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What is Quetiapine Fumarate
QuetiapineThe Generic name of this drug
Treatment SummaryQuetiapine is an antipsychotic drug used to treat schizophrenia, major depression, and bipolar disorder. It was approved by the FDA in 1997 and is known for its effectiveness and low risk of side effects. Quetiapine is a good option for patients who are sensitive to other drugs, such as Clozapine or Olanzapine.
Seroquelis the brand name
Quetiapine Fumarate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Seroquel
Quetiapine
1997
700
Approved as Treatment by the FDA
Quetiapine, also known as Seroquel, is approved by the FDA for 2 uses which include Bipolar Disorder and Depression .Bipolar Disorder
Used in combination with other therapies
Depression
Effectiveness
How Quetiapine Fumarate Affects PatientsQuetiapine helps improve symptoms of schizophrenia, major depression, and bipolar disorder by acting on the serotonin and dopamine receptors in the brain. However, it is not recommended for children under 10 years of age due to increased risk of suicidal thinking or behavior. In elderly patients, this drug has been linked to increased death rate and should be avoided. It is important to monitor for any signs of suicidality if this drug is prescribed to a young patient.
How Quetiapine Fumarate works in the bodyThe exact way quetiapine works is not known, but scientists think it works by blocking certain receptors in the brain. This might help with schizophrenia symptoms by blocking dopamine and serotonin receptors, and depression symptoms by blocking norepinephrine receptors. It also has side effects like drowsiness, low blood pressure, and a decrease in muscle control, which may be caused by blocking other receptors in the body.
When to interrupt dosage
The recommended dosage of Quetiapine Fumarate is contingent upon the determined condition, such as Mental Depression, Bipolar Disorder and Acute Coryza. The amount likewise shifts as outlined by the procedure of delivery indicated in the table below.Condition
Dosage
Administration
Acute Coryza
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Parkinson's Disease
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Depression
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Behcet Syndrome
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Post Traumatic Stress Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Schizophrenia
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Schizophrenia
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Mental Depression
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Bipolar Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Generalized Anxiety Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Bipolar Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
There are 20 known major drug interactions with Quetiapine Fumarate.Common Quetiapine Fumarate Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Quetiapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Quetiapine is combined with Aclidinium.
Alfuzosin
Major
Quetiapine may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Quetiapine may increase the antipsychotic activities of Amisulpride.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Quetiapine is combined with Anagrelide.
Quetiapine Fumarate Toxicity & Overdose RiskThe lowest toxic dose of quetiapine in rats is 2000mg/kg. Signs and symptoms of an overdose may include excessive sleepiness, rapid heartbeat, and low blood pressure. Studies have found that an overdose of up to 30 grams does not usually result in death, although one case of 13.6 grams was fatal. Treatment for overdose includes maintaining an open airway, providing oxygen and ventilation, and stomach pumping with activated charcoal and a laxative. It is important to monitor the heart rate as taking certain drugs concomitantly with quetiapine can increase the QT interval.
Quetiapine Fumarate Novel Uses: Which Conditions Have a Clinical Trial Featuring Quetiapine Fumarate?
At present, 705 active trials are assessing the capability of Quetiapine Fumarate to treat Depression, Schizophrenia and Bipolar Disorder.Condition
Clinical Trials
Trial Phases
Behcet Syndrome
2 Actively Recruiting
Not Applicable
Post Traumatic Stress Disorder
253 Actively Recruiting
Phase 4, Phase 1, Not Applicable, Early Phase 1, Phase 2, Phase 3
Bipolar Disorder
1 Actively Recruiting
Phase 4
Bipolar Disorder
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Generalized Anxiety Disorder
32 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4
Parkinson's Disease
46 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1
Depression
198 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Mental Depression
3 Actively Recruiting
Not Applicable
Schizophrenia
175 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Quetiapine Fumarate Reviews: What are patients saying about Quetiapine Fumarate?
5Patient Review
9/11/2022 Since taking this medication, I have seen vast improvements in my depression, anger, anxiety and sleep patterns.
5Patient Review
2/21/2022 This drug has really helped mepositively change my life. I'm grateful to the people who make this medicine possible.
4.7Patient Review
5/18/20214Patient Review
7/8/2021 Quetiapine has been a lifesaver for me. It's helped stabilize my mood and keep my panic attacks under control. I never feel like a shell of a person when I'm on this medication, which is something I struggled with on other medications. I'm just overall much happier and can appreciate the little things again.
3.7Patient Review
5/28/2021 Overall, I really enjoyed this treatment!
3.3Patient Review
9/5/2022 I've unfortunately gained a lot of weight since starting this medication, which has only stabilized my mood slightly. It also makes it hard to think clearly and get consistent sleep. Overall, I would not recommend it.
3Patient Review
8/26/2022 One of the side effects I experienced while taking this medication was a loss of balance. It didn't go away after stopping the drug, either. Has anyone else had this problem?
3Patient Review
10/14/2021 I've been taking this pill for a few years now and I'm honestly quite dependent on it.
2.3Patient Review
2/8/2022 I experienced a lot of side effects from this medication, including muscle pain, weight gain, and kidney problems. I also felt very tired and dizzy from it. Additionally, I found it to be quite addictive.
1.7Patient Review
12/4/2021 After taking this medication, I had a full-blown suicide experience where I begged for a car to hit me. My wife had to save me. The same psychiatrist is now trying to give it to me again after 5 years of that incident.
1Patient Review
10/25/2021 The horrible side effects aren't worth any benefits. I felt angry, tired, and my skin was burning and stinging. The next day I felt like a zombie. If you're thinking about trying this drug, beware that it might give you an allergic reaction.
Patient Q&A Section about quetiapine fumarate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the side effects of quetiapine fumarate?
"Dizziness, feeling unsteady, or having trouble keeping your balance can be caused by pain in the joints, back, neck, or ears, weakness, dry mouth, vomiting, indigestion, or constipation."
Answered by AI
What is quetiapine fumarate used for?
"Quetiapine is a medication that can be used to treat bipolar disorder and schizophrenia, either on its own or in combination with other medications. It can also be used in conjunction with other antidepressants to treat major depressive disorder."
Answered by AI
Is quetiapine fumarate a sleeping pill?
"Seroquel is not a medication for sleep aids, but rather a mental health medication that is approved by the FDA to treat psychiatric conditions such as schizophrenia, bipolar disorder, and major depressive disorder."
Answered by AI
Is quetiapine fumarate the same as Xanax?
"Seroquel is an antipsychotic medication and Xanax is a benzodiazepine. Seroquel and Xanax are different medications that are used to treat psychiatric disorders. Seroquel is an antipsychotic medication used to treat schizophrenia, major depression, and bipolar disorder. Xanax is a benzodiazepine used to treat panic attacks and anxiety disorders."
Answered by AI