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What is Dyanavel Xr
AmphetamineThe Generic name of this drug
Treatment SummaryAmphetamine is a highly-restricted controlled drug that was discovered over 100 years ago. It is made up of the chemical alpha-methylphenethylamine and is composed of two forms of isomers, dextro- and levo-isomers. It was originally used to reduce drug-induced anesthesia and produce arousal and insomnia, and it was approved by the FDA in 1976. During World War II, amphetamine was used to help soldiers stay awake, and after the war, much of the surplus ended up in the black market, leading to its abuse.
Adderallis the brand name
Dyanavel Xr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Adderall
Amphetamine
1996
507
Approved as Treatment by the FDA
Amphetamine, also known as Adderall, is approved by the FDA for 2 uses which include Attention Deficit Hyperactivity Disorder and Narcolepsy .Attention Deficit Hyperactivity Disorder
Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Dextroamphetamine
Narcolepsy
Effectiveness
How Dyanavel Xr Affects PatientsAmphetamine affects the concentration of the neurotransmitters noradrenaline and dopamine in the brain in a dose and time-dependent way. It has been suggested to improve intelligence test scores and increase school performance, behavior, and demeanor for people with ADHD. However, it has also been linked to psychiatric dangers when misused, such as paranoia and depression.
How Dyanavel Xr works in the bodyAmphetamine has a similar structure to neurotransmitters like catecholamines. It works by attaching itself to sodium and chloride ions, which allow it to be taken in by the nerve terminals. It then competes with other neurotransmitters to get stored in the terminals, which causes them to be released into the synapse. This process is more effective in the d-isomer form of amphetamine. Amphetamine also works by limiting how much of the neurotransmitters are taken up and degraded by blocking the reuptake and monoamine oxidase enzymes. Additionally, it acts as a weak inhibitor of the mitochondrial enzyme MAO.
When to interrupt dosage
The proposed dosage of Dyanavel Xr is contingent upon the ascertained condition, like Disease, Chronic Pain and Attention Deficit Hyperactivity Disorder. The quantity of dosage can be found in the table below, in correlation with the mode of administration (e.g. Oral or Tablet - Oral).Condition
Dosage
Administration
Narcolepsy
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Depression
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Chronic Pain
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Warnings
Dyanavel Xr ContraindicationsCondition
Risk Level
Notes
Agitation
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Drug abuse
Do Not Combine
Hyperthyroidism
Do Not Combine
Hypertensive disease
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Amphetamine may interact with Pulse Frequency
Common Dyanavel Xr Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Amphetamine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Amphetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Amphetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Amphetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Amphetamine.
Dyanavel Xr Toxicity & Overdose RiskThe lethal dosage of amphetamine is 6.4mg/l. Overdosing can cause a range of symptoms, such as increased body temperature, shallow breathing, seizures, acidosis, kidney failure, liver damage, and loss of consciousness. There may also be neurological effects such as agitation, aggression, headache, and hallucinations. Cardiovascular issues such as abnormal heart rhythm, heart muscle problems, heart attack, and stroke may also occur. In the digestive system, overdose may cause abdominal pain, vomiting, diarrhea, cramping, lack of appetite, and bleeding. Animals studies have not found any evidence of cancer, chromosome damage, or infertility
Dyanavel Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Dyanavel Xr?
Currently, there are 710 active trials evaluating the potential of Dyanavel Xr to combat Depression, Disease and Narcolepsy.Condition
Clinical Trials
Trial Phases
Depression
698 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Early Phase 1, Phase 4
Chronic Pain
31 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Narcolepsy
10 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Dyanavel Xr Reviews: What are patients saying about Dyanavel Xr?
4.3Patient Review
11/6/2016 My daughter has Dysautonomia, as well as ADHD. Dyanavel has been a godsend for her; not only does it help with her ADHD symptoms, but it also acts as a vasoconstrictor, which has made a huge positive impact on my daughter's quality of life by minimizing her headaches and improving her GI system. The only problem we have is that the medication sticks to the pharmacy bottle and runs out days too soon, which is concerning.
3Patient Review
12/19/2017 At first, this medication was really effective. But now, I find that it makes me depressed. I'm not sure if it's the medication or if it's because taking it makes me feel like a failure.
Patient Q&A Section about dyanavel xr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does DYANAVEL XR last?
"The effects of DYANAVEL XR generally last for 13 hours after taking the medication."
Answered by AI
Is there a generic for DYANAVEL XR?
"While Dyanavel XR is an expensive drug used to treat ADHD, it is less popular than comparable drugs. There are no generic alternatives to Dyanavel XR currently."
Answered by AI
What is DYANAVEL XR used for?
"Amphetamine is a medication used to treat ADHD by changing the amounts of certain natural substances in the brain. It belongs to a class of drugs known as stimulants."
Answered by AI