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Cricoid Pressure for Acid Reflux (SE-GERD Trial)

N/A

Recruiting

Research Sponsored by Medical College of Wisconsin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up procedure (during simulated reflux perfusion of the esophagus)

Awards & highlights

SE-GERD Trial Summary

This trial aims to study how UES pressure can be improved to prevent pharyngeal reflux and to measure the effect of externally applied cricoid cartilage pressure on belch and swallow.

Who is the study for?

This trial is for GERD patients with regurgitation and supra-esophageal symptoms, based on American Gastroenterological Association guidelines. It's not for those under 20 or over 85, with a history of alcohol/drug abuse, certain GI/ENT/pulmonary diseases, inability to consent, pregnancy, cancer treatments history, or Lidocaine allergy.Check my eligibility

What is being tested?

The study tests if applying pressure to the cricoid cartilage can prevent acid reflux into the throat by strengthening the upper esophageal sphincter (UES). The effect on swallowing and belching will also be observed to ensure these functions aren't negatively impacted.See study design

What are the potential side effects?

Potential side effects may include discomfort at the site of applied pressure. Since this intervention is non-invasive and does not involve medication ingestion, severe side effects are unlikely.

SE-GERD Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ procedure (during simulated reflux perfusion of the esophagus)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~procedure (during simulated reflux perfusion of the esophagus)

This trial's timeline: 3 weeks for screening, Varies for treatment, and procedure (during simulated reflux perfusion of the esophagus) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Endoscopic evidence of supra-esophageal reflux

SE-GERD Trial Design

1Treatment groups

Experimental Treatment

Group I: Patients with supra-esophageal gastroesophageal reflux diseaseExperimental Treatment1 Intervention

GERD patients with complaints of regurgitation and supra-esophageal symptoms

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Medical College of WisconsinLead Sponsor

610 Previous Clinical Trials

1,162,623 Total Patients Enrolled

Media Library

Externally Applied Cricoid Cartilage Pressure (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05695846 — N/A

Acid Reflux Research Study Groups: Patients with supra-esophageal gastroesophageal reflux disease

Acid Reflux Clinical Trial 2023: Externally Applied Cricoid Cartilage Pressure Highlights & Side Effects. Trial Name: NCT05695846 — N/A

Externally Applied Cricoid Cartilage Pressure (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05695846 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the upper limit of participants for this research endeavor?

"Affirmative. According to clinicaltrials.gov, this medical investigation is presently accepting patients; the trial was initially posted on January 29th 2014 and last updated on February 8th 2023. The study necessitates 90 participants from one site."

Answered by AI

Is this research effort accessible to individuals seeking treatment?

"According to information maintained on clinicaltrials.gov, this study is still recruiting participants. The trial was first published in January of 2014 and has been regularly updated as recently as February of 2023."

Answered by AI

Does this trial accept applicants who are in their later years?

"For this research, participants must be within the age range of 20 to 85. Additionally, 12 trials are available for minors and 61 studies have been designed specifically with seniors in mind."

Answered by AI