Aerosol - Respiratory (inhalation), Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Warnings
Qbrexza ContraindicationsCondition
Risk Level
Notes
Ulcerative Colitis
Do Not Combine
Uterine Inertia
Do Not Combine
Ulcerative Colitis
Do Not Combine
Myasthenia Gravis
Do Not Combine
Arterial Occlusive Diseases
Do Not Combine
Cardiovascular Physiological Phenomena
Do Not Combine
Pulse Frequency
Do Not Combine
Therapeutic procedure
Do Not Combine
Paralytic Ileus
Do Not Combine
Open-angle glaucoma
Do Not Combine
Uropathy Obstructive
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Glycopyrronium may interact with Pulse Frequency
Common Qbrexza Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Glycopyrronium is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Glycopyrronium is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Glycopyrronium is combined with Eluxadoline.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Glycopyrronium.
Secretin human
Major
The therapeutic efficacy of Secretin human can be decreased when used in combination with Glycopyrronium.
Qbrexza Toxicity & Overdose RiskOverdosing on Chlorpromazine may cause flushing, fever, rapid heartbeat, constipation, difficulty urinating, trouble seeing close up, light sensitivity, dilated pupils, nausea, vomiting, dizziness, and feeling faint. Treatment includes providing supportive care and potentially using a catheter for urinary retention or providing cardiovascular support, airway maintenance, ventilation, or neostigmine. The lowest toxic dose of Chlorpromazine in mice is 570 mg/kg and in rats is 709 mg/kg, while the intraperitoneal LD50 in mice is 90 mg/kg and in rats is 196 mg/kg
Qbrexza Novel Uses: Which Conditions Have a Clinical Trial Featuring Qbrexza?
164 active trials are currently underway to assess the potential of Qbrexza in treating Chronic Obstructive Pulmonary Disease (COPD), modulating cardiac vagal inhibitory reflexes and aiding General Surgery.Condition
Clinical Trials
Trial Phases
Oral cavity
0 Actively Recruiting
Rapid Anticholinergic Effect Desired
0 Actively Recruiting
Reflex, Trigeminocardiac
0 Actively Recruiting
Reflex, Trigeminocardiac
0 Actively Recruiting
Emphysema
12 Actively Recruiting
Phase 3, Phase 4, Phase 1, Phase 2, Not Applicable
peripheral muscarinic effects
0 Actively Recruiting
Chronic Bronchitis
5 Actively Recruiting
Not Applicable, Phase 3, Phase 4
Induction of anesthesia therapy
0 Actively Recruiting
Drooling
1 Actively Recruiting
Early Phase 1
Hyperhidrosis disorder
0 Actively Recruiting
Neurological Conditions
0 Actively Recruiting
Cerebral Palsy
1 Actively Recruiting
Not Applicable
Increased upper airway secretion
0 Actively Recruiting
cardiac vagal inhibitory reflexes
0 Actively Recruiting
Chronic Obstructive Pulmonary Disease
100 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Bodily secretions
0 Actively Recruiting
Choking
13 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 1
Peptic Ulcer
2 Actively Recruiting
Not Applicable, Phase 4
General Surgery
1 Actively Recruiting
Not Applicable
Qbrexza Reviews: What are patients saying about Qbrexza?
5Patient Review
12/17/2019 This cleansing method has been working great for me. I don't use it every day, but rather every few days as needed. This has helped to avoid any negative side effects.
5Patient Review
12/12/2019 This treatment is effective and quick-working. I noticed results after only a couple of days, with no negative side effects.
4.3Patient Review
8/4/2019 I've been using this product for a while and it's helped me a lot. I would recommend washing your hands thoroughly after application to avoid any negative side effects. The only downside is that it seems to be slowly becoming less effective over time, which is concerning.
4Patient Review
6/11/2019 This product is effective, but the side effects are really tough to deal with. My mouth and nose are so dry that I can barely stand it. Everything tastes horrible, and now I'm constipated on top of everything else. If you can stomach the side effects, this might be a good option for you. But personally, I'd rather try something else.
3.7Patient Review
8/5/2019 I didn't like this treatment because it caused really bad dry mouth. It was so uncomfortable and made it hard to eat or talk. The only plus side is that it helped keep my underarms dry.
3Patient Review
6/7/2019 The side effects were so bad that I only ended up using it once. My mouth was extremely dry, making it hard to swallow or talk. I also had urinary retention and difficulty urinating. It's a plus that I didn't sweat that day, but the other problems weren't worth it.
3Patient Review
11/21/2019 My son experienced a lot of the listed side effects after using this treatment for over a month. They were especially severe in regards to his vision. I contacted the company and they were no help whatsoever.
2.3Patient Review
8/11/2020 After only two days of using this product, I started getting nosebleeds from dried-out sinuses. My hands and lips were also extremely dry and swollen. So, I stopped the treatment right away and asked my doctor for an alternative called Mira dry.
1Patient Review
5/22/2019 I cannot recommend miradry enough! It's been life-changing for me. I used to have such bad underarm sweating, and since my dermatologist started using it on me, I haven't had any problems at all.
1Patient Review
7/25/2019 Though this product did as it said and took away all sweat from my body, the side effects are not worth it. I felt nauseous, had dry mouth and nose, blurred vision, and felt faint constantly. Do not recommend.
Patient Q&A Section about qbrexza
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can you use deodorant while using Qbrexza?
"You can only use deodorant once Qbrexza has dried completely."
Answered by AI
How long does it take Qbrexza to work?
"When will Qbrexza start to work?
Qbrexza will start to work within one to 1.5 hours of application. You may see an improvement in your sweating symptoms after just one week of using the product."
Answered by AI
How long should I use Qbrexza for?
"The studies found that Qbrexza wipes improved "sweating severity" by 25% to 30% (compared to 4% to 5% with placebo), and that measured sweat volume was reduced by 50% or more (in most patients.)"
Answered by AI
Do you need a prescription for Qbrexza?
"Qbrexza is a medication used to treat excessive underarm sweating. It is a topical anticholinergic medicine that is applied to the skin. It is for use in adults and children 9 years of age and older."
Answered by AI