Re-irradiation for Breast Cancer
(BRASIL Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this research study is to test the safety and possible harms of treating breast cancer with reirradiation, after breast surgery. The researchers want to find out what effects (good and bad) reirradiation has on people who have already received radiation before surgery.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial team or your doctor.
Is re-irradiation for breast cancer using IMRT generally safe for humans?
IMRT is generally considered safe and is widely used for various conditions, including breast cancer. It allows for precise targeting of radiation, reducing exposure to healthy tissue, but requires careful planning and safety checks. Some studies show it reduces skin side effects compared to traditional methods.12345
How is intensity-modulated radiation therapy (IMRT) different from other treatments for breast cancer?
Intensity-modulated radiation therapy (IMRT) is unique because it allows for highly precise targeting of radiation doses, which can improve treatment effectiveness and reduce side effects compared to traditional radiation therapy. This precision is particularly beneficial in re-irradiation scenarios, where minimizing damage to surrounding healthy tissue is crucial.16789
What data supports the effectiveness of the treatment Intensity modulated radiation therapy (IMRT) for breast cancer?
Who Is on the Research Team?
Youssef Zeidan, M.D., Ph.D.
Principal Investigator
Lynn Cancer Institute at Baptist Health, Inc.
Are You a Good Fit for This Trial?
This trial is for individuals who have had breast cancer and are undergoing a second lumpectomy. It's specifically for those who've already received radiation therapy before surgery and are now considering reirradiation.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgery
Participants undergo breast surgery prior to reirradiation
Reirradiation Treatment
Participants receive reirradiation treatment to test safety and possible harms
Follow-up
Participants are monitored for adverse events and survival outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Intensity modulated radiation therapy (IMRT)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Baptist Health South Florida
Lead Sponsor
Boca Raton Regional Hospital Foundation
Collaborator