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Virus Therapy

SPOTFIRE Arm for Acute Respiratory Infection (RADIATE Trial)

N/A

Recruiting

Led By Christopher Payette, MD

Research Sponsored by Christopher Payette

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up study enrollment through ed visit discharge, up to 24 hours

Awards & highlights

RADIATE Trial Summary

This trial aims to see if using a rapid test to identify the virus causing acute respiratory infections in the emergency department can help reduce unnecessary antibiotic use. The study will enroll patients with respiratory symptoms and use a

Who is the study for?

The RADIATE trial is for adults over 18 who visit the emergency department with symptoms of an acute respiratory illness lasting less than two weeks. They must be able to consent and have at least one symptom like cough, sneezing, or fever. There's no mention of exclusion criteria.Check my eligibility

What is being tested?

This study tests a rapid PCR test called SPOTFIRE R Panel in the emergency department to quickly identify viral infections causing respiratory illness, aiming to reduce unnecessary antibiotic use by providing accurate diagnosis.See study design

What are the potential side effects?

Since this trial involves diagnostic testing rather than medication or therapy, there are no direct side effects from the intervention itself.

RADIATE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ study enrollment through ed visit discharge, up to 24 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~study enrollment through ed visit discharge, up to 24 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and study enrollment through ed visit discharge, up to 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Antibiotic Use

Secondary outcome measures

Emergency Department Length of Stay

Patient Confidence in Diagnosis

Provider Confidence in Diagnosis

+1 more

RADIATE Trial Design

1Treatment groups

Experimental Treatment

Group I: SPOTFIRE ArmExperimental Treatment1 Intervention

The intervention involves the use of a rapid point-of-care multiplex PCR test to identify viral etiology in patients with acute respiratory illness. This approach aims to provide timely and accurate diagnostic information to guide treatment decisions. Specimen samples will be collected by research staff at the time of ED presentation by NPAAS. Upon collection, the sample will be promptly prepared for testing on the SPOTFIRE R Panel device. In this trial, all providers will view Spotfire results before prescribing antibiotics ; failure to so so will be a protocol violation.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Christopher PayetteLead Sponsor

BioMérieuxIndustry Sponsor

58 Previous Clinical Trials

42,030 Total Patients Enrolled

Christopher Payette, MDPrincipal InvestigatorGeorge Washington University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment process still open for individuals interested in participating in this trial?

"According to details on clinicaltrials.gov, this investigation is currently in search of eligible candidates. The trial was initially made public on March 12th, 2024 and underwent its latest revision on April 5th, 2024."

Answered by AI

What is the largest group size allowed to enroll in this research study?

"Indeed, the details on clinicaltrials.gov affirm that this medical investigation is actively seeking suitable candidates. The trial was initially published on March 12th, 2024, and recently revised on April 5th, 2024. It aims to recruit a total of 200 participants from a single designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Department (RADIATE)

Christopher Payette 2024. "Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Department (RADIATE)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06271655.

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