6 for Moral Injury

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Moral Injury+1 More
Modified A-B-C: Working with Events, Thoughts, and Feelings - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test a brief, effective form of CPT against a control condition.

Eligible Conditions
  • Moral Injury

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: Baseline, 6-week, 3-month, 6-month

Baseline, 6-week, 3-month, 6-month
PTSD Checklist for DSM-5 (PCL-5) Change
Patient Health Questionnaire (PHQ-9) Change
The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) Change

Trial Safety

Safety Progress

1 of 3

Trial Design

16 Treatment Groups

6
1 of 16
2
1 of 16
3
1 of 16
12
1 of 16
10
1 of 16
13
1 of 16
4
1 of 16
7
1 of 16
9
1 of 16
14
1 of 16
5
1 of 16
11
1 of 16
8
1 of 16
15
1 of 16
16
1 of 16
1
1 of 16

Active Control

270 Total Participants · 16 Treatment Groups

Primary Treatment: 6 · No Placebo Group · N/A

6ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Patterns of Problematic Thinking · Intervention Types: Behavioral, Behavioral, Behavioral
2
Behavioral
ActiveComparator Group · 1 Intervention: Modified A-B-C: Working with Events, Thoughts, and Feelings · Intervention Types: Behavioral
3
Behavioral
ActiveComparator Group · 1 Intervention: Challenging Questions · Intervention Types: Behavioral
12ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Beliefs, Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
10ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Beliefs, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy) · Intervention Types: Behavioral, Behavioral, Behavioral
13ActiveComparator Group · 3 Interventions: Challenging Beliefs, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Patterns of Problematic Thinking · Intervention Types: Behavioral, Behavioral, Behavioral
4ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
7ActiveComparator Group · 3 Interventions: Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Patterns of Problematic Thinking, Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
9
Behavioral
ActiveComparator Group · 1 Intervention: Challenging Beliefs · Intervention Types: Behavioral
14ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Beliefs, Patterns of Problematic Thinking · Intervention Types: Behavioral, Behavioral, Behavioral
5
Behavioral
ActiveComparator Group · 1 Intervention: Patterns of Problematic Thinking · Intervention Types: Behavioral
11ActiveComparator Group · 3 Interventions: Challenging Beliefs, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
8ActiveComparator Group · 3 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Patterns of Problematic Thinking, Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
15ActiveComparator Group · 3 Interventions: Challenging Beliefs, Patterns of Problematic Thinking, Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral
16ActiveComparator Group · 5 Interventions: Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Beliefs, Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy), Patterns of Problematic Thinking, Challenging Questions · Intervention Types: Behavioral, Behavioral, Behavioral, Behavioral, Behavioral
1
Behavioral
ActiveComparator Group · 1 Intervention: Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 6-week, 3-month, 6-month

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,474 Previous Clinical Trials
2,741,424 Total Patients Enrolled
6 Trials studying Moral Injury
460 Patients Enrolled for Moral Injury
Rebecca Kaufman Sripada, PhD MSPrincipal InvestigatorVA Ann Arbor Healthcare System, Ann Arbor, MI

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 2nd, 2021

Last Reviewed: November 5th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
Utah100.0%
How old are they?
18 - 65100.0%
What site did they apply to?
VA Salt Lake City Health Care System, Salt Lake City, UT100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%