Swallow Muscle Exercises for Swallowing Disorders
What You Need to Know Before You Apply
What is the purpose of this trial?
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is the swallow muscle exercising device safe for humans?
How is the Swallow Muscle Exercises treatment for swallowing disorders different from other treatments?
This treatment is unique because it combines advanced diagnostic techniques like manometry (pressure measurement) and fluoroscopy (X-ray imaging) with a specialized device for exercising swallow muscles, focusing on improving muscle strength and coordination, which is not typically addressed by standard treatments.12678
What data supports the effectiveness of the treatment Swallow Muscle Exercises for Swallowing Disorders?
The use of high-resolution pharyngeal manometry (HRM) with impedance can help assess swallowing function by measuring pressure changes during swallowing, which complements traditional methods like videofluoroscopy. Additionally, isometric progressive resistance oropharyngeal therapy has been shown to improve swallowing function, suggesting that similar exercises could be beneficial for swallowing disorders.1291011
Who Is on the Research Team?
Reza Shaker, MD
Principal Investigator
Medical College of Wisconsin
Are You a Good Fit for This Trial?
This trial is for adults aged 18 to 90 with difficulty swallowing (dysphagia) but normal esophageal muscle function tests. It's not for those under 18, recent head and neck cancer patients, people allergic to lidocaine or barium, pregnant or lactating women, medically unstable individuals, those unable to use a swallow muscle exerciser even with help, cognitively impaired persons, or patients with certain muscle and neuromuscular diseases.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Study
Baseline studies conducted using concurrent HRM/Impedance and digital video-fluoroscopy in upright and supine positions
Exercise Regimen
Participants undergo s-RED assisted or sham exercise three times a day for six weeks
Post-Exercise Study
Studies repeated post-exercise to compare baseline and exercise results
Follow-up
Participants are monitored for safety and effectiveness after the exercise regimen
What Are the Treatments Tested in This Trial?
Interventions
- Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
- Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medical College of Wisconsin
Lead Sponsor