Otrexup

Polymyositis, Uveitis, Prophylaxis against graft versus host disease + 27 more
Treatment
20 Active Studies for Otrexup

What is Otrexup

MethotrexateThe Generic name of this drug
Treatment SummaryMethotrexate is a drug that works by blocking certain enzymes needed for cell growth and division. It is often used to treat inflammation caused by arthritis, or to control cell division in certain types of cancer, such as breast cancer and non-Hodgkin's lymphoma. It is only prescribed if first line treatments have failed or the patient is unable to tolerate them. Methotrexate was first approved by the FDA in 1953.
Methotrexateis the brand name
image of different drug pills on a surface
Otrexup Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methotrexate
Methotrexate
1953
137

Effectiveness

How Otrexup Affects PatientsMethotrexate stops specific enzymes from producing compounds needed for cell growth, reducing inflammation. It is usually taken once a week, but should not be taken daily. It is important to take the right amount of methotrexate, as it has a narrow range of effectiveness.
How Otrexup works in the bodyMethotrexate blocks the enzymes that help create the building blocks for cells to divide. This stops cells from multiplying, which reduces inflammation in conditions like rheumatoid arthritis. Additionally, methotrexate creates a buildup of certain molecules in the body, which helps stimulate anti-inflammatory action.

When to interrupt dosage

The amount of Otrexup is contingent upon the diagnosed affliction, including Uveitis, Polymyositis and nonleukemic meningeal cancer. The dosage is dictated by the process of administration featured in the table below.
Condition
Dosage
Administration
Uveitis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Acute Lymphoblastic Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Takayasu Arteritis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Arthritis, Juvenile
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Multiple Sclerosis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Lupus
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Medically induced abortion
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Crohn's Disease
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Acute Promyelocytic Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Gestational Trophoblastic Disease
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Hematopoietic stem cells
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Polymyositis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Chemotherapy
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Psoriasis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Lymphoma, Non-Hodgkin
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Dermatomyositis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Breast Cancer
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Rheumatoid Arthritis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis

Warnings

Otrexup has two contraindications and should not be taken when afflicted by the conditions indicated in the table below.Otrexup Contraindications
Condition
Risk Level
Notes
Non Neoplastic Condition
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Methotrexate may interact with Pulse Frequency
There are 20 known major drug interactions with Otrexup.
Common Otrexup Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abetimus
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Acteoside.
Aldosterone
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Aldosterone.
Otrexup Toxicity & Overdose RiskThe toxic dose in rats is 135mg/kg and in mice is 146mg/kg. Symptoms of an overdose may include a decrease in white blood cells, platelets, and red blood cells, mouth sores, nausea, vomiting, stomach ulcers, and bleeding from the digestive tract. If someone overdoses on this drug, they should be treated with glucarpidase and not leucovorin for 2 hours before or after the glucarpidase treatment.
image of a doctor in a lab doing drug, clinical research

Otrexup Novel Uses: Which Conditions Have a Clinical Trial Featuring Otrexup?

A total of 764 active studies are currently assessing the potential of Otrexup to manage Uveitis, Small Cell Lung Cancer and Soft Tissue Sarcoma.
Condition
Clinical Trials
Trial Phases
Acute Lymphoblastic Leukemia
120 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable, Early Phase 1, Phase 4
Non-Hodgkin's Lymphoma
123 Actively Recruiting
Phase 1, Phase 2, Early Phase 1, Not Applicable, Phase 3, Phase 4
Rheumatoid Arthritis
53 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Multiple Sclerosis
120 Actively Recruiting
Phase 3, Not Applicable, Phase 4, Phase 2, Phase 1, Early Phase 1
Lupus
57 Actively Recruiting
Phase 2, Phase 1, Not Applicable, Phase 3, Phase 4
Soft Tissue Sarcoma
58 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Bladder Cancer
105 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Early Phase 1
Hematopoietic stem cells
3 Actively Recruiting
Early Phase 1, Phase 1, Phase 2
Takayasu Arteritis
0 Actively Recruiting
Psoriasis
0 Actively Recruiting
Mycosis Fungoides
0 Actively Recruiting
Chemotherapy
3 Actively Recruiting
Phase 1, Phase 3, Not Applicable
Crohn's Disease
43 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Acute Promyelocytic Leukemia
0 Actively Recruiting
Breast Cancer
26 Actively Recruiting
Phase 2, Phase 1, Not Applicable
Sarcoma
0 Actively Recruiting
Lymphoma
5 Actively Recruiting
Phase 1, Phase 2
Gestational Trophoblastic Disease
0 Actively Recruiting
Pregnancy, Ectopic
0 Actively Recruiting
Polymyositis
4 Actively Recruiting
Phase 2, Phase 3

Otrexup Reviews: What are patients saying about Otrexup?

5Patient Review
4/28/2014
Otrexup for Severe Psoriasis that is Resistant to Treatment
I was doubtful at first, but after trying this medication out I was really pleased with how easy it is to use. This will save me a lot of time and hassle in the future.
5Patient Review
5/29/2014
Otrexup for Psoriasis associated with Arthritis
This treatment is much easier than Humira and/or Enbrel, and it also eliminates the gastrointestinal symptoms I had with oral MTX.
5Patient Review
9/26/2015
Otrexup for Rheumatoid Arthritis
I'm so glad I decided to go with Otrexup instead of Resuvo after my doctor told me about both options. The injector is much easier to use, and the medication itself is pain-free and convenient. I'll continue using it for as long as possible before having to switch to more expensive biologics.
5Patient Review
9/19/2014
Otrexup for Psoriasis associated with Arthritis
This is much easier to tolerate than the tablets, and even easier to administer than my Humira injections given my arthritis.
5Patient Review
7/9/2014
Otrexup for Chronic Joint Inflammatory Disease in Children and Young Adults of Unknown Cause
Doing this treatment at home saved me a lot of time and money.
View All Reviews

Patient Q&A Section about otrexup

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Otrexup used for?

"Otrexup (methotrexate) Injection is a drug used to manage severe, active rheumatoid arthritis (RA) (ACR criteria), or children with active polyarticular juvenile idiopathic arthritis (pJIA), who have had an insufficient therapeutic response to, or are intolerant of, other drugs."

Answered by AI

Where do you inject Otrexup?

"Otrexup is an auto-injector that is given only once per week and that must be injected into the abdomen or thigh."

Answered by AI

What does Otrexup cost?

"When comparing prices, please note that some retailers include shipping and handling fees in the advertised price.

The cost of a 1.6 milliliter supply of Otrexup subcutaneous solution (10 mg/0.4 mL) varies depending on the pharmacy, but is around $734. This price is for cash paying customers only and does not include insurance plans. When comparing prices, be aware that some retailers include shipping and handling fees in the advertised price."

Answered by AI

What class of drug is Otrexup?

"Otrexup is a drug that is used to treat cancer. It is part of a group of drugs called antineoplastics, which are drugs that kill cancer cells."

Answered by AI

Clinical Trials for Otrexup

Have you considered Otrexup clinical trials? We made a collection of clinical trials featuring Otrexup, we think they might fit your search criteria.
Have you considered Otrexup clinical trials? We made a collection of clinical trials featuring Otrexup, we think they might fit your search criteria.
Have you considered Otrexup clinical trials? We made a collection of clinical trials featuring Otrexup, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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