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Behavioral Intervention

High-Intensity Exercise for Cognitive Impairment with HIV

N/A

Waitlist Available

Led By Raymond Jones, Ph.D.

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, up to 12 weeks, 3-months post-intervention

Awards & highlights

Study Summary

This trial will study if exercise can help people 50+ living with HIV who have suboptimal cognition. 60 participants in Alabama will be monitored over 3 months to measure the effects of exercise.

Who is the study for?

This trial is for adults over 50 living with HIV who have cognitive challenges and a sedentary lifestyle. They must be on HIV treatment without old drugs known to harm mitochondria, speak English, and not engage in moderate exercise more than 150 minutes per week. Exclusions include severe heart disease, uncontrolled diabetes or hypertension, kidney or mitochondrial diseases, active substance abuse, orthopedic limitations to exercise, other trials' participation, or needing oxygen for lung issues.Check my eligibility

What is being tested?

The study compares two types of exercises: high-intensity interval training (HIIT) versus continuous moderate exercise to see which better improves blood vessel health and brain function in older adults with HIV after 12 weeks. It also explores participants' barriers to exercising and their views on the interventions.See study design

What are the potential side effects?

While specific side effects are not listed for these exercises, general risks may include muscle soreness, fatigue during or after workouts, joint pain due to physical activity intensity increase especially if previously sedentary.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, up to 12 weeks, 3-months post-intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, up to 12 weeks, 3-months post-intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, up to 12 weeks, 3-months post-intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in cognitive function

Change in vascular function

Secondary outcome measures

Barriers to Engagement in Exercise

Perceptions of the Study and Exercise Interventions

Other outcome measures

Participant Safety, Adherence to the Intervention, Retention

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: High-Intensity Interval TrainingExperimental Treatment1 Intervention

Group II: Continuous Moderate ExerciseActive Control1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

High-Intensity Interval Training

2019

N/A

~570

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,584 Previous Clinical Trials

2,280,013 Total Patients Enrolled

Raymond Jones, Ph.D.Principal InvestigatorUniversity of Alabama at Birmingham

Media Library

Continuous Moderate Exercise (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05965518 — N/A

Arterial Stiffness Research Study Groups: High-Intensity Interval Training, Continuous Moderate Exercise

Arterial Stiffness Clinical Trial 2023: Continuous Moderate Exercise Highlights & Side Effects. Trial Name: NCT05965518 — N/A

Continuous Moderate Exercise (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05965518 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this exploration actively calling for new participants?

"According to the details posted on clinicaltrials.gov, this specific medical investigation is not admitting patients presently. The protocol for enrollment was first published in September of 2023 and last revised at the end of July that year; however, there are still 836 other studies recruiting participants right now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

Raymond Jones 2024. "High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05965518.

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