What is Natesto
TestosteroneThe Generic name of this drug
Treatment SummaryTestosterone is a male sex hormone used to treat conditions caused by low or absent testosterone levels in the body. Testosterone works by activating certain genes in the body which are responsible for the development of male reproductive organs and secondary sex characteristics. Testosterone was first isolated and synthesized in 1935.
Androdermis the brand name
Natesto Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Androderm
Testosterone
1995
90
Approved as Treatment by the FDA
Testosterone, commonly known as Androderm, is approved by the FDA for 12 uses including Gonadotrophin releasing hormone deficiency and Hypogonadism .Gonadotrophin releasing hormone deficiency
Helps manage Gonadotrophin releasing hormone deficiency
Hypogonadism
Helps manage Idiopathic Hypogonadotropic Hypogonadism
Orchitis
Helps manage Orchitis
Hypergonadotropic Hypogonadism
Helps manage Hypergonadotropic Hypogonadism
Hypothalamo-pituitary disorder
Helps manage Hypothalamo-pituitary disorder
Hypogonadotropic hypogonadism
Breast
Used to treat inoperable, metastatic Breast cancer in combination with Testosterone enanthate
Orchidectomy
Helps manage Orchidectomy
1 to 5 years post-menopausal
Used to treat 1 to 5 years post-menopausal in combination with Testosterone enanthate
Puberty, Delayed
Used to treat Puberty, Delayed in combination with Testosterone enanthate
vanishing testis syndrome
Helps manage vanishing testis syndrome
Torsion of testis
Helps manage Torsion of testis
Effectiveness
How Natesto Affects PatientsTestosterone helps to create the physical traits and organs associated with being male. How long it works can vary from person to person, but it typically lasts 10-100 minutes. This drug is considered safe, as normal testosterone levels in adult men range from 300-1000ng/dL. It's important to be aware that this drug can be transferred to children through skin contact, so patients should be warned of this risk.
How Natesto works in the bodyThe androgen receptor is a protein found in cells throughout the body. It binds to male hormones like testosterone, allowing them to enter the cell. The androgen receptor can then move into the nucleus, which activates the genes needed for male development. This includes the growth of organs like the prostate, penis, and scrotum, as well as secondary sexual characteristics like facial and body hair.
When to interrupt dosage
The recommended quantity of Natesto is contingent upon the diagnosed condition, such as Gonadotrophin releasing hormone deficiency, Orchidectomy and Orchitis. The amount of dosage shifts in line with the method of administration specified in the table below.Condition
Dosage
Administration
Orchidectomy
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Breast
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
1 to 5 years post-menopausal
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Hypogonadism
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
vanishing testis syndrome
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Orchitis
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Hypergonadotropic Hypogonadism
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Gonadotrophin releasing hormone deficiency
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Hypogonadotropic hypogonadism
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Puberty, Delayed
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Torsion of testis
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Hypothalamo-pituitary disorder
1.0 %, , 100.0 mg, 37.5 mg, 4.5 %, 50.0 mg, 200.0 mg, 5.5 mg, 0.1 mg/mg, 0.0125 mg/mg, 250.0 mg/mL, 12.5 mg, 0.05 mg/mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 100.0 mg/mL, 0.02025 mg/mg, 12.5 mg/pump actuation, 0.0405 mg/mg, 0.01 mg/mg, 0.00162 mg/mg, 75.0 mg, 30.0 mg/pump actuation, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 30.0 mg/mL, 30.0 mg, 200.0 mg/mL, 87.5 mg, 25.0 mg, 40.0 mg, 0.03 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 60.0 mg
, Buccal, Patch - Transdermal, Oral, Topical, Solution, Gel, metered, Gel, metered - Topical, Transdermal, Nasal, Solution - Topical, Gel, Patch, Gel - Topical, Gel - Transdermal, Pellet, Intramuscular, Pellet - Oral, Tablet, Solution - Transdermal, Pellet - Subcutaneous, Gel - Nasal, Injection, solution - Intramuscular, Capsule - Oral, Tablet - Buccal, Injection - Intramuscular, Gel, metered - Transdermal, Suspension, Subcutaneous, Pellet, implantable - Subcutaneous, Pellet, implantable - Parenteral, Gel, metered - Nasal, Pellet, implantable, Parenteral, Suspension - Intramuscular, Capsule
Warnings
Natesto ContraindicationsCondition
Risk Level
Notes
Breast Cancer
Do Not Combine
suspected pregnancy
Do Not Combine
Common Natesto Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Testosterone.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Testosterone.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Testosterone.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Testosterone.
Astemizole
Major
The metabolism of Astemizole can be increased when combined with Testosterone.
Natesto Toxicity & Overdose RiskThere is not much information on overdosing on topical testosterone products. However, if someone takes an injectable form of this drug, they may suffer a stroke. To treat an overdose, stop taking the testosterone, wash off any topical product with soap and water, and get medical help for any symptoms.
Natesto Novel Uses: Which Conditions Have a Clinical Trial Featuring Natesto?
Presently, 10 active clinical trials are analyzing the potential of Natesto to reduce the symptoms of Orchitis, Testicular Torsion and Hypothalamo-pituitary Dysfunction.Condition
Clinical Trials
Trial Phases
Breast
0 Actively Recruiting
Gonadotrophin releasing hormone deficiency
2 Actively Recruiting
Phase 1
Hypogonadotropic hypogonadism
0 Actively Recruiting
Torsion of testis
0 Actively Recruiting
vanishing testis syndrome
0 Actively Recruiting
Orchitis
0 Actively Recruiting
Hypogonadism
8 Actively Recruiting
Phase 1, Phase 4, Phase 2
Orchidectomy
0 Actively Recruiting
Puberty, Delayed
1 Actively Recruiting
Phase 1
Hypothalamo-pituitary disorder
0 Actively Recruiting
1 to 5 years post-menopausal
0 Actively Recruiting
Hypergonadotropic Hypogonadism
0 Actively Recruiting
Natesto Reviews: What are patients saying about Natesto?
5Patient Review
5/1/2018 I really disliked this medication. It was a huge hassle to have to use it three times a day, and I always forgot the dose during work hours. Additionally, the gel felt really weird in my nose and made it feel constantly stuffed up.
5Patient Review
3/20/2018 I felt more energetic pretty much as soon as I started taking this medication. Another big plus was that I started waking up on my own in the mornings, something I hadn't been able to do for years.
5Patient Review
10/21/2022 I'm on day three of using this product, and I've already noticed more energy and a higher sex drive. At the gym, I feel like I have the extra boost of youth.
5Patient Review
10/18/20155Patient Review
11/10/2017 I was using Axiron, but found it really inconvenient because I had to shower before each application. When I heard about Natesto, which is applied nasally, I was hesitant; however, it has been very easy to use and I'm much more pleased with it. It's not any cheaper, but the convenience factor once you get used to it makes it worth the price tag.
4.7Patient Review
5/30/2019 One downside to this treatment is that it can clog your nasal passages if you're not careful. Make sure to massage the area around your nose while using it for best results.
4.3Patient Review
8/6/2020 I've been using Natesto for almost three months now and I'm really happy with the results. My sex drive has increased, as well as my testicle size (which was decreased by other TRT treatments).
4.3Patient Review
3/14/2019 Out of all the options I've tried, this one is really the best.
4.3Patient Review
12/21/20154Patient Review
12/13/2018 I found this treatment to be much more effective than other options I've tried, like shots and axiron. There are also fewer ups and downs, which is great.
3.7Patient Review
6/10/2020 I have tried injections, androgel, axiron, pellets for my low testosterone levels with some success.
2.3Patient Review
2/1/2022 I had a tooth implant very close to the sinus wall, I suspect this product eroded the sinus wall exposing the implant and bone causing calcification and infection both in the sinus and gums.
Patient Q&A Section about natesto
What is Natesto used for?
"Natesto is a prescription medication that contains testosterone and is designed to treat adult males who have low or no testosterone due to certain medical conditions. Your healthcare provider will test your testosterone levels in your blood before you start and while you are using Natesto." - Anonymous Online Contributor
Unverified Answer
Is Natesto FDA approved?
"The US Food and Drug Administration approved Natesto Nasal Gel in May for adult males who have a deficiency or absence of the hormone testosterone due to conditions like primary hypogonadism or hypogonadotropic hypogonadism." - Anonymous Online Contributor
Unverified Answer
How long does it take for Natesto to work?
"Testosterone levels reach their appropriate level within 40 minutes of using Natesto. You may start seeing your symptoms improve soon after taking the medication. Use Natesto at the same time every day to keep your testosterone levels normal." - Anonymous Online Contributor
Unverified Answer
Is Natesto discontinued?
"Natesto has not been permanently discontinued in the United States." - Anonymous Online Contributor
Unverified Answer