Monistat 3

Inflammation, Tinea Pedis, Dermatophytosis + 20 more

Treatment

20 Active Studies for Monistat 3

What is Monistat 3

Miconazole

The Generic name of this drug

Treatment Summary

Miconazole is an antifungal medication used to treat yeast infections of the mouth and vagina. It also has some activity against certain types of bacteria. It is available as a variety of products, including suppositories, creams, gels, and tablets. Miconazole works by inhibiting the activity of a fungal enzyme called CYP450 14α-lanosterol demethylase. It was first approved by the FDA in 1974 and is still used today. Resistance to miconazole is relatively rare.

SUNMARK MICONAZOLE NITRATE antifungal

is the brand name

Monistat 3 Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

SUNMARK MICONAZOLE NITRATE antifungal

Miconazole

1991

255

Effectiveness

How Monistat 3 Affects Patients

Miconazole is an antifungal medication that works by blocking an enzyme in the body. It is usually applied directly to the skin, and very little of it enters the bloodstream. Most people do not have side effects, but some may experience allergic reactions or anaphylaxis. People using this medication vaginally should not rely on birth control or tampons to prevent pregnancy or infection.

How Monistat 3 works in the body

Miconazole works in three main ways to fight fungal infections caused by Candida. Firstly, it stops the fungus from making a protective covering that helps it survive. Secondly, it stimulates the production of chemicals within the cell that cause it to die. Lastly, it prevents the fungus from forming biofilms, which are resistant to antibiotics. It does this by stopping the fungus from changing into its more resilient form.

When to interrupt dosage

The suggested dosage of Monistat 3 is contingent upon the identified condition, including Gastrointestinal candidiasis, Nail candida and Infection, Mixed. The quantity of dosage is itemized in the table below, contingent upon the method of administration (e.g. Topical or Aerosol, spray - Topical).

Condition

Dosage

Administration

Candidiasis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Oropharyngeal Candidiasis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Yeast Infection

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Dermatitis, Seborrheic

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Tinea

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Acne Vulgaris

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Inflammation

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Tinea Pedis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Dermatophytosis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Arthrodermataceae

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

cutaneous candidiasis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Candidiasis, Vulvovaginal

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Tinea Cruris

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Ringworm

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Dermatitis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Onychomycosis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Cellulitis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Coinfection

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Hyperhidrosis

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Intertrigo

, 0.02 mg/mg, 0.0206 mg/mg, 0.1 mg, 20.0 mg/mL, 0.002 mg/mg, 0.026 mg/mg, 0.04 mg/mg, 0.00002 mg/mg, 0.142 mg/mg, 0.0002 mg/mg, 200.0 mg/mg, 0.03 mg/mg, 0.013 mg/mg, 0.07 mg/mg, 0.0256 mg/mg, 0.02 mL/mL, 50.0 mg, 2.0 %, 400.0 mg, 1200.0 mg, 4.0 %, 100.0 mg, 0.03 mg/mL, 0.0025 mg/mg, 0.112 mg/mg, 0.0282 mg/mg, 200.0 mg, 0.02 mg/mL, 20.0 mg/mg, 40.0 mg, 0.1 mg/mg, 100.0 mg/mg, 0.06 mg/mg, 2.0 mg/mg, 0.2 mg/mg, 0.17 mg/mg

, Powder, Powder - Topical, Topical, Kit, Cream - Topical, Spray, Spray - Topical, Vaginal, Cream - Vaginal, Suppository - Vaginal, Tincture, Tincture - Topical, Kit - Vaginal, Ointment, Ointment - Topical, Liquid, Liquid - Topical, Cream, Aerosol, spray, Aerosol, spray - Topical, Aerosol, powder - Topical, Aerosol, powder, Tablet, Tablet - Buccal, Buccal, Insert, Suppository, Aerosol, Aerosol - Topical, Capsule; Cream; Kit, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Cream; Insert, Cream; Suppository, Topical; Vaginal, Kit - Topical; Vaginal, Lotion, Lotion - Topical, Insert - Vaginal, Cream; Insert - Topical; Vaginal, Cream; Suppository - Topical; Vaginal, Paste, Paste - Topical, Kit - Topical

Warnings

Monistat 3 has two counter-indications and should not be taken when encountering the conditions in the following table.

Monistat 3 Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Miconazole may interact with Pulse Frequency

There are 20 known major drug interactions with Monistat 3.

Common Monistat 3 Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Miconazole.

Abrocitinib

Major

The metabolism of Abrocitinib can be decreased when combined with Miconazole.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Miconazole.

Acetylsalicylic acid

Major

The metabolism of Acetylsalicylic acid can be decreased when combined with Miconazole.

Albendazole

Major

The metabolism of Albendazole can be decreased when combined with Miconazole.

Monistat 3 Toxicity & Overdose Risk

Taking too much miconazole can lead to serious side effects like headaches, skin irritation, diarrhea, nausea, vomiting, stomach pain, and a strange taste in the mouth. If you overdose on miconazole, seek medical attention and take symptomatic and supportive measures. In rats, the lowest dose of miconazole that has been known to be toxic is 500mg/kg.

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Monistat 3 Novel Uses: Which Conditions Have a Clinical Trial Featuring Monistat 3?

203 active trials are analyzing the potential of Monistat 3 to provide relief from Dermatophytosis, Inflammation, Hyperhidrosis and Body Odor.

Condition

Clinical Trials

Trial Phases

Inflammation

57 Actively Recruiting

Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4

Yeast Infection

0 Actively Recruiting

Onychomycosis

0 Actively Recruiting

Acne Vulgaris

2 Actively Recruiting

Phase 1, Phase 2, Early Phase 1

Candidiasis

0 Actively Recruiting

Dermatitis, Seborrheic

0 Actively Recruiting

Dermatophytosis

0 Actively Recruiting

cutaneous candidiasis

0 Actively Recruiting

Cellulitis

0 Actively Recruiting

Tinea Versicolor

0 Actively Recruiting

Skin candida

0 Actively Recruiting

Tinea Pedis

0 Actively Recruiting

Arthrodermataceae

0 Actively Recruiting

Kerion Celsi

0 Actively Recruiting

Candidiasis, Vulvovaginal

0 Actively Recruiting

Tinea Cruris

0 Actively Recruiting

Tinea

0 Actively Recruiting

Intertrigo

0 Actively Recruiting

Oropharyngeal Candidiasis

0 Actively Recruiting

Ringworm

0 Actively Recruiting

Monistat 3 Reviews: What are patients saying about Monistat 3?

5

Patient Review

8/13/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

Monistat 3 day worked great for me! I followed the instructions and inserted it before bed. The redness went away after the first dose, and the swelling and itching after the second. I felt 100% better and took the third dose as a precautionary measure. I would highly recommend this product to anyone experiencing similar issues.

5

Patient Review

8/13/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

Monistat definitely addressed the redness I was dealing with, and it didn't even take the full three days!

4

Patient Review

7/1/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

This treatment really works. I've experienced many yeast infections over the years and this medication has worked for me just as well as a pill from the doctor. I've even had my doctor recommend Monistat to me when the pill didn't work. There is some uncomfortable itching and the annoyance of having to wear a liner because of discharge, but it beats a yeast infection.

4

Patient Review

7/1/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

Monistat has been just as effective for me as a pill from the doctor, if not more so. I've even had my doctor recommend it to me in the past when other treatments haven't worked. The itching can be a bit uncomfortable and there's also the discharge to deal with, but it's still preferable to a yeast infection.

3.3

Patient Review

10/22/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

While this did work for me, it was quite painful to apply. I would recommend getting a diagnosis first if possible, as some other treatments may be more effective depending on the cause of your infection.

3.3

Patient Review

5/23/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

Before I got monistat 3, I had small indications that I had a yeast infection: a little itch and burn, and white heavy discharge. So, on day 1 of monistat insertion with a rub of the ointment, I was in so much agony. I felt itchy and hurting. My bf was my support and I have my weed card so I smoked too but it lasted like 2 or 3 hours then the 2nd painful irritation after insertion was unbearable for 2 hours then the 3rd day of insertion went through unbearable irritation for an hour ...

3.3

Patient Review

10/22/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

If you have sensitive skin, this might cause some burning. But if you've been diagnosed with a yeast infection, it's worth trying as other treatments haven't worked for me in the past.

3.3

Patient Review

5/23/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

The insertion process was more painful than I anticipated, but the results were worth it.

2.3

Patient Review

8/28/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

The first ovule worked as it should have, but the next two were incredibly hard. I had to peel off the outer shell and hold it under hot water until it was soft enough to use. This seems like a safety concern since it could take longer to dissolve than intended.

2.3

Patient Review

8/28/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

Two of the ovules were really hard. The first one worked right, dissolved immediately, but after that it was so hard, I didn't even try to use it that way again. I held it under hot water until I could peel off the outer shell and then it was fine. I doubt whatever that is made of is safe since it could harden and possibly take longer to dissolve than was intended.

2

Patient Review

10/22/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I've used the 7 day treatment before with no issues, but this 3 day version caused burning and itching. I won't be using it again!

2

Patient Review

10/22/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I’ve used the 7 day treatment in the past with no issues. This is the first time I’ve used the 3 day treatment. It has caused severe burning and itching. I’ll never use the 3 day again!

1.3

Patient Review

3/18/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I made the mistake of not reading the reviews before purchasing this product and I am now regretting it. I am up in the middle of the night with burning sensations, just like everyone else has mentioned. Save your money and go to the doctor instead.

1.3

Patient Review

3/18/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I made the mistake of not reading reviews before buying this, and now I'm up in the middle of the night with burning sensations. From what I can tell, it's not worth the money to buy this when you could just go to the doctor instead. Save your money for something more enjoyable, like ice cream!

1

Patient Review

9/19/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I've used this medication before and it worked great, but this time was the most pain I've ever experienced in my life. The burning and itching were unbearable. I got some relief after mixing it with Vagasil.

1

Patient Review

6/9/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I regret purchasing Monistat 3 from Walmart. Today is only day two of using it, and the pain is unbearable. I feel like there's hot grease in my vagina. Definitely do not recommend this product.

1

Patient Review

9/19/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

In the past, this medication has worked for me. This time around, however, it was incredibly painful and intense burning and itching. I got some relief after mixing it with Vagasil.

1

Patient Review

6/9/2022

Monistat 3 for Yeast Infection of Vagina and Vulva

I bought Monistat 3 from Walmart, and after using it today (day 2), I regret not just going to the doctor. The pain is unbearable. It feels like there's hot grease in my vagina. Definitely do not recommend.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about monistat 3

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Monistat 3 do?

"It works by stopping the growth of yeast (fungus) that causes the infection.

Miconazole is a medication used to treat vaginal yeast infections. It can reduce the burning, itching, and discharge that come with this condition. Miconazole is an azole antifungal medication, which means it works by stopping the growth of the yeast (fungus) that causes the infection."

Answered by AI

How long does it take for Monistat 3 to work?

"If you use MONISTAT® as directed, you may start to see a reduction in symptoms within a few hours. However, if your symptoms do not improve after three days, or if they worsen after seven days, this may be indicative of a more serious underlying condition."

Answered by AI

Does Monistat 3 cure yeast infection in 3 days?

"If you use MONISTAT® 3-Day Treatment Cream, you should see full clinical cure in 3 days."

Answered by AI

How long is Monistat 3 supposed to stay in?

"The MONISTAT® 3 products are designed to be taken over the course of three days, which is a great option for women who want a more consistent treatment with moderate dosage levels, as opposed to a single high-dose day."

Answered by AI

Clinical Trials for Monistat 3

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT

The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)

Waitlist Available
Has No Placebo

UConn Health

Cutter Lindbergh, Ph.D.

Image of Department of Nutritional Sciences in Storrs, United States.

Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT

The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.

Recruiting
Paid Trial

Department of Nutritional Sciences

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Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies

Phase 2
Recruiting

Abcentra Investigational Site (+6 Sites)

Abcentra

Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN

Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.

Recruiting
Has No Placebo

School of Public Health

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Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL

Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.

Recruiting
Online Trial

Tesla MedBed at Tampa-FL (+1 Sites)

James Z Liu, MD, PhD

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Moisturizers for Aging

65+
All Sexes
San Francisco, CA

This is a randomized, investigator-blinded, self-controlled pilot study of the physiologic response to topical moisturizers among older adults with dry skin. The overarching hypothesis is that skin barrier decline is an important source of chronic inflammation, and that skin barrier restoration with moisturizers can reduce serum biomarkers of inflammation. The primary objective is to determine the feasibility for a larger trial, and the secondary objectives are to determine the extent to which measures of serum inflammation, skin barrier function, and the skin microbiome change in response to moisturizers. Participants will be asked to apply one of two topical moisturizers that are widely available over the counter in the US (Vaseline® 100% pure petroleum jelly or CeraVe® moisturizing cream) once daily for 4 weeks to the front of the torso, buttocks, arms, and legs. Subjects will act as their own control (i.e. they will be asked to apply the study moisturizer they are randomized to for one intervention period (4 weeks) and not to apply topical moisturizers for the other 4- week intervention period). Participants will be randomized in a 1:1:1:1 ratio to one of 4 treatment groups: i. no intervention then CeraVe; ii. CeraVe then no intervention; iii. no intervention then Vaseline; iv. Vaseline then no intervention. At each visit (baseline, week 4, and week 8), participants will undergo skin barrier testing, skin microbiome sampling, and phlebotomy to measure serum inflammatory markers.

Phase 4
Recruiting

UCSF

Katrina Abuabara, MD

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