Junel 1.5/30

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Junel 1.5/30

What is Junel 1.5/30

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone (also known as norethindrone) is a synthetic hormone that acts like the natural hormone progesterone. It is a powerful hormone used in combination with other medications in various treatments such as contraception and hormone replacement therapy. It was first developed in 1951 and was used to treat irregular menstruation and endometriosis before it was used as an oral contraceptive in 1962.
Neconis the brand name
image of different drug pills on a surface
Junel 1.5/30 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Junel 1.5/30 Affects PatientsNorethisterone is a man-made pill used for birth control or to treat other hormone-related conditions. It acts like the hormone progesterone, but it is much more powerful. It works by changing how the cervix and uterus work, as well as by preventing hormones related to ovulation from working. Taking a combined oral contraceptive or a progestin-only pill may increase the risk of breast cancer, so patients should be aware of this and perform regular breast self-exams.
How Junel 1.5/30 works in the bodyNorethisterone is a progestin hormone that affects target cells in the reproductive tract, breast, pituitary, hypothalamus, skeletal tissue, and central nervous system. It prevents pregnancy by increasing the viscosity and content of cervical mucus, which makes it harder for sperm to enter the uterus. It also makes the endometrium inhospitable for fertilized eggs to implant. Norethisterone also suppresses the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary to prevent ovulation. When used for hormone replacement

When to interrupt dosage

The measure of Junel 1.5/30 is contingent upon the recognized condition, such as Atrophic, Fracture and Hormone Replacement Therapy. The quantity of dosage fluctuates, depending on the approach of delivery (e.g. Oral or Tablet) detailed in the table beneath.
Condition
Dosage
Administration
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Ovarian Failure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Postmenopausal Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Junel 1.5/30 has eight contraindications, hence it must not be taken in the presence of any of the situations given in the following table.Junel 1.5/30 Contraindications
Condition
Risk Level
Notes
active liver disease
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Junel 1.5/30.
Common Junel 1.5/30 Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Junel 1.5/30 Toxicity & Overdose RiskThe lowest toxic dose of oral contraceptives in mice has been found to be 6g/kg and the lowest dose causing an effect in adult women is 42mg/kg. There have been no serious reports of ill effects due to overdosing on oral contraceptives, including in children. Symptoms of overdose may include nausea and vomiting.
image of a doctor in a lab doing drug, clinical research

Junel 1.5/30 Novel Uses: Which Conditions Have a Clinical Trial Featuring Junel 1.5/30?

160 active studies are underway to investigate the efficacy of Junel 1.5/30 in providing Birth Control, Atrophic Endometrium and Low Testosterone therapy.
Condition
Clinical Trials
Trial Phases
Estrogen Deprivation Symptoms
0 Actively Recruiting
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Osteoporosis
39 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Endometriosis
30 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Low Testosterone
15 Actively Recruiting
Phase 1, Phase 4, Phase 2, Not Applicable
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Hormone Replacement Therapy
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Menopause
0 Actively Recruiting
Atrophic
5 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Fracture
0 Actively Recruiting
female castration
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Vasomotor System
0 Actively Recruiting
Endometriosis
1 Actively Recruiting
Phase 4
Ovarian Failure
2 Actively Recruiting
Not Applicable, Phase 1
Hormonal Contraception
0 Actively Recruiting

Junel 1.5/30 Reviews: What are patients saying about Junel 1.5/30?

4.7Patient Review
3/7/2014
Junel 1.5/30 for Birth Control
I love this product because it doesn't have any negative side effects like spotting or moodiness. The only downside is that it's lowered my sex drive.
4.7Patient Review
3/14/2019
Junel 1.5/30 for Birth Control
So far, so good. I haven't had any negative reaction to this medication and it's been really helpful.
4.3Patient Review
2/6/2013
Junel 1.5/30 for Painful Periods
I'm nearly done with my first pack, and it hasn't been as bad as I was expecting based on other people's reviews. I switched to this from Loestrin, which might be why it hasn't been too bad for me. I did have a few headaches, but that's normal for me anyway. I also wasn't getting my period on Loestrin, so we'll see how this goes. So far no extreme moodiness or depression, which is good. I took a pregnancy test early on because I was feeling a little nauseous, but everything came back negative
4.3Patient Review
4/7/2015
Junel 1.5/30 for Birth Control
This birth control was prescribed to me after taking Microgestion for awhile. It really helped get my body back on track; I lost the weight I gained on microgestion, got my sex drive back, and also wasn't moody anymore!
4Patient Review
1/19/2013
Junel 1.5/30 for Birth Control
I've been taking this pill for four months now with few issues. I occasionally get headaches, but that's normal for me anyway. Sometimes I spot depending on if I took the pill on time or not. I used to take tricyclin, and it made me an emotional wreck; however, with this medication, I'm only emotional around my period. So far, so good!
3.7Patient Review
12/5/2013
Junel 1.5/30 for Birth Control
I started taking Junel for cramps, irregularity, and heavy periods. The first time I got my period after starting the medication, the cramps were so bad that I couldn't move. However, they weren't as bad the second time around. I'll give it another month, but if the cramps don't improve I'll switch medications.
3.7Patient Review
4/11/2013
Junel 1.5/30 for Birth Control
I got my period after one week of taking Hummel, and it continued until I finished the pack. However, two weeks after finishing the pack, I was still bleeding. Additionally, I broke out like a teenager while on this medication. Overall, this pill was definitely not for me.
3Patient Review
5/22/2014
Junel 1.5/30 for Birth Control
I started Junel after my period stopped and I'm now on my second month. I've had two weeks of spotting, one week of what I consider to be my period (although it was five days earlier than last month), and a lot of breakouts. Overall, I don't really like this medication.
2.7Patient Review
5/1/2012
Junel 1.5/30 for Birth Control
2.3Patient Review
7/8/2013
Junel 1.5/30 for Abnormally Long or Heavy Periods
I used to take BeYaz and loved it, but my insurance stopped covering it. So my doctor switched me to this one--which I can't stand. I'm still bleeding a week after my period was supposed to end. Very dark discharge too. Not happy about this at all.
2Patient Review
7/25/2013
Junel 1.5/30 for Birth Control
I've been taking birth control for around ten years, and this is by far the worst kind I've tried. I constantly feel exhausted (to the point where napping is my primary activity), moody, and angry. Going back to Jolessa as soon as possible.
2Patient Review
5/6/2021
Junel 1.5/30 for Birth Control
I was on Lo Losterin for years and it worked great for me until my insurance stopped covering it. I've been taking Junel for 3 months now, and it has been absolute torture. I've gained weight, my breasts are incredibly tender, I'm moody and have night sweats. I also started getting migraines after starting this pill, which is something that has never happened to me in my life. I'm getting off of this medication as soon as possible.
1Patient Review
3/3/2013
Junel 1.5/30 for Birth Control
I've been using this medication for a little over a year now, and I constantly get urinary tract infections. They're extremely unpleasant and painful. However, this drug does keep my face clear and I never get my period, so that's something at least.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about junel 1.5/30

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Junel 1.5 30 cause weight gain?

"Weight gain is a rare side effect of Junel 1.5/30. If it does occur, it is usually not severe."

Answered by AI

What is Junel 1.5 mg 30 mcg tablet?

"This medication is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and norethindrone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month."

Answered by AI

What type of birth control is Junel 1.5 30?

"Junel 1.5/30 is a type of birth control that contains both estrogen and progesterone hormones. It is a monophasic birth control, which means that all of the active tablets contain the same amount of hormones."

Answered by AI

Is Junel 1.5 30 A good birth control?

"Overall, Junel Fe 1.5/30 (drospirenone / ethinyl estradiol) is considered to be a more effective form of birth control than other similar products.

Junel Fe 1.5/30 has an average rating of 4.8 out of 10 from a total of 126 ratings for the treatment of Birth Control. In general, reviewers thought that Junel Fe 1.5/30 was more effective than other similar products, but there were some negative experiences reported."

Answered by AI

Clinical Trials for Junel 1.5/30

Have you considered Junel 1.5/30 clinical trials? We made a collection of clinical trials featuring Junel 1.5/30, we think they might fit your search criteria.
Have you considered Junel 1.5/30 clinical trials? We made a collection of clinical trials featuring Junel 1.5/30, we think they might fit your search criteria.
Have you considered Junel 1.5/30 clinical trials? We made a collection of clinical trials featuring Junel 1.5/30, we think they might fit your search criteria.