Yoga & Meditation for Irritable Bowel Syndrome

Overseen By Basant Pradhan, MD

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: The Cooper Health System

Disqualifiers: Under 12, Over 21, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Approved in 1 Jurisdiction This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

Duration: 6 weeks

10 Participants Needed

Trial Summary

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators or your doctor.

What data supports the effectiveness of the treatment Yoga, Mindfulness Program, Meditation Program, Yoga Therapy for Irritable Bowel Syndrome?

Research shows that yoga and meditation can help reduce symptoms of irritable bowel syndrome (IBS), improve quality of life, and decrease pain and anxiety. Studies have found that these mind-body practices are effective in managing IBS symptoms and enhancing overall well-being. ^{1 2 3 4 5}

Is yoga and meditation safe for people with irritable bowel syndrome?

Research suggests that yoga and meditation are generally safe for people with irritable bowel syndrome and may even offer benefits for both physical and mental health. ^{2 6 7 8 9}

How is the Yoga and Meditation treatment for IBS different from other treatments?

Yoga and meditation for IBS is unique because it focuses on reducing stress and improving quality of life through mindfulness and relaxation techniques, rather than using medication. This treatment can be delivered virtually, making it accessible and convenient for patients, and it has shown effectiveness in managing symptoms like pain and bloating over both short and long-term periods. ^{1 2 10 11 12}

What is the purpose of this trial?

Irritable Bowel Syndrome (IBS) is the most common cause of recurrent abdominal pain in children. IBS is a functional gastrointestinal disorder that is linked to motor and sensory physiology, as well as the central nervous system, that presents as abdominal pain with abnormal defecation patterns. This discomfort leads to emotional stress, decreased quality of life, and anxiety. The study proposes that yoga and mindfulness will decrease anxiety and increase quality of life for patients with IBS. The aim of this study is to measure the impact of a brief, at-home, 6-week twice per week Standardized Yoga \& Meditation Program for Stress Reduction program on anxiety, IBS symptoms, and quality of life in children ages 12-21 diagnosed with IBS.

Research Team

Alla Kushnir, MD

Principal Investigator

The Cooper Health System

Eligibility Criteria

This trial is for adolescents aged 12-21 with any type of Irritable Bowel Syndrome (IBS) who are patients at Cooper Pediatric Gastroenterology in Voorhees or Camden, NJ. They must be able to access the internet to watch yoga videos and commit to completing at least 4 out of the 6 modules.

Inclusion Criteria

Subjects must be able to access the internet to be able to watch the yoga videos on Youtube

Patients of Cooper Pediatric Gastroenterology practice in Camden, NJ or Voorhees, NJ

Patients of Cooper Pediatric Gastroenterology practice in Voorhees, NJ

Exclusion Criteria

I am younger than 12 years old.

I am over 21 years old.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a 6-week, at-home, twice per week Standardized Yoga & Meditation Program for Stress Reduction

6 weeks

Online participation

Follow-up

Participants are monitored for changes in anxiety, IBS symptoms, and quality of life after the intervention

4 weeks

Treatment Details

Interventions

• Yoga

Trial Overview The study tests a Standardized Yoga & Meditation Program designed for stress reduction in young IBS patients. Over six weeks, participants will follow this program twice weekly at home, aiming to reduce anxiety and improve their quality of life.

Participant Groups

Group I: IBS Patients Doing Yoga Experimental Treatment 1 Intervention

All patients will fall under the arm of "IBS Patients Doing Yoga" and will follow the yoga videos that are assigned to them during the study. The participants are their own controls and their symptom changes will be recorded pre- and post-video watching and participation.

Who Is Running the Clinical Trial?

The Cooper Health System

Lead Sponsor

Trials

82

Recruited

35,600+

Findings from Research

This study will evaluate the effectiveness of an 8-week virtual yoga and meditation program for managing irritable bowel syndrome (IBS) symptoms, comparing it to an advice-only control group, with outcomes assessed at baseline, 4 weeks, and 8 weeks.

The trial will also assess feasibility through recruitment and retention rates, participant satisfaction, and safety, aiming to provide insights into the potential of virtual yoga as a therapeutic option for IBS.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Meditation and yoga for irritable bowel syndrome: study protocol for a randomised clinical trial (MY-IBS study). D'Silva, A., Marshall, DA., Vallance, J., et al.[2022]

Yoga has been shown to significantly reduce bowel symptoms, IBS severity, and anxiety in patients with irritable bowel syndrome (IBS), based on a systematic review of six randomized controlled trials involving 273 patients.

The review suggests that yoga may improve quality of life and physical functioning for IBS patients, and it appears to be a safe adjunctive treatment, as no adverse events were reported in the studies analyzed.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effect of Yoga in the Therapy of Irritable Bowel Syndrome: A Systematic Review. Schumann, D., Anheyer, D., Lauche, R., et al.[2018]

A systematic review of six randomized controlled trials involving patients with irritable bowel syndrome (IBS) found that mindfulness meditation significantly improved quality of life and reduced pain scores compared to control groups.

The mindfulness group showed a notable increase in spiritual awareness and a decrease in IBS symptom severity, indicating that mind-body interventions can be effective in managing IBS symptoms and enhancing overall well-being.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Meditation and Irritable Bowel Syndrome, a Systematic Review and Meta-Analysis. Baboș, CI., Leucuța, DC., Dumitrașcu, DL.[2022]

A short course of Preksha Dhyana (PD), a child-friendly meditation technique combined with yoga, significantly improved pain severity and anxiety in children with IBS, with 93% of participants experiencing pain improvement.

The PD program was successfully integrated into a busy pediatric office setting, showing high completion rates and cost-effectiveness without increasing overall healthcare utilization compared to traditional treatment approaches.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of Short Course of Preksha Dhyana for Functional Abdominal Pain Disorder in a Busy Pediatric Clinic. Mehta, V., Mehta, A., Patel, S., et al.[2021]

In an 8-week mindfulness-based stress reduction (MBSR) program involving 68 adults with irritable bowel syndrome (IBS), 71% of participants reported significant improvements in gastrointestinal symptoms and quality of life.

The study found that enhancing the 'Act with Awareness' aspect of mindfulness was the strongest predictor of these improvements, suggesting that focusing on the present moment can be particularly beneficial for individuals with IBS.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Mindfulness-based stress reduction improves irritable bowel syndrome (IBS) symptoms via specific aspects of mindfulness. Naliboff, BD., Smith, SR., Serpa, JG., et al.[2021]

The study will investigate the effects of Iyengar yoga on irritable bowel syndrome (IBS) symptoms in 60 participants aged 14-26, with a focus on clinical outcomes, quality of life, and psychospiritual functioning over a 6-week period.

It is hypothesized that participants practicing yoga will experience significant improvements in IBS symptoms and related factors, with mechanisms including reduced visceral sensitivity and better stress regulation contributing to these benefits.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Protocol for a randomized controlled study of Iyengar yoga for youth with irritable bowel syndrome. Evans, S., Cousins, L., Tsao, JC., et al.[2021]

A 6-week Iyengar yoga program significantly improved IBS symptoms and overall functioning in young adults (ages 18-26), with benefits in psychological distress, sleep quality, and fatigue, compared to a usual-care waitlist group of 22 participants.

While adolescents (ages 14-17) showed improved physical functioning, the overall benefits of yoga were more pronounced in young adults, suggesting that yoga may be more effective when tailored to the developmental stage of the participants.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Iyengar yoga for adolescents and young adults with irritable bowel syndrome. Evans, S., Lung, KC., Seidman, LC., et al.[2021]

In a study of 22 males with diarrhea-predominant irritable bowel syndrome (IBS), both yogic and conventional treatments significantly reduced bowel symptoms and state anxiety over 2 months.

The yogic intervention showed enhanced parasympathetic reactivity, suggesting a potentially better mechanism for managing IBS symptoms compared to conventional treatment, which improved gastric activity.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Yogic versus conventional treatment in diarrhea-predominant irritable bowel syndrome: a randomized control study. Taneja, I., Deepak, KK., Poojary, G., et al.[2022]

Yoga is shown to be an effective and safe therapy for Irritable Bowel Syndrome (IBS), outperforming pharmacological treatments and matching the effectiveness of dietary changes and moderate exercise, based on evidence from randomized controlled trials.

Improvements from yoga practice were noted in both physical health (like symptom severity and gastric motility) and mental health (including reductions in anxiety and depression), although the overall quality of evidence is limited due to variability in study designs and outcomes.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Yoga as a Therapy for Irritable Bowel Syndrome. D'Silva, A., MacQueen, G., Nasser, Y., et al.[2022]

A one-year follow-up study with 10 out of 13 original participants showed that Relaxation Response Meditation (RRM) significantly reduced IBS symptoms, including abdominal pain, diarrhea, flatulence, and bloating.

Continued practice of RRM led to further reductions in pain and bloating from the three-month follow-up to the one-year mark, indicating its effectiveness as a long-term treatment for IBS.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A one year follow-up of relaxation response meditation as a treatment for irritable bowel syndrome. Keefer, L., Blanchard, EB.[2019]

Hypnosis, used as an adjunct therapy for irritable bowel syndrome (IBS), has shown significant improvement in symptoms and quality of life for patients, with most experiencing lasting benefits after up to 12 sessions over 3 months.

The therapy focuses on 'gut-directed' techniques, teaching patients skills to control gut function, and incorporates lifestyle and psychological factors tailored to individual needs, enhancing its effectiveness.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Gut-directed hypnotherapy: the Manchester approach for treatment of irritable bowel syndrome. Gonsalkorale, WM.[2019]

A virtual Hatha yoga program significantly reduced IBS symptoms in participants, with a notable decrease in the IBS Symptom Severity Scale (IBS-SSS) by an average of 54.7 points, compared to a smaller change in the control group.

The yoga intervention also improved quality of life, fatigue, and perceived stress among participants, demonstrating its feasibility and safety, although it was not found to be superior to the advice-only control group in terms of overall IBS symptom reduction.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Meditation and Yoga for Irritable Bowel Syndrome: A Randomized Clinical Trial. D'Silva, A., Marshall, DA., Vallance, JK., et al.[2023]

References

1. England pubmed.ncbi.nlm.nih.gov

Meditation and yoga for irritable bowel syndrome: study protocol for a randomised clinical trial (MY-IBS study). [2022]

2. United States pubmed.ncbi.nlm.nih.gov

Effect of Yoga in the Therapy of Irritable Bowel Syndrome: A Systematic Review. [2018]

3. Switzerland pubmed.ncbi.nlm.nih.gov

Meditation and Irritable Bowel Syndrome, a Systematic Review and Meta-Analysis. [2022]

4. Switzerland pubmed.ncbi.nlm.nih.gov

Efficacy of Short Course of Preksha Dhyana for Functional Abdominal Pain Disorder in a Busy Pediatric Clinic. [2021]

5. England pubmed.ncbi.nlm.nih.gov

Mindfulness-based stress reduction improves irritable bowel syndrome (IBS) symptoms via specific aspects of mindfulness. [2021]

6. England pubmed.ncbi.nlm.nih.gov

Protocol for a randomized controlled study of Iyengar yoga for youth with irritable bowel syndrome. [2021]

7. United States pubmed.ncbi.nlm.nih.gov

Iyengar yoga for adolescents and young adults with irritable bowel syndrome. [2021]

8. Germany pubmed.ncbi.nlm.nih.gov

Yogic versus conventional treatment in diarrhea-predominant irritable bowel syndrome: a randomized control study. [2022]

9. United States pubmed.ncbi.nlm.nih.gov

Yoga as a Therapy for Irritable Bowel Syndrome. [2022]

10. England pubmed.ncbi.nlm.nih.gov

A one year follow-up of relaxation response meditation as a treatment for irritable bowel syndrome. [2019]

11. England pubmed.ncbi.nlm.nih.gov

Gut-directed hypnotherapy: the Manchester approach for treatment of irritable bowel syndrome. [2019]

12. United States pubmed.ncbi.nlm.nih.gov

Meditation and Yoga for Irritable Bowel Syndrome: A Randomized Clinical Trial. [2023]