Study Summary
This trial is testing two different combinations of drugs to see which is more effective and has fewer side effects in treating locally advanced pancreatic cancer.
Eligible Conditions
- Pancreatic Cancer
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: Time from first dose until subject has reached 90 days post last active study treatment
Day 90
Progression free survival
Day 90
Incidence of Adverse and Serious Adverse events will be captured (safety and tolerability)
Trial Safety
Safety Progress
Trial Design
0 Treatment Group
20 Total Participants · 0 Treatment Group
Primary Treatment: Treatment · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: time from first dose until subject has reached 90 days post last active study treatment
Who is running the clinical trial?
University of LouisvilleLead Sponsor
314 Previous Clinical Trials
72,920 Total Patients Enrolled
Robert Martin, MD, PhDPrincipal InvestigatorUniversity of Louisville
5 Previous Clinical Trials
18,058 Total Patients Enrolled
Eligibility Criteria
Age 18+ · All Participants · 7 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:You are eligible for the study if you are at least 18 years of age.
You have a tumor that is measurable.
References
- Bhutiani, Neal, Yan Li, Qianqian Zheng, Harshul Pandit, Xiaoju Shi, Yujia Chen, Youxi Yu, Zachary R. Pulliam, Min Tan, and Robert C. G. Martin II. 2020. “Electrochemotherapy with Irreversible Electroporation and FOLFIRINOX Improves Survival in Murine Models of Pancreatic Adenocarcinoma”. Annals of Surgical Oncology. Springer Science and Business Media LLC. doi:10.1245/s10434-020-08782-2.
- Robert C. Martin 2018. "Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03484299.
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Conditions
Cancer Related
Treatments