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Digital Weight Loss Intervention for Obesity and Type 2 Diabetes Risk (mLIFE Trial)

N/A
Waitlist Available
Led By Brie Turner-Mcgrievy
Research Sponsored by University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Must be between 18-65 years old
Must have no current use of medications that may impact blood glucose
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

mLIFE Trial Summary

This trial will use a digital weight loss intervention with or without social gaming to see if it produces more weight loss at 12 months than the same intervention without gaming, in 240 adults with overweight or obesity and 3+ type 2 diabetes risk factors.

Who is the study for?
This trial is for adults aged 18-65 with obesity or overweight, having a BMI of 25-49.9 kg/m2 and at least three risk factors for Type 2 diabetes but not diagnosed with it. Participants must own a smartphone, be willing to change their diet and exercise habits, and not be on medications affecting blood glucose or involved in other weight loss programs.Check my eligibility
What is being tested?
The study tests whether an app called mLIFE that includes social gaming features can help people lose more weight over a year compared to the same app without these features. The app provides podcasts, tips, self-regulation tools, and rewards supportive interactions aimed at reducing calorie intake and increasing physical activity.See study design
What are the potential side effects?
Since this intervention involves lifestyle changes through an app rather than medication, side effects are minimal but may include potential stress from dietary restrictions or increased physical activity.

mLIFE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 65 years old.
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I am not taking any medications that affect my blood sugar levels.

mLIFE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in body weight
Secondary outcome measures
Change in Kcals consumed a day
Change in minutes a week of moderate to vigorous physical activity (MVPA)

mLIFE Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Gamified mLIFE app groupExperimental Treatment3 Interventions
Participants allocated to this group will be provided with elements of social gaming and healthy competition within the mLIFE app.
Group II: standard mLIFE appActive Control3 Interventions
Participants in this group will receive the same intervention as the experimental group, but some features of the App will not facilitate gaming or competition.

Find a Location

Who is running the clinical trial?

University of South CarolinaLead Sponsor
211 Previous Clinical Trials
120,219 Total Patients Enrolled
31 Trials studying Obesity
8,675 Patients Enrolled for Obesity
Brie Turner-McgrievyPrincipal InvestigatorUniversity of South Carolina

Media Library

mLIFE app (self-regulation features) Clinical Trial Eligibility Overview. Trial Name: NCT05176847 — N/A
Obesity Research Study Groups: Gamified mLIFE app group, standard mLIFE app
Obesity Clinical Trial 2023: mLIFE app (self-regulation features) Highlights & Side Effects. Trial Name: NCT05176847 — N/A
mLIFE app (self-regulation features) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05176847 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has this experiment commenced enrollment of participants?

"Affirmative. According to details hosted on clinicaltrials.gov, this medical experiment - first posted on March 1st 2022 - is actively seeking participants. The goal of the trial is to recruit a total of 240 patients from a single site."

Answered by AI

What is the sample size of this experiment?

"Affirmative, the information posted on clinicaltrials.gov states that this research is actively enlisting patients. First announced on March 1st of 2022 and last edited April 18th, 240 participants are needed from a single medical centre."

Answered by AI

Are persons aged 45 or over admissible to this medical trial?

"Anyone aged between 18 and 65 is eligible to take part in this clinical trial."

Answered by AI

May I be accepted as a participant in this clinical experiment?

"This experiment requires the recruitment of 240 participants who suffer from type 2 diabetes and are aged between 18-65. Furthermore, they must meet certain prerequisites such as owning a smartphone with internet access, having 3 T2DM risk factors (ADA criteria), being free of major health or psychiatric issues, not participating in any weight loss programs, BMI within 25 to 49.9 kg/m2 range; all while abstaining from drugs or alcohol consumption and medications that may affect glucose levels."

Answered by AI

Who else is applying?

What site did they apply to?
University of South Carolina
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
The Mobile Lifestyle Intervention for Food and Exercise Study
Brie Turner-McGrievy 2022. "The Mobile Lifestyle Intervention for Food and Exercise Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05176847.
~97 spots leftby Sep 2025
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