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Procedure

XPERIENCE Advanced Surgical Irrigation for Osteoarthritis (XPERIENCE Trial)

N/A

Recruiting

Led By Simon Garceau, MD

Research Sponsored by Ottawa Hospital Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks after surgery

Awards & highlights

XPERIENCE Trial Summary

This trial will compare the rate of infection after knee or hip surgery using two different methods of surgical irrigation: XPERIENCE™ Advanced Surgical Irrigation and dilute Betadine.

Who is the study for?

This trial is for adults over 18 with knee or hip arthritis, osteoarthritis, osteonecrosis, or post-traumatic arthritis who need a total knee or hip replacement or hip resurfacing. Participants must be able to follow the study plan and attend all follow-ups.Check my eligibility

What is being tested?

The trial compares XPERIENCE Advanced Surgical Irrigation against dilute Betadine in preventing joint infections after primary total knee arthroplasty (TKA), total hip arthroplasty (THA), or hip resurfacing (HR). It's randomized and controlled to ensure fair results.See study design

What are the potential side effects?

Possible side effects may include skin irritation, allergic reactions, thyroid dysfunction due to iodine absorption from Betadine, and other complications related to surgery such as infection risk.

XPERIENCE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks after surgery, 3 months after surgery, within 90 day of surgery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks after surgery, 3 months after surgery, within 90 day of surgery

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks after surgery, 3 months after surgery, within 90 day of surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Heart rate

Secondary outcome measures

Patient Reported Functional Outcome Scores

Patient Reported Quality of Life Scores

Rate of PJI at 1 year

+3 more

XPERIENCE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: XPERIENCE Advanced Surgical IrrigationExperimental Treatment1 Intervention

Patients will receive the XPERIENCE Advanced Surgical Irrigation prior to wound closure.

Group II: Dilute BetadineActive Control1 Intervention

Patients will receive Dilute Betadine solution prior to wound closure.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Ottawa Hospital Research InstituteLead Sponsor

563 Previous Clinical Trials

2,780,114 Total Patients Enrolled

26 Trials studying Osteoarthritis

182,406 Patients Enrolled for Osteoarthritis

Next Science TMIndustry Sponsor

15 Previous Clinical Trials

1,924 Total Patients Enrolled

Simon Garceau, MDPrincipal InvestigatorThe Ottawa Hospital

1 Previous Clinical Trials

80 Total Patients Enrolled

1 Trials studying Osteoarthritis

80 Patients Enrolled for Osteoarthritis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In how many medical institutions is this clinical examination currently being conducted?

"Nine patients are currently being enrolled at institutions like McGill University in Ottawa, The Ottawa Hospital in Vancouver, and the University of British Columbia in London, among nine additional sites."

Answered by AI

Are there any available slots for patients to participate in this clinical trial?

"Yes, information from clinicaltrials.gov confirms that recruitment for this research is ongoing. The trial was first listed on April 1st, 2023 and the latest update was made on April 2nd, 2024. Enrollment of approximately 7600 participants will take place across nine designated locations."

Answered by AI

What is the upper limit on the number of individuals enrolled in this clinical trial?

"To conduct the investigation, a total of 7600 eligible individuals meeting the trial's inclusion criteria are required. The sponsor, Next Science TM, will oversee operations at various sites such as McGill University in Ottawa, Ontario and The Ottawa Hospital in Vancouver, British Columbia."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluating XPERIENCE™ Advanced Surgical Irrigation

2023. "Evaluating XPERIENCE™ Advanced Surgical Irrigation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05543941.