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Diagnostic Procedures for Asthma
Study Summary
This trial is looking for airway inflammation factors and whether they are linked to atopy and asthma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- You have a positive skin-prick test reaction to a specific allergen at a certain concentration.You are likely to not follow the study rules well.Your lung function test shows that you can breathe out at least 75% of what is expected for someone your age and size.I am pregnant, not using birth control, trying to get pregnant, or breastfeeding.You have a history of allergies to cats, dust mites, or seasonal allergies.You have a positive allergy test for cat dander or dust mite allergens.I am willing to talk with the lead researcher.I haven't taken antibiotics for lung issues in the last month or had a lung infection in the last 6 weeks.I have a history of blood clotting issues or I am on blood thinners.I am between 18 and 50 years old.You have a methacholine PC20 level less than 16 mg/ml.I have never smoked or have smoked less than 5 pack-years in my life.I am taking certain medications.I have been using Xolair for 6 months.I have a history of allergies, asthma, or nasal/sinus issues.You have a history of allergic reactions to cats or dust mites, and have shown a positive skin reaction to allergen tests.I have had an asthma attack or signs of a respiratory infection in the last 6 weeks.I have been intubated due to severe asthma in the past.I haven't smoked cigarettes in the last 5 years and have smoked less than 10 pack-years in total.I have a lung condition other than cancer.I have received immunotherapy for cat or dust mite allergies.I have specific health conditions.I am currently taking prescribed medications.You are regularly around second-hand cigarette smoke or indoor pets, except for dogs. If you have a dog, you must not be allergic to it and must have a negative skin test for dog allergies.You cannot tolerate certain medications.Your lung function tests show that your breathing is at least 90% of what is expected for someone your age and size.
- Group 1: allergic asthmatic, allergic nonasthmatic, healthy
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what extent have Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage been scrutinized in other scientific research?
"Presently, there is one active trial for Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage with zero studies in Phase 3. This medical investigation can be accessed at one location located within the city of Boston, Massachusetts."
Does the protocol for this experiment extend to individuals over 55 years of age?
"To qualify for this research, individuals must be between 18 and 50 years of age. 113 studies are available to those younger than 18 while people over 65 can access 198 trials that cater to their needs."
How many individuals can participate in this clinical experiment?
"Absolutely. Clinicaltrials.gov reveals that this medical trial is actively recruiting 313 eligible patients, with the initial posting dating back to January 1st 2008 and the last update being on April 4th 2022 from one single location."
Who is eligible to apply for participation in this research project?
"This clinical trial is recruiting 313 asthma patients ranging from 18 to 50 years old. Eligible participants must possess a FEV1 of no less than 75% the predicted value, demonstrate skin reactivity for cat or dust mite allergen through positive test results, have abstained from smoking for at least 5 years (defined as under 5 pack-years lifetime), be capable of providing informed consent and willing to partake in an interview with the principal investigator."
Has the Federal Drug Administration (FDA) sanctioned Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage?
"A score of 1 was given to Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage due to the limited evidence in support of its safety efficacy profile."
Is this experiment still in the process of recruiting participants?
"As indicated on clinicaltrials.gov, this trial is open for patient enrollment and has been since January 1st of 2008. The record was last updated on April 4th 2022."
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