Equetro

Chronic Pain, Bipolar Disorder, Bipolar Disorder + 6 more
Treatment
7 FDA approvals
20 Active Studies for Equetro

What is Equetro

CarbamazepineThe Generic name of this drug
Treatment SummaryCarbamazepine, also known as Tegretol, is a medication used to control seizures and treat pain caused by trigeminal neuralgia. It was first approved by the FDA in 1965 and is also prescribed to help manage the symptoms of bipolar disorder. It was the first anticonvulsant used to treat bipolar disorder.
Tegretolis the brand name
image of different drug pills on a surface
Equetro Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tegretol
Carbamazepine
1968
259

Approved as Treatment by the FDA

Carbamazepine, commonly known as Tegretol, is approved by the FDA for 7 uses like Bipolar Disorder and Partial Seizures With Secondary Generalization .
Bipolar Disorder
Partial Seizures With Secondary Generalization
Seizures
Bipolar Disorder
Acute Mania
Trigeminal Neuralgia
Helps manage Trigeminal Neuralgia (TN)
Chronic Pain
Helps manage Pain

Effectiveness

How Equetro Affects PatientsCarbamazepine is a drug used to treat seizures and facial nerve pain. It has also been found to reduce symptoms of bipolar disorder. Be aware that this drug has a small safety margin, so it is important to take the right dose. Additionally, some people with a certain genetic makeup (the HLA-B*1502 gene) can be more likely to suffer from skin reactions if they take this drug.
How Equetro works in the bodyCarbamazepine is used to treat seizures and bipolar disorder. Its exact mechanism is not fully understood, but it is thought to work by limiting the activity of nerve cells and decreasing pain signals in the brain. It works by binding to sodium channels and preventing action potentials, which stop the nerve from firing. In some cases, resistance to this drug can occur due to changes in metabolism caused by certain genotypes.

When to interrupt dosage

The prescribed measure of Equetro is subject to the identified condition, like Partial Seizures With Secondary Generalization, Bipolar Disorder and Trigeminal Neuralgia. The magnitude of dosage fluctuates as per the methodology of delivery featured in the table beneath.
Condition
Dosage
Administration
Syndrome
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Trigeminal Neuralgia
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Bipolar Disorder
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Partial Seizures With Secondary Generalization
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Bipolar Disorder
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Restless Legs Syndrome (RLS)
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Chronic Pain
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Acute Mania
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral
Seizures
, 100.0 mg, 200.0 mg, 400.0 mg, 300.0 mg, 100.0 mg/mL, 20.0 mg/mL, 10.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Oral, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Solution, Solution - Oral

Warnings

Equetro Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Bone Marrow
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Carbamazepine may interact with Pulse Frequency
There are 20 known major drug interactions with Equetro.
Common Equetro Drug Interactions
Drug Name
Risk Level
Description
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be increased when combined with Carbamazepine.
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Carbamazepine is combined with 2-Methoxyethanol.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be increased when combined with Carbamazepine.
5-androstenedione
Major
The metabolism of 5-androstenedione can be increased when combined with Carbamazepine.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Major
The risk or severity of adverse effects can be increased when Carbamazepine is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.
Equetro Toxicity & Overdose RiskThe lowest toxic dose of carbamazepine is 1920 mg/kg for women and 54 mg/kg for men. Signs and symptoms of an overdose on carbamazepine usually start to appear between 1-3 hours after ingestion and can include neuromuscular symptoms, cardiovascular effects, restlessness, tremor, dilated pupils, nystagmus, nausea, vomiting, urinary retention, dizziness, or drowsiness. Hyperreflexia or hyporeflexia may also occur. If you think you have overdosed on carbamazepine, contact your local poison control center and seek medical help. Make sure

Equetro Novel Uses: Which Conditions Have a Clinical Trial Featuring Equetro?

179 active clinical trials are being conducted to investigate the potential of Equetro to manage Partial Seizures With Secondary Generalization, Trigeminal Neuralgia and Restless Legs Syndrome (RLS).
Condition
Clinical Trials
Trial Phases
Bipolar Disorder
0 Actively Recruiting
Syndrome
3 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Partial Seizures With Secondary Generalization
1 Actively Recruiting
Not Applicable
Bipolar Disorder
1 Actively Recruiting
Phase 4
Trigeminal Neuralgia
0 Actively Recruiting
Chronic Pain
175 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Acute Mania
0 Actively Recruiting
Restless Legs Syndrome (RLS)
1 Actively Recruiting
Not Applicable
Seizures
2 Actively Recruiting
Phase 3

Equetro Reviews: What are patients saying about Equetro?

5Patient Review
10/16/2014
Equetro for Bipolar Disorder in Remission
This medication is easy to take and it really helps with my mood swings. The only downside is that it affects my sodium levels.
5Patient Review
2/14/2011
Equetro for Bipolar I Disorder with Most Recent Episode Mixed
This medication has quickly and effectively helped me with my bipolar disorder. I've only been taking it for a month, and I'm already seeing great results. The side effects are manageable, too; when I first started taking it, I was a little tired, but that went away after a week or two.
5Patient Review
10/27/2008
Equetro for Bipolar Disorder in Remission
This medication has been incredibly effective for me. I haven't had a single manic episode since starting it, and I couldn't be happier with the results.
5Patient Review
7/17/2010
Equetro for Facial Nerve Pain
This drug helped me to achieve a better mood, though I did experience constipation as a side effect.
5Patient Review
2/5/2008
Equetro for Bipolar Disorder in Remission
4.3Patient Review
5/3/2010
Equetro for Bipolar I Disorder with Most Recent Episode Mixed
My daughter has been on this medication since June, and it has done wonders for her. She loves being on it because she says she feels better now; remembers to take it every day all by herself. The only two problems we've encountered are weight gain and one episode of dizziness when we were increasing her dosage (we decreased the dosage again and that solved the issue). Otherwise, we've been problem-free. YAY!
4.3Patient Review
6/19/2010
Equetro for Bipolar I Disorder with Most Recent Episode Mixed
This drug has been a total game-changer for me. It's helped limit my bipolar episodes significantly. If I miss even just one dosage, I start having racing thoughts of catastrophe within hours.
4Patient Review
11/24/2007
Equetro for Mania associated with Bipolar Disorder
3.7Patient Review
9/23/2014
Equetro for Nerve Pain
I've tried more than 30 different medications for my rapid cycle bipolar disorder, and this is the only one that's worked for me. I was a little tired when increasing dosages, but it's been worth it because my mood swings have decreased, reading thoughts have decreased, depression has decreased, mania has decreased.
2Patient Review
12/1/2017
Equetro for Mania associated with Bipolar Disorder
I was started on 100mg at bedtime by my PDoc. I've been taking it for two weeks now, and she wanted to get me up to 200mg within that time; however, I found that I was wide awake until 2-3am after only four days. As a result, I'm going to try taking the medication in the morning instead.

Patient Q&A Section about equetro

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Equetro prescribed for?

"Equetro is an anticonvulsant medication used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Equetro is also used to treat bipolar disorder."

Answered by AI

What are the side effects of Equetro?

"This effect is harmless because your body has already absorbed the medication.

You may experience nausea, vomiting, dizziness, drowsiness, constipation, dry mouth, or unsteadiness. If you experience any of these effects for an extended period of time, or if they worsen, talk to your doctor or pharmacist. It is normal for an empty tablet shell to appear in your stool, as your body has already absorbed the medication."

Answered by AI

Is Equetro the same as carbamazepine?

"Equetro is a medication used to treat bipolar disorder. It comes in the form of extended-release capsules of 100 mg, 200 mg, or 300 mg of carbamazepine. Carbamazepine is an anticonvulsant that works by decreasing nerve impulses that cause seizures and pain."

Answered by AI

Is there a generic for Equetro?

"Currently, there is no therapeutically equivalent version of Equetro available for purchase in the United States. It is important to note that some online pharmacies may attempt to sell illegal generic versions of Equetro. These medications may be counterfeit and could pose serious health risks."

Answered by AI

Clinical Trials for Equetro

Have you considered Equetro clinical trials? We made a collection of clinical trials featuring Equetro, we think they might fit your search criteria.
Have you considered Equetro clinical trials? We made a collection of clinical trials featuring Equetro, we think they might fit your search criteria.
Have you considered Equetro clinical trials? We made a collection of clinical trials featuring Equetro, we think they might fit your search criteria.