What is Metaglip
GlipizideThe Generic name of this drug
Treatment SummaryGlipizide is a medication used to control blood sugar levels in people with type 2 diabetes. It was introduced in 1984 and is used in many countries such as Canada and the United States. Glipizide is in a group of drugs called sulfonylureas and is usually prescribed after the drug metformin. It works by stimulating the pancreas to make more insulin, which helps lower blood sugar levels. Glipizide is absorbed quickly and starts to work quickly, reducing the risk of long-term low blood sugar levels. Glipizide was approved by the FDA in 1994 and is available under the brand
Glucotrolis the brand name
Metaglip Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Glucotrol
Glipizide
1984
471
Approved as Treatment by the FDA
Glipizide, also called Glucotrol, is approved by the FDA for 1 uses such as Type 2 Diabetes .Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus
Effectiveness
How Metaglip Affects PatientsGlipizide is a drug used to lower blood sugar levels. It typically takes around half an hour to start working, and its effects can last for up to 24 hours. Over time, glipizide does not cause fasting insulin levels to rise, but it does help with the insulin response to meals. Its main action is to stimulate the pancreas to produce insulin, but it also has other effects in the body, such as increasing glucose uptake in muscles and the liver, and reducing lipolysis in the liver and fat cells. However, long-term use of glipizide can lead to a reduced effect on
How Metaglip works in the bodyType 2 diabetes is a condition where your body cannot regulate its blood sugar levels. Glipizide is a medication that helps people with this condition. It works by stimulating the pancreas to make more insulin, which helps the body absorb glucose from the bloodstream. Glipizide also increases the number and sensitivity of insulin receptors in the body, which helps the body use glucose better. This medication helps control blood sugar levels and reduce the risk of long-term health complications.
When to interrupt dosage
The prescribed dosage of Metaglip is contingent upon the diagnosed disorder. The dose fluctuates predicated on the mode of delivery (e.g. Tablet - Oral or Tablet, film coated - Oral) specified in the table below.Condition
Dosage
Administration
Type 2 Diabetes
2.5 mg, 5.0 mg, , 10.0 mg
Tablet - Oral, Tablet, film coated - Oral, Tablet, coated, Tablet, Oral, Tablet, film coated, , Tablet, extended release - Oral, Tablet, coated - Oral, Tablet, extended release, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
Metaglip has seven contraindications and should not be taken in union with any of the conditions described in the table below.Metaglip ContraindicationsCondition
Risk Level
Notes
Comatose
Do Not Combine
Toxoplasma Infections
Do Not Combine
Acute Coryza
Do Not Combine
Comatose
Do Not Combine
Comatose
Do Not Combine
Metabolic acidosis
Do Not Combine
Diabetic ketoacidosis with coma
Do Not Combine
Common Metaglip Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Minor
Glipizide may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Minor
Glipizide may increase the anticoagulant activities of (S)-Warfarin.
Abrocitinib
Minor
The metabolism of Abrocitinib can be decreased when combined with Glipizide.
Aclidinium
Minor
Glipizide may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Glipizide may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Metaglip Toxicity & Overdose RiskThe toxic dose of glipizide in rats has been found to be greater than 4000 mg/kg when taken orally and 1200 mg/kg when taken intraperitoneally. The lowest toxic dose for children is 379 μg/kg. Symptoms of an overdose may include loss of consciousness, seizures, or other neurological impairments due to severe hypoglycemia. Treatment for an overdose should include glucagon or intravenous glucose and monitoring for at least 24-48 hours as hypoglycemia may recur. Mild hypoglycemic symptoms without loss of consciousness or neurological findings should be treated with oral glucose.
Metaglip Novel Uses: Which Conditions Have a Clinical Trial Featuring Metaglip?
162 active clinical trials are examining the potential of Metaglip to manage Type 2 Diabetes.Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
174 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Early Phase 1, Phase 1, Phase 3
Metaglip Reviews: What are patients saying about Metaglip?
5Patient Review
11/26/2011 I've been taking this medication for over six years to manage my blood sugar levels and it has been very effective.
4.7Patient Review
5/13/20084Patient Review
7/5/2010 I haven't experienced any particularly worrisome side effects with this medication, which is why I decided to switch from Avandia.
1.7Patient Review
10/23/2008 I've had some issues with diarrhea since starting this medication, but nothing that I can't manage.
Patient Q&A Section about metaglip
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does metaglip have metformin?
"The medication Metaglip is a combination of the drugs glipizide and metformin, and is used to treat diabetes."
Answered by AI
What are the side effects of metaglip?
"The symptoms of the disease include nausea and vomiting, diarrhea, stomach pain or upset, joint or muscle aches pain, headache, dizziness, cold symptoms such as a stuffy nose, sneezing, or sore throat."
Answered by AI
What is metaglip used for?
"This medication for diabetes is a combination of 2 drugs (glipizide and metformin). It is used with a diet and exercise program to control high blood sugar in patients with type 2 diabetes."
Answered by AI
What is the generic name for metaglip?
"Metformin hydrochloride is an oral antihyperglycemic drug used in the management of type 2 diabetes.
The METAGLIP™ Tablets contain two oral antihyperglycemic drugs, glipizide and metformin hydrochloride, which are used to manage type 2 diabetes. Glipizide is an oral antihyperglycemic drug from the sulfonylurea class. Metformin hydrochloride is another oral antihyperglycemic drug used to manage type 2 diabetes."
Answered by AI