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What is Aptensio Xr
DexmethylphenidateThe Generic name of this drug
Treatment SummaryDexmethylphenidate is a medication used to treat Attention Deficit Hyperactivity Disorder (ADHD). It was released in 2002 and works by increasing the levels of two neurotransmitters, norepinephrine and dopamine, in the brain. Dexmethylphenidate has fewer side effects than other forms of methylphenidate and has been found to be more effective at treating symptoms of ADHD.
Ritalinis the brand name
Aptensio Xr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ritalin
Dexmethylphenidate
1955
400
Approved as Treatment by the FDA
Dexmethylphenidate, otherwise known as Ritalin, is approved by the FDA for 1 uses including Attention Deficit Hyperactivity Disorder .Attention Deficit Hyperactivity Disorder
Helps manage Attention Deficit Hyperactivity Disorder (ADHD)
Effectiveness
How Aptensio Xr Affects PatientsDexmethylphenidate is an active form of the drug methylphenidate. It works by blocking the reuptake of two chemicals (norepinephrine and dopamine) in the brain.
How Aptensio Xr works in the bodyMethylphenidate blocks the action of dopamine and norepinephrine in the brain, particularly in the thalamus and striatum. Studies in animals have shown that it affects blood flow in the prefrontal cortex, supplementary motor area, and posterior parietal cortex.
When to interrupt dosage
The measure of Aptensio Xr is based on the diagnosed affliction. The amount of dosage fluctuates in relation to the mode of administration (e.g. Tablet, film coated, extended release or Capsule, extended release) recorded in the table below.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 15.0 mg, 25.0 mg, 35.0 mg, 2.5 mg, 10.0 mg/mL, 5.0 mg/mL, 18.0 mg, 36.0 mg, 27.0 mg, 54.0 mg, 72.0 mg, 85.0 mg, 55.0 mg, 45.0 mg, 70.0 mg, 80.0 mg, 60.0 mg, 100.0 mg, 50.0 mg, 10.4 mg, 6.0 mg/mL, 5.2 mg, 9.0 mg/mL, 30.0 mg/mL, 7.5 mg/mL, 7.8 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Solution - Oral, Solution, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Tablet, Chewable, Extended Release, Suspension, extended release, Tablet, Chewable, Extended Release - Oral, Suspension, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
Aptensio Xr has nine counterindications, so it should be avoided for the situations mentioned in the following table.Aptensio Xr ContraindicationsCondition
Risk Level
Notes
Gilles de la Tourette syndrome
Do Not Combine
Tension
Do Not Combine
Agitation
Do Not Combine
Pulse Frequency
Do Not Combine
diagnosed tourette's syndrome
Do Not Combine
Tic, Motor
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
Open-angle glaucoma
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dexmethylphenidate may interact with Pulse Frequency
Common Aptensio Xr Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Desflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Dexmethylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Enflurane.
Ethanol
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Aptensio Xr Toxicity & Overdose RiskThe effects of dexmethylphenidate are the same for men and women. Not much research has been done on its effects on people under 6 years old, those with kidney or liver disease, pregnant women, or those who are breastfeeding. Those with kidney problems do not need to adjust their dose, as the drug is not mainly cleared from the kidneys. Animal studies have shown delayed bone growth in unborn babies and reduced weight gain in male offspring. It is important to weigh the benefits and risks of taking this drug. The maximum recommended human dose in mice caused hepatoblastomas (liver tumors), and it can be weakly clastogenic
Aptensio Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Aptensio Xr?
Research is ongoing to determine the efficacy of Aptensio XR in the management of Attention Deficit Hyperactivity Disorder, with 77 active studies currently being conducted.Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
70 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Aptensio Xr Reviews: What are patients saying about Aptensio Xr?
3.3Patient Review
5/15/20162.7Patient Review
10/25/2016 We're still testing dosages to see what will work for my daughter, but so far this has been fairly effective.
Patient Q&A Section about aptensio xr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Aptensio XR a controlled substance?
"Aptensio XR contains methylphenidate, a Schedule II controlled substance."
Answered by AI
Is Aptensio the same as Ritalin?
"Aptensio XR is a once-daily methylphenidate medication with the same active ingredient as Ritalin and Daytrana. It is available in capsule form in 10, 15, 20, 30, 40, 50, and 60 mg doses."
Answered by AI
What is Aptensio XR used for?
"This medication is used to treat attention deficit hyperactivity disorder (ADHD). It works by changing the amounts of certain natural substances in the brain. Methylphenidate belongs to a class of drugs known as stimulants."
Answered by AI
Is Aptensio XR like Adderall?
"Aptensio XR takes longer to start working than other forms of instant release medication, such as Ritalin, but it lasts up to 12 hours. Other medications, such as Adderall, are also available in extended release versions which last for the same amount of time."
Answered by AI