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What is Tyzeka
TelbivudineThe Generic name of this drug
Treatment SummaryTelbivudine is a medication used to treat hepatitis B virus infections. It is taken by mouth and has few side effects and no dose-limiting issues. It is well tolerated and has no toxicity.
Tyzekais the brand name
Tyzeka Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tyzeka
Telbivudine
2006
3
Approved as Treatment by the FDA
Telbivudine, also known as Tyzeka, is approved by the FDA for 1 uses including Chronic Hepatitis B Infection .Chronic Hepatitis B Infection
Helps manage Hepatitis B Chronic Infection
Effectiveness
How Tyzeka Affects PatientsTelbivudine is a type of medicine used to treat hepatitis B. It is made from the same building blocks as a natural substance called thymidine. When telbivudine is taken, it is changed in the body by certain enzymes into an active form that works against the virus.
How Tyzeka works in the bodyTelbivudine stops the hepatitis B virus from replicating. It does this by competing with another molecule, thymidine 5'–triphosphate, that the virus needs to make copies of itself. By taking the place of this molecule, telbivudine stops the virus from making new copies of itself, which stops it from spreading further.
When to interrupt dosage
The appropriate dosage of Tyzeka is contingent upon the diagnosed affliction. The amount of dosage also varies as per the administration technique (e.g. Tablet, film coated - Oral or Oral) recorded in the table below.Condition
Dosage
Administration
Chronic Hepatitis B Infection
, 20.0 mg/mL, 600.0 mg
, Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
Tyzeka has two counter-indications. Under no circumstances should it be taken in combination with the conditions listed in the table below.Tyzeka ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Telbivudine may interact with Pulse Frequency
Common Tyzeka Drug Interactions
Drug Name
Risk Level
Description
Adenovirus type 7 vaccine live
Moderate
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Telbivudine.
Anthrax vaccine
Moderate
The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Telbivudine.
BCG vaccine
Moderate
The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Telbivudine.
Bacillus calmette-guerin substrain connaught live antigen
Moderate
The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Telbivudine.
Bacillus calmette-guerin substrain russian BCG-I live antigen
Moderate
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Telbivudine.
Tyzeka Toxicity & Overdose RiskThere are no reports of intentional overdose on telbivudine, but one person experienced an unintentional and symptomless overdose. Healthy people who took up to 1800 mg of telbivudine per day for 4 days didn't have any extra or unexpected side effects. We don't know what the highest tolerated dose of telbivudine is.
Tyzeka Novel Uses: Which Conditions Have a Clinical Trial Featuring Tyzeka?
Three active clinical trials are assessing the potential of Tyzeka to alleviate Chronic Hepatitis B.Condition
Clinical Trials
Trial Phases
Chronic Hepatitis B Infection
7 Actively Recruiting
Phase 3, Phase 2, Phase 1
Patient Q&A Section about tyzeka
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long can hepatitis B be treated?
"Hepatitis b infection may be acute (short-lived) or chronic (long-lasting). Acute hepatitis B infection lasts less than six months and usually goes away on its own."
Answered by AI
Why was telbivudine discontinued?
"Telbivudine was approved by the United States in 2006 to be used as a therapy for chronic hepatitis b, either by itself or with other agents. It was withdrawn from the United States market in 2016 for mostly economic reasons. Telbivudine was previously accessible as 600 mg tablets under the brand name Tyzeka."
Answered by AI
What kind of drug is telbivudine?
"Telbivudine is used to treat chronic hepatitis b infection by reducing the amount of hepatitis B virus in the body. It is part of a class of medications called nucleoside analogues."
Answered by AI
What is tyzeka used for?
"Tyzeka is a medication used to treat an active, chronic hepatitis b infection. It is a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by inserting themselves into the virus' DNA (genetic material)."
Answered by AI