Paracaine

Local Anaesthesia therapy

Treatment

0 Active Studies for Paracaine

Treatment for

Local Anaesthesia therapy

What is Paracaine

ProparacaineThe Generic name of this drug

Treatment SummaryProparacaine is a local anesthetic used to numb the surface of the eye. It is applied as an ophthalmic solution at a concentration of 0.5% in the form of hydrochloride salt.

Alcaineis the brand name

Paracaine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Alcaine

Proparacaine

1973

Effectiveness

How Paracaine Affects PatientsProparacaine works by blocking the flow of ions that cause nerve impulses, numbing the area it is applied to. It does this by binding to and blocking the action of certain sodium channels.

How Paracaine works in the bodyProparacaine works by limiting sodium's ability to pass through the nerve cell membrane. It does this by interacting with the protein residues that make up the cell membrane, effectively blocking the necessary changes that create an action potential. We don't know exactly how it works, but this is the most likely explanation.

When to interrupt dosage

The measure of Paracaine is contingent upon the diagnosed case. The amount of dosage may differ, as per the approach of delivery (e.g. Ophthalmic or Solution / drops) listed in the table below.

Condition

Dosage

Administration

Local Anaesthesia therapy

, 5.0 mg/mL, 0.5 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ophthalmic; Topical, Solution - Ophthalmic; Topical

Warnings

There are 4 known major drug interactions with Paracaine.

Common Paracaine Drug Interactions

Drug Name

Risk Level

Description

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Proparacaine is combined with Oliceridine.

Daridorexant

Minor

The risk or severity of CNS depression can be increased when Proparacaine is combined with Daridorexant.

Fluoxetine

Moderate

Proparacaine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.

Ziprasidone

Moderate

The risk or severity of adverse effects can be increased when Proparacaine is combined with Ziprasidone.

Paracaine Novel Uses: Which Conditions Have a Clinical Trial Featuring Paracaine?

No active studies are currently exploring the potential of Paracaine in providing Local Anesthesia.

Condition

Clinical Trials

Trial Phases

Local Anaesthesia therapy

0 Actively Recruiting

Paracaine Reviews: What are patients saying about Paracaine?

4Patient Review

1/12/2009

Paracaine for Anesthesia of the Cornea of the Eye

1Patient Review

7/31/2009

Paracaine for Local Anesthesia for Eye Surgery

I had an severe allergic reaction when this medication was applied to my eye. It caused sweating, chills, vomiting, and diarrhea.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about paracaine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class of drug is proparacaine?

"Proparacaine is a type of local anesthetic that works quickly."

Answered by AI

What is proparacaine used for?

"The Proparacaine eye drops work by numbing the eye to prevent pain during surgery, certain tests, or procedures. The drops block the pain signals at the nerve endings in the eye."

Answered by AI

How often can you use proparacaine eye drops?

"Your provider will give you 1 drop of proparacaine (Alcaine) every 5 to 10 minutes for up to 5 to 7 doses for short procedures on the eye. You won't be able to take any more because the medication is only for short-term use."

Answered by AI

Can humans use proparacaine?

"The long-term side effects of Proparacaine are unknown; prolonged use may possibly delay wound healing. Proparacaine should be used cautiously and sparingly in patients with known allergies, cardiac disease, or hyperthyroidism."

Answered by AI