Pharmacist Intervention for High Cholesterol
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to compare pharmacist-led care with usual care in managing high cholesterol for individuals with heart disease. The focus is on improving the use of cholesterol-lowering medications to prevent further heart problems. In the experimental group, a pharmacist will review participants' medical records and adjust treatments as needed. Individuals diagnosed with coronary artery disease and high LDL cholesterol levels may be suitable for this trial if they receive care at one of the specified clinics. As an unphased trial, this study offers participants the chance to contribute to innovative care approaches that could enhance heart disease treatment.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that pharmacist intervention in lipid therapy is safe?
Research has shown that pharmacist involvement in cholesterol management is both safe and effective. Studies have found that pharmacist-led programs can greatly improve cholesterol levels, reducing the risk of heart problems. A review of 26 studies involving over 22,000 patients demonstrated that pharmacists significantly reduced cholesterol levels. Additionally, the number of people adhering to cholesterol guidelines increased from 60% to over 92% with pharmacists' assistance. These results suggest that pharmacist involvement is well-received and enhances cholesterol management without safety concerns.12345
Why are researchers excited about this trial?
Researchers are excited about the pharmacist intervention for high cholesterol because it offers a personalized approach to managing lipid levels. Unlike standard treatments, which typically involve medications like statins, this method involves a pharmacist reviewing patient charts and conducting follow-up visits to tailor lipid therapy specifically to each individual's needs. This personalized care could potentially enhance the effectiveness of treatment by ensuring that patients receive the most appropriate therapy for their condition. By involving pharmacists directly in patient care, this intervention also adds an extra layer of professional oversight, which may improve adherence to treatment and overall outcomes.
What evidence suggests that pharmacist intervention is effective for high cholesterol?
This trial will compare a Pharmacist Intervention with a Control group. Studies have shown that pharmacists can help lower LDL cholesterol, often called "bad" cholesterol. One study demonstrated a significant drop in LDL levels, from 140 mg/dL to 70 mg/dL. Research also shows that pharmacists can help manage other heart disease risks. In this trial, the Pharmacist Intervention arm involves pharmacists reviewing patient charts and conducting follow-up visits to prescribe appropriate therapy for hyperlipidemia. These actions can lead to better heart health by ensuring patients receive the right treatment for high cholesterol.678910
Who Is on the Research Team?
Kayla Marvin, PharmD
Principal Investigator
Wake Forest University Health Sciences
Are You a Good Fit for This Trial?
This trial is for patients with coronary artery disease and high LDL cholesterol levels (>55), who are currently seeing a primary care physician at one of six specific clinics. It excludes women who could become pregnant, those managed by other practices, hospice or long-term care residents, and individuals with end-stage liver disease.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Pharmacist review of patient chart and follow-up visits to prescribe appropriate therapy for hyperlipidemia
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Pharmacist Intervention in lipid therapy
Trial Overview
The study aims to compare the effectiveness of pharmacist-led interventions in managing cholesterol using guideline-directed therapies versus usual care without this specialized intervention for secondary prevention in very high-risk patients.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Pharmacist review of patient chart and follow up visits to prescribe appropriate therapy for hyperlipidemia.
Chart review only
Find a Clinic Near You
Who Is Running the Clinical Trial?
Wake Forest University Health Sciences
Lead Sponsor
Citations
Effect of pharmacist interventions on reducing low-density ...
Pharmacist interventions significantly reduced LDL-C levels compared with usual care. Further research is warranted to determine the optimal pharmacist ...
Impact of the pharmacist‐led intervention on the control ...
The findings of this review suggest that pharmacist‐led interventions in general practice can significantly reduce the medical risk factors of cardiovascular ...
Pharmacist-Initiated Team-Based Intervention for Optimizing
Feasibility of an effective pharmacist-initiated intervention for improvement of lipid management was demonstrated by entry of recommendations ...
Pharmacist-Led Intervention Slashes LDL and BP in 10000 ...
For the 2,753 patients in maintenance, LDL cholesterol declined from 140 mg/dL to 70 mg/dL (P < 0.001). In the maintenance arm, these reductions ...
Optimization of Lipid-Lowering Therapy for High ...
The pharmacist recommended to intensify statin therapy for 16 patients (47.1%), initiate nonstatin therapy for 9 patients (26.5%), and initiate ...
Pharmacist optimization of lipid therapy in patients with ...
Lipid optimization studies in the primary care setting have shown that pharmacist-based interventions can increase statin prescribing and the ...
Learnings from Implementation Strategies to Improve Lipid ...
A systematic review and meta-analysis of 26 randomised trials (22,095 patients) found that pharmacist-led interventions significantly reduced ...
8.
pharmacytimes.com
pharmacytimes.com/view/pharmacist-led-clinic-optimizes-lipid-therapy-for-postacute-coronary-syndromesPharmacist-Led Clinic Optimizes Lipid Therapy for ...
Pharmacist-led interventions can significantly improve cholesterol levels, reducing the risk of further cardiovascular events. A case study ...
Value of the clinical pharmacist interventions in the application ...
Adherence with guideline recommendations was significantly improved from 60.3% to 92.6% (X2 = 79.1, p = 0.0001) after clinical pharmacist interventions. Among ...
10.
bmccardiovascdisord.biomedcentral.com
bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-02178-0Effects of a pharmaceutical care intervention on clinical ...
This was a prospective, randomized, controlled, outcomes-blinded trial designed to compare pharmaceutical care follow-up with standard care.
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