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What is Darvocet
DextropropoxypheneThe Generic name of this drug
Treatment SummaryAcetaminophen, also known as Tylenol, is a widely-used pain relief medication. It can also be used to reduce fever. Acetaminophen is available in many different forms, such as syrup, regular tablets, effervescent tablets, injection, suppository, and other forms. It is also often combined with other drugs in over 600 over-the-counter allergy, cold, sleep, and pain relief medications. It is important to follow dosing guidelines when taking acetaminophen, as incorrect use can lead to fatal overdose or liver failure.
Propoxypheneis the brand name
Darvocet Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Propoxyphene
Dextropropoxyphene
1973
64
Approved as Treatment by the FDA
Dextropropoxyphene, also known as Propoxyphene, is approved by the FDA for 2 uses like Chronic Pain and Pain .Chronic Pain
Helps manage Pain
Pain
Helps manage Pain
Effectiveness
How Darvocet Affects PatientsAcetaminophen has been found to reduce fever and pain, but does not reduce inflammation. It does not interfere with the body's uric acid balance like some other painkillers, and it does not stop blood clotting or make it harder for platelets to form clots. Allergic reactions to acetaminophen are rare.
How Darvocet works in the bodyAcetaminophen is thought to reduce pain by blocking an enzyme called cyclooxygenase (COX). This enzyme is involved in the production of pain-causing chemicals called prostaglandins. Acetaminophen does not block COX in all parts of the body, so it does not have the same anti-inflammatory effects as NSAIDs. It is also believed to work on brain centers that regulate body temperature, causing you to sweat and lose heat. The exact way acetaminophen works is still not fully understood.
When to interrupt dosage
The measure of Darvocet is contingent upon the diagnosed affliction, such as Pain, Spasm and Inflammation. The amount of dosage also relies on the approach of administration detailed in the table beneath.Condition
Dosage
Administration
Chronic Pain
, 65.0 mg, 100.0 mg, 50.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral
Warnings
Darvocet ContraindicationsCondition
Risk Level
Notes
Hypercarbia
Do Not Combine
Asthma
Do Not Combine
Mental Depression
Do Not Combine
Intestinal Pseudo-Obstruction
Do Not Combine
Asthma
Do Not Combine
Common Darvocet Drug Interactions
Drug Name
Risk Level
Description
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Major
The risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Dextropropoxyphene.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Dextropropoxyphene.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Dextropropoxyphene.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Dextropropoxyphene.
Darvocet Toxicity & Overdose RiskAcetaminophen is toxic in large doses and can cause kidney damage, low blood sugar, low platelet count, and liver failure. In rare cases, it has been linked to cancer in female rats. It can also cause chromosome disruption at high doses, but no evidence of this has been seen in humans. Acetaminophen has not been linked to fertility issues, but it is still categorized as a pregnancy category C drug, meaning it has shown adverse effects in animals. It can be found in breast milk in small amounts and should be used cautiously by nursing mothers.
Darvocet Novel Uses: Which Conditions Have a Clinical Trial Featuring Darvocet?
698 active studies are currently in progress to investigate the efficacy of Darvocet in alleviating Chronic Pain, Rheumatoid Arthritis and Allergic Symptoms.Condition
Clinical Trials
Trial Phases
Chronic Pain
142 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Darvocet Reviews: What are patients saying about Darvocet?
5Patient Review
2/19/2014 I found this to be the most effective pain medication I've ever tried. My doctor was very surprised that it was no longer available on the market.
5Patient Review
12/3/2012 Darvocet-N 100 is the only medication I've found that doesn't make me nauseous, have abdominal discomfort, or go into anaphylactic shock (as I'm allergic to Codiene). Dealing with all the medication is tough, but this at least makes it manageable.
5Patient Review
1/18/2013 This treatment has been life-changing for me. It's helped me to walk and live again.
5Patient Review
12/29/2012 I found this treatment to be successful and hope there is something similar on the market now.
5Patient Review
3/9/2013 This is by far the best pain medication I've ever taken. Most others give me terrible rashes and itchiness, but this one doesn't.
Patient Q&A Section about darvocet
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What has replaced Darvocet?
"The drugs most commonly used as replacements for Darvocet are Buprenorphine and Suboxone."
Answered by AI
Why did Darvocet get recalled?
"The FDA has recalled the popular painkillers Darvocet and Darvon because they pose an unreasonable risk of heart problems."
Answered by AI
Do they still make the drug Darvocet?
"Propoxyphene, one of the most commonly prescribed medications in America, has been removed from the market following a thorough review by the FDA which concluded that the risks associated with propoxyphene outweigh the benefits."
Answered by AI
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