Transcranial Magnetic Stimulation for Chronic Subcortical White Matter Disease

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Chronic Subcortical White Matter DiseaseTranscranial Magnetic Stimulation - Device
Eligibility
3 - 21
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether a wearable device that sends magnetic pulses to the brain can help treat epilepsy.

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: After one single 10 minute stimulation

After one single 10 minute stimulation
Change in Spike-Wave Index (SWI) on EEG during sleep following one time 10 minutes of TRPMS-ECA (epileptogenic cortical area) stimulation
Duration of sustainability (hours) of change in SWI achieved post stimulation

Trial Safety

Trial Design

1 Treatment Group

Treatment Group
1 of 1

Experimental Treatment

10 Total Participants · 1 Treatment Group

Primary Treatment: Transcranial Magnetic Stimulation · No Placebo Group · N/A

Treatment Group
Device
Experimental Group · 1 Intervention: Transcranial Magnetic Stimulation · Intervention Types: Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
2011
Completed Phase 4
~580

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: after one single 10 minute stimulation

Who is running the clinical trial?

Cornell UniversityOTHER
149 Previous Clinical Trials
100,840 Total Patients Enrolled
The Methodist Hospital Research InstituteOTHER
239 Previous Clinical Trials
35,578 Total Patients Enrolled
Children's Mercy Hospital Kansas CityLead Sponsor
226 Previous Clinical Trials
1,269,608 Total Patients Enrolled
Lalit Bansal, M.D.Principal InvestigatorChildren's Mercy Hospital Kansas City

Eligibility Criteria

Age 3 - 21 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a minimum age of 3 years old.
You have focal CSWS as defined by ILAE.
You have a SWI of at least 85% in sleep on EEG's performed on previous or most recent EEG study.
No change in AED in last 2 weeks, or patients not on any AED.
References