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Dietary Oils for Obesity (DOSE Trial)

N/A
Waitlist Available
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Nonsmokers
BMI 25-55 kg/m2
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 0, week 2, week 4, week 6, week 8, week 10
Awards & highlights

DOSE Trial Summary

This trial will test if consuming 3 study foods per day, made with either soybean oil or palm oil, can change blood fatty acids and body weight in obese adults. The study will also assess if participants remain unaware of which food group they are consuming.

Who is the study for?
This trial is for overweight or obese adults aged 25-80 who don't smoke and have a BMI between 25-55. It's not suitable for those with heart, kidney, some liver diseases, cancer, diabetes, thyroid disorders, on certain medications including weight loss ones, pregnant or lactating women, substance abusers, people with food allergies/intolerances or specific dietary restrictions.Check my eligibility
What is being tested?
The study tests if eating foods made with soybean oil versus palm oil affects body fat composition and weight in overweight individuals. Participants will eat three of these foods daily for four weeks without knowing which oil they're consuming to see if there's a difference.See study design
What are the potential side effects?
While the study primarily focuses on diet changes rather than medication side effects are not detailed; however potential risks may include digestive discomfort due to new dietary oils.

DOSE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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You do not smoke cigarettes.
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Your body mass index (BMI) is between 25 and 55.

DOSE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 0, week 2, week 4, week 6, week 8, week 10
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 0, week 2, week 4, week 6, week 8, week 10 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in blood fatty acid composition
Secondary outcome measures
Adherence to study food consumption
Changes in body weight
Evidence of unmasking

DOSE Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Soybean OilExperimental Treatment1 Intervention
Consumption of study foods each day made with soybean oil
Group II: Palm OilPlacebo Group1 Intervention
Consumption of study foods each day made with palm oil

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor
821 Previous Clinical Trials
501,119 Total Patients Enrolled
24 Trials studying Obesity
4,041 Patients Enrolled for Obesity

Media Library

Palm Oil Foods (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04975763 — N/A
Obesity Research Study Groups: Soybean Oil, Palm Oil
Obesity Clinical Trial 2023: Palm Oil Foods Highlights & Side Effects. Trial Name: NCT04975763 — N/A
Palm Oil Foods (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04975763 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are engaged in this clinical investigation?

"Affirmative. Clinicaltrials.gov confirms that this medical investigation, which was originally posted on July 19th 2021 is still recruiting participants. Currently, 16 patients must be recruited from a single site for the trial to continue as planned."

Answered by AI

Are any new participants being enrolled in this medical trial currently?

"From the data listed on clinicaltrials.gov, this trial is actively looking to enrol patients - with its initial posting dating back to July 19th 2021 and most recent editing occurring on September 19th 2022."

Answered by AI

Is it feasible to participate in this research trial?

"Herein, we are looking for 16 test subjects with a BMI between 25 and 55 kg/m2 who have not smoked in the last year. The age range is from 25 to 80 years old."

Answered by AI

Is the trial open to individuals aged 50 and above?

"This medical trial seeks individuals between the ages of 25 and 80."

Answered by AI
~4 spots leftby Mar 2025