Aptensio Xr

Attention Deficit Hyperactivity Disorder

Treatment

1 FDA approval

20 Active Studies for Aptensio Xr

Treatment for

Attention Deficit Hyperactivity Disorder

What is Aptensio Xr

DexmethylphenidateThe Generic name of this drug

Treatment SummaryDexmethylphenidate is a medication used to treat Attention Deficit Hyperactivity Disorder (ADHD). It was released in 2002 and works by increasing the levels of two neurotransmitters, norepinephrine and dopamine, in the brain. Dexmethylphenidate has fewer side effects than other forms of methylphenidate and has been found to be more effective at treating symptoms of ADHD.

Ritalinis the brand name

Aptensio Xr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ritalin

Dexmethylphenidate

1955

400

Approved as Treatment by the FDA

Dexmethylphenidate, otherwise known as Ritalin, is approved by the FDA for 1 uses including Attention Deficit Hyperactivity Disorder .

Attention Deficit Hyperactivity Disorder

Helps manage Attention Deficit Hyperactivity Disorder (ADHD)

Effectiveness

How Aptensio Xr Affects PatientsDexmethylphenidate is an active form of the drug methylphenidate. It works by blocking the reuptake of two chemicals (norepinephrine and dopamine) in the brain.

How Aptensio Xr works in the bodyMethylphenidate blocks the action of dopamine and norepinephrine in the brain, particularly in the thalamus and striatum. Studies in animals have shown that it affects blood flow in the prefrontal cortex, supplementary motor area, and posterior parietal cortex.

When to interrupt dosage

The measure of Aptensio Xr is based on the diagnosed affliction. The amount of dosage fluctuates in relation to the mode of administration (e.g. Tablet, film coated, extended release or Capsule, extended release) recorded in the table below.

Condition

Dosage

Administration

Attention Deficit Hyperactivity Disorder

, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 15.0 mg, 25.0 mg, 35.0 mg, 2.5 mg, 10.0 mg/mL, 5.0 mg/mL, 18.0 mg, 36.0 mg, 27.0 mg, 54.0 mg, 72.0 mg, 85.0 mg, 55.0 mg, 45.0 mg, 70.0 mg, 80.0 mg, 60.0 mg, 100.0 mg, 50.0 mg, 10.4 mg, 6.0 mg/mL, 5.2 mg, 9.0 mg/mL, 30.0 mg/mL, 7.5 mg/mL, 7.8 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Solution - Oral, Solution, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Tablet, Chewable, Extended Release, Suspension, extended release, Tablet, Chewable, Extended Release - Oral, Suspension, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral

Warnings

Aptensio Xr has nine counterindications, so it should be avoided for the situations mentioned in the following table.Aptensio Xr Contraindications

Condition

Risk Level

Notes

Gilles de la Tourette syndrome

Do Not Combine

Tension-Type Headache

Do Not Combine

Agitation

Do Not Combine

Pulse Frequency

Do Not Combine

Tourette Syndrome

Do Not Combine

Tics

Do Not Combine

Generalized Anxiety Disorder

Do Not Combine

Open-angle glaucoma

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Dexmethylphenidate may interact with Pulse Frequency

There are 20 known major drug interactions with Aptensio Xr.

Common Aptensio Xr Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Desflurane

Major

Dexmethylphenidate may increase the hypertensive activities of Desflurane.

Diethyl ether

Major

Dexmethylphenidate may increase the hypertensive activities of Diethyl ether.

Enflurane

Major

Dexmethylphenidate may increase the hypertensive activities of Enflurane.

Ethanol

Major

Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Aptensio Xr Toxicity & Overdose RiskThe effects of dexmethylphenidate are the same for men and women. Not much research has been done on its effects on people under 6 years old, those with kidney or liver disease, pregnant women, or those who are breastfeeding. Those with kidney problems do not need to adjust their dose, as the drug is not mainly cleared from the kidneys. Animal studies have shown delayed bone growth in unborn babies and reduced weight gain in male offspring. It is important to weigh the benefits and risks of taking this drug. The maximum recommended human dose in mice caused hepatoblastomas (liver tumors), and it can be weakly clastogenic

image of a doctor in a lab doing drug, clinical research

Aptensio Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Aptensio Xr?

Research is ongoing to determine the efficacy of Aptensio XR in the management of Attention Deficit Hyperactivity Disorder, with 77 active studies currently being conducted.

Condition

Clinical Trials

Trial Phases

Attention Deficit Hyperactivity Disorder

65 Actively Recruiting

Not Applicable, Phase 3, Phase 4, Phase 2, Phase 1, Early Phase 1

Aptensio Xr Reviews: What are patients saying about Aptensio Xr?

3.3Patient Review

5/15/2016

Aptensio Xr for Attention Deficit Disorder with Hyperactivity

2.7Patient Review

10/25/2016

Aptensio Xr for Attention Deficit Disorder with Hyperactivity

We're still testing dosages to see what will work for my daughter, but so far this has been fairly effective.

Patient Q&A Section about aptensio xr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Aptensio XR a controlled substance?

"Aptensio XR contains methylphenidate, a Schedule II controlled substance."

Answered by AI

Is Aptensio the same as Ritalin?

"Aptensio XR is a once-daily methylphenidate medication with the same active ingredient as Ritalin and Daytrana. It is available in capsule form in 10, 15, 20, 30, 40, 50, and 60 mg doses."

Answered by AI

What is Aptensio XR used for?

"This medication is used to treat attention deficit hyperactivity disorder (ADHD). It works by changing the amounts of certain natural substances in the brain. Methylphenidate belongs to a class of drugs known as stimulants."

Answered by AI

Is Aptensio XR like Adderall?

"Aptensio XR takes longer to start working than other forms of instant release medication, such as Ritalin, but it lasts up to 12 hours. Other medications, such as Adderall, are also available in extended release versions which last for the same amount of time."

Answered by AI

Clinical Trials for Aptensio Xr

Have you considered Aptensio Xr clinical trials? We made a collection of clinical trials featuring Aptensio Xr, we think they might fit your search criteria.

Have you considered Aptensio Xr clinical trials? We made a collection of clinical trials featuring Aptensio Xr, we think they might fit your search criteria.