Soltamox

Sexual Precocity, Gynecomastia, Ovulation induction therapy + 12 more
Treatment
12 FDA approvals
20 Active Studies for Soltamox

What is Soltamox

TamoxifenThe Generic name of this drug
Treatment SummaryTamoxifen is a type of medication used to treat certain types of breast cancer and to prevent the development of breast cancer in high risk individuals. It is usually given alone or in combination with other treatments. Tamoxifen has generally been replaced by another drug called anastrozole, which has been found to have better survival rates, fewer side effects, and better patient compliance. Tamoxifen was approved by the FDA in 1977.
Nolvadexis the brand name
image of different drug pills on a surface
Soltamox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nolvadex
Tamoxifen
1990
60

Approved as Treatment by the FDA

Tamoxifen, also called Nolvadex, is approved by the FDA for 12 uses which include Estrogen Receptors and Breast Cancer .
Estrogen Receptors
Breast Cancer
Invasive Breast Cancer
Ductal Carcinoma In Situ
Malignant Neoplasms
Malignant Neoplasms
Breast Cancer
Breast
Breast Surgery
Carcinoma, Intraductal, Noninfiltrating
Breast Cancer Radiation
High Risk

Effectiveness

How Soltamox Affects PatientsTamoxifen is a drug that can help stop the growth and spread of certain types of cancer. Its effects last for about two weeks, so it needs to be taken regularly for it to be effective. Taking too much of it can lead to breathing difficulties or seizures, so it is important to take the correct dose. It can also increase the risk of developing cancer of the uterus.
How Soltamox works in the bodyTamoxifen blocks the effects of estrogen on cells, which helps stop the growth of tumors. It does this by decreasing tumor growth factors, increasing a hormone that binds to estrogen, and causing apoptosis (cell death) in estrogen-sensitive cells. This cell death is thought to be caused by an increase in calcium ion levels or the introduction of a tumor growth factor.

When to interrupt dosage

The suggested dose of Soltamox relies upon the diagnosed condition, including Ovulation induction therapy, Malignant Neoplasms and McCune Albright Syndrome. The amount of dosage is contingent upon the method of delivery featured in the table below.
Condition
Dosage
Administration
Ovulation induction therapy
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Breast Surgery
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
High Risk
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Fibromatosis, Aggressive
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Estrogen Receptors
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Breast Cancer Radiation
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Breast
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Sexual Precocity
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Breast Cancer
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Carcinoma, Intraductal, Noninfiltrating
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Gynecomastia
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Ovarian Cancer
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Fibrous Dysplasia, Polyostotic
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Malignant Neoplasms
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit
Malignant Neoplasms
, 10.0 mg, 10.0 mg/mL, 20.0 mg, 2.0 mg/mL, 1.0 mg/mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Kit

Warnings

Soltamox has four contraindications, so its usage should be avoided when going through any of the conditions shown in the subsequent table.Soltamox Contraindications
Condition
Risk Level
Notes
Venous Thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
Pulmonary Embolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Tamoxifen may interact with Pulse Frequency
There are 20 known major drug interactions with Soltamox.
Common Soltamox Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Tamoxifen.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Tamoxifen.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Tamoxifen.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Tamoxifen.
Anastrozole
Major
The serum concentration of Anastrozole can be decreased when it is combined with Tamoxifen.
Soltamox Toxicity & Overdose RiskTaking too much tamoxifen can cause difficulty breathing and seizures in animals, and dizziness, tremors, and difficulty with coordination in humans. If someone overdoses on tamoxifen, supportive care should be provided as there is no specific treatment for an overdose.
image of a doctor in a lab doing drug, clinical research

Soltamox Novel Uses: Which Conditions Have a Clinical Trial Featuring Soltamox?

Presently, there are 930 active trials examining the potential of Soltamox to mitigate Breast Cancer Radiation, Gynecomastia and Malignant Neoplasms.
Condition
Clinical Trials
Trial Phases
Breast Cancer Radiation
1 Actively Recruiting
Phase 2
Malignant Neoplasms
0 Actively Recruiting
Fibrous Dysplasia, Polyostotic
0 Actively Recruiting
Breast Cancer
26 Actively Recruiting
Phase 2, Phase 1, Not Applicable
Ovulation induction therapy
0 Actively Recruiting
Breast Surgery
0 Actively Recruiting
Estrogen Receptors
0 Actively Recruiting
Malignant Neoplasms
4 Actively Recruiting
Phase 2, Not Applicable
Breast
0 Actively Recruiting
Carcinoma, Intraductal, Noninfiltrating
0 Actively Recruiting
Sexual Precocity
0 Actively Recruiting
Gynecomastia
0 Actively Recruiting
Fibromatosis, Aggressive
2 Actively Recruiting
Phase 2, Phase 3
Ovarian Cancer
17 Actively Recruiting
Phase 1, Phase 2, Not Applicable
High Risk
1 Actively Recruiting
Phase 1

Soltamox Reviews: What are patients saying about Soltamox?

5Patient Review
2/14/2013
Soltamox for Breast Cancer
4.7Patient Review
9/15/2012
Soltamox for Breast Cancer

Patient Q&A Section about soltamox

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is SOLTAMOX used for?

"SOLTAMOX can be used to treat adults with estrogen receptor-positive breast cancer that has spread to other parts of the body or early stage breast cancer after surgery and radiation."

Answered by AI

Who makes SOLTAMOX?

"Savient's wholly-owned subsidiary Rosemont Pharmaceuticals Ltd. located in Leeds, U.K. has created Soltamox. This is the first oral liquid product entry into the market from Savient's wholly-owned U.K. subsidiary. The product is an oral solution of tamoxifen, which will be available in the United States."

Answered by AI

How do you take SOLTAMOX?

"Doses of SOLTAMOX greater than 20 mg per day should be given in divided doses (morning and evening), as greater doses yield no additional clinical benefit in the adjuvant setting for breast cancer."

Answered by AI

How much does SOLTAMOX cost?

"The price of Soltamox is around $1,354.63, cheaper than the average retail price of $1,552.16 by 12%."

Answered by AI

Clinical Trials for Soltamox

Have you considered Soltamox clinical trials? We made a collection of clinical trials featuring Soltamox, we think they might fit your search criteria.
Have you considered Soltamox clinical trials? We made a collection of clinical trials featuring Soltamox, we think they might fit your search criteria.
Have you considered Soltamox clinical trials? We made a collection of clinical trials featuring Soltamox, we think they might fit your search criteria.
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