Viibryd

Depression
Treatment
1 FDA approval
20 Active Studies for Viibryd

What is Viibryd

VilazodoneThe Generic name of this drug
Treatment SummaryVilazodone is a drug used to treat depression and anxiety. It works by targeting serotonin, a chemical in the brain that affects mood. Vilazodone is known to have fewer side effects related to sexual dysfunction and weight gain, and was approved by the FDA in 2011.
Viibrydis the brand name
image of different drug pills on a surface
Viibryd Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Viibryd
Vilazodone
2011
41

Approved as Treatment by the FDA

Vilazodone, also known as Viibryd, is approved by the FDA for 1 uses such as Depression .
Depression

Effectiveness

How Viibryd Affects PatientsVilazodone helps increase the amount of serotonin in the brain. It does this by blocking serotonin from being reabsorbed and by stimulating the serotonin-1A receptors. Because of its combination of effects, vilazodone is sometimes called a selective partial agonist and reuptake inhibitor (SPARI).
How Viibryd works in the bodyVilazodone helps treat depression by blocking serotonin from leaving your brain. It also helps activate serotonin receptors, which can further help reduce depressive symptoms. It's not clear exactly how this works to treat depression, but there is evidence that it does.

When to interrupt dosage

The advised dosage of Viibryd is contingent upon the identified condition. The measure of dosage is dependent on the approach of delivery (e.g. Tablet - Oral or Tablet, film coated - Oral) outlined in the chart beneath.
Condition
Dosage
Administration
Depression
, 40.0 mg, 10.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Kit; Tablet - Oral, Kit; Tablet, Kit, Kit - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

Viibryd Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Viibryd.
Common Viibryd Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methylene blue
Major
Vilazodone may increase the serotonergic activities of Methylene blue.
Mirtazapine
Major
Vilazodone may increase the serotonergic activities of Mirtazapine.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Vilazodone is combined with Oliceridine.
Viibryd Toxicity & Overdose RiskThere is not enough information to know if vilazodone is safe for pregnant or nursing mothers to take. Animal studies have shown that it can cause reduced fetal weight, increased mortality, delayed maturation, and decreased fertility in offspring. Babies born to mothers who take vilazodone may have difficulty breathing, seizures, and trouble controlling their temperature. Vilazodone has not been tested in children, but other antidepressants have been linked to an increased risk of suicidal thoughts and behaviors in those under 24 years of age. Elderly people may need a lower dose. Dosage adjustments are not necessary for patients of different genders or with reduced
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Viibryd Novel Uses: Which Conditions Have a Clinical Trial Featuring Viibryd?

186 active clinical trials are presently probing the potential of Viibryd in alleviating Depression.
Condition
Clinical Trials
Trial Phases
Depression
208 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1, Early Phase 1

Viibryd Reviews: What are patients saying about Viibryd?

4.3Patient Review
5/18/2022
Viibryd for Major Depressive Disorder
As a 57 year old disabled veteran with SMI, PTSD, anxiety and depression, this medication has truly changed my life for the better. Thank you.
3Patient Review
9/15/2022
Viibryd for Major Depressive Disorder
I've been struggling with depression for a while now. I was diagnosed with major depressive disorder a few years ago and have tried different medications since then. Viibryd is the newest one I've started taking, but unfortunately it's not working well for me. I'm already experiencing suicidal ideation and crying more than usual. Hopefully my doctor can help me next week.
2.7Patient Review
4/5/2022
Viibryd for Major Depressive Disorder
Unfortunately, this medication led to GI bleeding for me. Additionally, it caused my blood pressure to rise and I experienced insomnia, sleep paralysis, and nightmares.
2.7Patient Review
5/8/2022
Viibryd for Major Depressive Disorder
I've been on this for four days now, and the diarrhea has yet to let up. I also haven't had an appetite since starting the medication. On the plus side, though, my anxiety has decreased and headaches have all but disappeared.
2Patient Review
8/3/2022
Viibryd for Major Depressive Disorder
I had a really bad experience with this drug. I was on it for two weeks and ended up in the ER as a result of constant crying, rage, and more.
View All Reviews
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Patient Q&A Section about viibryd

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the most common side effects of Viibryd?

"The following are all possible side effects of the medication: nausea and vomiting, diarrhea, dry mouth, indigestion, belly pain, headache, dizziness, and trouble sleeping."

Answered by AI

Is Viibryd good for anxiety?

"The drug vilazodone, which is approved for the treatment of major depressive disorder, is also effective in relieving anxiety symptoms in patients with generalized anxiety disorder."

Answered by AI

What are the benefits of Viibryd?

"It helps to restore the balance of neurotransmitters in the brain, such as serotonin, which can improve mood, sleep, appetite, energy, and interest in daily activities."

Answered by AI

How does Viibryd make you feel?

"The drug Viibryd may work for some people based on other reviews, but I personally experienced negative side effects that got worse over time. These side effects included nausea, indigestion, and overall feeling sick."

Answered by AI

Clinical Trials for Viibryd

Image of Duke University School of Medicine in Durham, United States.

Combining rTMS & Aerobic Exercise for Stroke

21 - 70
All Sexes
Durham, NC
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD). Investigators propose to determine the efficacy of combining two known anti-depressant treatments shown to be effective in non-stroke depression, aerobic exercise (AEx) and repetitive transcranial magnetic stimulation (rTMS), on post-stroke depressive symptoms. This project is based on the idea that depression negatively affects the potential for the brain to adapt in response to treatment such that rehabilitation may not produce the same changes that it does in non-depressed individuals. Investigators believe that effective treatment for PSD will result in a virtuous cycle whereby reducing depression enhances response to rehabilitation, thereby facilitating functional gains. That is, effectively treating depression will enable individuals to better recover from stroke.
Recruiting
Has No Placebo
Duke University School of Medicine (+1 Sites)
Have you considered Viibryd clinical trials? We made a collection of clinical trials featuring Viibryd, we think they might fit your search criteria.Go to Trials
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Pramipexole for Depression

18 - 65
All Sexes
Stanford, CA
This research study aims to understand how people with depression respond to the medication pramipexole and to determine whether clinical response differs depending on the function of specific circuits in the brain. The investigators hope to learn which circuits are involved in depression and how these circuits interact with pramipexole to affect mood, behavior, and cognition. Eligible participants will undergo an 8-week treatment course of pramipexole followed by a 2-week down taper and follow up. The ultimate goal is to offer people experiencing depression a medication that is alternative to ones that may not have worked in the past and to apply the knowledge the investigators gain from investigating the brain circuits involved in depression to help personalize treatment. The investigators invite anyone who has recently experienced symptoms of depression to participate. A prior diagnosis of depression is not required.
Phase 2
Waitlist Available
Stanford University
Have you considered Viibryd clinical trials? We made a collection of clinical trials featuring Viibryd, we think they might fit your search criteria.Go to Trials
Have you considered Viibryd clinical trials? We made a collection of clinical trials featuring Viibryd, we think they might fit your search criteria.Go to Trials
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