Larin 24 Fe

Endometriosis, Low Testosterone, Osteoporosis + 16 more

Treatment

20 Active Studies for Larin 24 Fe

Treatment for

Endometriosis

What is Larin 24 Fe

NorethisteroneThe Generic name of this drug

Treatment SummaryNorethisterone is a synthetic progestin hormone used to treat menstrual problems, endometriosis, and contraception. It is a second-generation progestin, more potent than naturally-occurring progesterone, and is sold in combination with estrogen forms for hormone replacement therapy. It was first developed in 1951 in Mexico City and was not available for use as an oral contraceptive until 1962.

Neconis the brand name

Larin 24 Fe Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Necon

Norethisterone

1967

347

Effectiveness

How Larin 24 Fe Affects PatientsNorethisterone is a medication that can be taken by mouth to prevent pregnancy or treat other hormone-related conditions. It is a powerful progestin, meaning it acts similarly to the hormone progesterone, but more strongly. Norethisterone affects the pelvic area, cervical area, and endometrial area, as well as the hormones that help eggs mature and be released from the ovaries. Taking norethisterone may slightly increase the risk of developing breast cancer, so patients should be aware of this and do regular breast exams.

How Larin 24 Fe works in the bodyNorethisterone works in a few ways to prevent pregnancy. It thickens the mucus in the cervix, making it difficult for sperm to pass through. It also makes the lining of the uterus inhospitable to an embryo, preventing it from implanting and growing. Norethisterone also has a negative feedback effect on the hormones that control ovulation and follicular development, stopping those processes from occurring. When used for hormone replacement therapy, norethisterone helps to protect against overgrowth of the endometrium, which can lead to cancer. Finally, it has a low affinity for other steroid receptors,

When to interrupt dosage

The advised dosage of Larin 24 Fe is contingent on the diagnosed state, such as Atrophic, Fracture and Hormone Replacement Therapy. The measure of dosage is dependent on the mode of delivery (e.g. Oral or Tablet) featured in the table beneath.

Condition

Dosage

Administration

Atrophic

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Hot flashes

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Hormone Replacement Therapy

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

female castration

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Low Testosterone

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

hypoestrogenism

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Therapeutic procedure

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Fracture

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Ovarian Failure

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Postmenopausal Osteoporosis

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Vasomotor System

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Oral Contraceptives

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Hormonal Contraception

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Estrogen Deprivation Symptoms

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Menopause

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Endometriosis

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Birth Control

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Osteoporosis

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Endometriosis

0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg

Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Larin 24 Fe has eight counter-indications, and should not be administered in combination with the conditions enumerated in the following table.Larin 24 Fe Contraindications

Condition

Risk Level

Notes

active liver disease

Do Not Combine

Thrombophilia

Do Not Combine

Vaginal Hemorrhage

Do Not Combine

Malignant Neoplasms

Do Not Combine

Benign hepatic neoplasm

Do Not Combine

Breast Cancer

Do Not Combine

Thromboembolism

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Norethisterone may interact with Pulse Frequency

There are 20 known major drug interactions with Larin 24 Fe.

Common Larin 24 Fe Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Norethisterone.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Norethisterone.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.

Clomipramine

Major

The metabolism of Clomipramine can be increased when combined with Norethisterone.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Norethisterone.

Larin 24 Fe Toxicity & Overdose RiskThe lowest toxic dose of oral contraceptives in mice is 6g/kg, and the lowest toxic dose in women is 42mg/kg. Serious illness following an overdose of oral contraceptives is rare, but may include nausea and vomiting.

image of a doctor in a lab doing drug, clinical research

Larin 24 Fe Novel Uses: Which Conditions Have a Clinical Trial Featuring Larin 24 Fe?

160 active clinical trials are being conducted to evaluate the potential of Larin 24 Fe to provide Birth Control, Atrophic Uterine Conditions and Low Testosterone Levels.

Condition

Clinical Trials

Trial Phases

Endometriosis

32 Actively Recruiting

Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1

Osteoporosis

40 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3

Estrogen Deprivation Symptoms

0 Actively Recruiting

Oral Contraceptives

2 Actively Recruiting

Not Applicable

Therapeutic procedure

0 Actively Recruiting

Menopause

0 Actively Recruiting

Hormone Replacement Therapy

0 Actively Recruiting

Atrophic

6 Actively Recruiting

Phase 2, Phase 4, Not Applicable

Low Testosterone

15 Actively Recruiting

Phase 1, Phase 4, Phase 2, Not Applicable

Hot flashes

22 Actively Recruiting

Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1

Postmenopausal Osteoporosis

3 Actively Recruiting

Not Applicable, Phase 4

Birth Control

31 Actively Recruiting

Not Applicable, Phase 3, Phase 4, Early Phase 1

Fracture

0 Actively Recruiting

female castration

0 Actively Recruiting

hypoestrogenism

2 Actively Recruiting

Phase 4

Vasomotor System

0 Actively Recruiting

Endometriosis

1 Actively Recruiting

Phase 4

Ovarian Failure

2 Actively Recruiting

Not Applicable, Phase 1

Hormonal Contraception

0 Actively Recruiting

Patient Q&A Section about larin 24 fe

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of birth control is Larin 24 Fe?

"The Larin 24 Fe contraceptive consists of active tablets containing the progestin norethindrone acetate and the estrogen ethinyl estradiol, as well as placebo tablets containing ferrous fumarate. The ferrous fumarate serves no therapeutic purpose."

Answered by AI

Does Larin 24 Fe cause weight gain?

"The most common side effects people reported were headaches, yeast infections, nausea, menstrual cramps, breast tenderness, abdominal pain, mood changes, bacterial vaginitis, acne, irregular bleeding, and weight gain."

Answered by AI

What is Larin Fe generic for?

"Larin Fe is a combination birth control pill containing the female hormones progestogen and estrogen, as well as iron supplement tablets. It is used to prevent pregnancy in women who choose to use oral contraceptives as their method of contraception. Larin Fe is available in generic form."

Answered by AI

What are the side effects of Larin 24 Fe?

"These are some of the side effects that may occur when using this medication. Nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change may occur. Spotting or missed/irregular periods may also occur, especially during the first few months."

Answered by AI

Clinical Trials for Larin 24 Fe

Image of University of Colorado Department of Obstetrics & Gynecology in Aurora, United States.

Elagolix for Infertility

This trial is testing a new medication given by mouth to women with endometriosis who are trying to get pregnant through IVF. The main goal is to see if the medication can increase the chances

University of Colorado Department of Obstetrics & Gynecology (+4 Sites)Hugh Taylor, MD

Image of University of Michigan in Ann Arbor, United States.

My Pelvic Plan Website for Endometriosis

This trial aims to see if an online self-management program can help patients with Chronic Pelvic Pain feel better. The researchers believe that patients using the program will have less pain, better physical function, and

Waitlist Available

University of MichiganSara Till, MD

Image of University of Colorado Anschutz Medical Campus in Aurora, United States.

Desogestrel / Ethinyl Estradiol Pill for Birth Control

This trial aims to understand how differences in our DNA can affect how our bodies process hormones in birth control pills, potentially influencing their effectiveness in preventing pregnancy and causing different side effects in individuals. Participants will take

Waitlist Available

University of Colorado Anschutz Medical Campus (+1 Sites)Aaron M Lazorwitz, MD, PhD

Image of McLean Function Measurement Lab in Ottawa, Canada.

Repetitive Transcranial Magnetic Stimulation for Endometriosis

This trial aims to improve pain outcomes for Canadian women with endometriosis. It will test the effectiveness of a repetitive transcranial magnetic stimulation (rTMS) intervention for reducing pain in individuals

No Prior Treatment

McLean Function Measurement LabLinda McLean, PhD

Have you considered Larin 24 Fe clinical trials? We made a collection of clinical trials featuring Larin 24 Fe, we think they might fit your search criteria.

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Image of University of Central Florida in Orlando, United States.

Wrist/hand immobilization for Menstruation

"This trial aims to understand why females tend to get more hand and wrist injuries compared to males in sports. The study will look at the impact of hormones, such as those from birth control, on muscle

University of Central Florida

Image of University of Colorado Anschutz Medical Campus in Aurora, United States.

Transdermal Estradiol Patch +2 More for Menopause

"This trial aims to study how the decrease in estrogen during menopause affects artery health and body fat distribution in women. The researchers will investigate whether low estrogen levels lead to decreased artery function and increased fat in

Waitlist Available

University of Colorado Anschutz Medical CampusKerrie Moreau, PhD

Image of University of Kentucky in Lexington, United States.

Alendronate for Osteoporosis

This trial aims to address the issue of age-related bone loss, which is often overlooked in current osteoporosis treatments. The study compares the effectiveness of two drugs, Alendronate and Terip

Waitlist Available

University of KentuckyHartmut H Malluche, MD

Image of Hybl Sports Medicine and Performance Center in Colorado Springs, United States.

Hot Water Therapy for Menopause

Colorado Springs, CO

This trial is studying the effects of hot water therapy on menopausal women. The researchers want to see if taking hot baths for multiple days in a row can reduce hot flash symptoms and improve mood.

Hybl Sports Medicine and Performance CenterNathan Morris, PhD

Have you considered Larin 24 Fe clinical trials? We made a collection of clinical trials featuring Larin 24 Fe, we think they might fit your search criteria.

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Image of University of Arizona in Tucson, United States.

PhytoSERM for Hot Flashes

This trial is testing the effects of a supplement called PhytoSERM on menopausal symptoms in women. Participants will either take PhytoSERM pills or a placebo for 12 weeks. After

University of ArizonaFei Yin, PhDNeuTherapeutics

Image of Citruslabs in Santa Monica, United States.

Probiotic Supplement for Menopause Symptoms

Santa Monica, CA

This trial tests if a probiotic supplement can reduce menopause symptoms like hot flashes, night sweats, mood swings, etc. Participants take a test product or placebo daily and provide data on weight, waist, sleep, and symptoms.

Waitlist Available

Dietary Supplement

CitruslabsManeuver Marketing

Image of Planned Parenthood of Northern California in Berkeley, United States.

Ovaprene for Birth Control

This trial will study a new, non-hormonal contraceptive ring for safety, effectiveness, and acceptability.

Planned Parenthood of Northern California (+20 Sites)Christine Mauck, MDDaré Bioscience, Inc.

Image of St. Barnabas Woodlands in Pittsburgh, United States.

Denosumab +1 More for Osteoporosis

This trial aims to show that a new medication called Denosumab can help older adults who are weak and frail by improving their muscle health, strength, mobility, and overall function.

St. Barnabas Woodlands

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