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What is Methylin Er
MethylphenidateThe Generic name of this drug
Treatment SummaryMethylphenidate is a stimulant medication used to treat Attention-Deficit/Hyperactivity Disorder (ADHD). It is sold under the brands Ritalin, Concerta, and Biphentin. Methylphenidate works by increasing levels of dopamine and norepinephrine in the brain, which can improve focus and reduce impulsivity in people with ADHD. Long-acting formulations of methylphenidate, like Concerta and Biphentin, are recommended for once-daily dosing and can provide up to 12 hours of symptom relief. While effective, methylphenidate carries a black box warning due to its potential for
Methylphenidate Hydrochlorideis the brand name
Methylin Er Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methylphenidate Hydrochloride
Methylphenidate
1955
490
Effectiveness
How Methylin Er Affects PatientsMethylphenidate is a combination of two different variations, the d- and l-isomers. The d-isomer is more powerful than the l-isomer, and binds to dopamine-rich areas in the brain, especially the prefrontal cortex. This area of the brain is important for ADHD and taking methylphenidate has been shown to increase activity and cause repetitive behaviors in certain animal models.
How Methylin Er works in the bodyMethylphenidate is thought to work by increasing the presence of norepinephrine and dopamine in the brain. It does this by blocking the reuptake of these neurotransmitters, which helps prolong their action. At lower doses, methylphenidate can improve cognitive function and reduce impulsivity, while higher doses can cause impaired cognition and increased movement. Methylphenidate also works by activating alpha-1 adrenergic receptors and by helping to overcome abnormalities in dopamine transporter and receptor genes.
When to interrupt dosage
The suggested dosage of Methylin Er is contingent upon the diagnosed condition. The quantity of dosage fluctuates, according to the technique of delivery specified in the table below.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release, Suspension, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Narcolepsy
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release, Suspension, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Warnings
Methylin Er has fourteen inhibitions and should not be united with any of the conditions mentioned in the subsequent table.Methylin Er ContraindicationsCondition
Risk Level
Notes
advanced arteriosclerosis
Do Not Combine
Gilles de la Tourette syndrome
Do Not Combine
Thyrotoxicosis
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
Hypertensive disease
Do Not Combine
Pulse Frequency
Do Not Combine
Tension
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Gilles de la Tourette's Syndrome
Do Not Combine
Pheochromocytomas
Do Not Combine
Tic, Motor
Do Not Combine
Agitation
Do Not Combine
Common Methylin Er Drug Interactions
Drug Name
Risk Level
Description
Desflurane
Major
Methylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Methylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Methylphenidate may increase the hypertensive activities of Enflurane.
Halothane
Major
Methylphenidate may increase the hypertensive activities of Halothane.
Isoflurane
Major
Methylphenidate may increase the hypertensive activities of Isoflurane.
Methylin Er Toxicity & Overdose RiskOverdosing on atropine can cause symptoms like nausea, trembling, increased reflexes, muscle twitching, seizures (which may be followed by a coma), feeling happy and confused, seeing and hearing things that aren't real, heavy sweating, flushing, headaches, high fever, rapid heartbeat, abnormal heart rhythms, high blood pressure, wide pupils, and dry mouth. The lowest dose of atropine that has been known to be fatal to mice is 190mg/kg when taken orally.
Methylin Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Methylin Er?
Currently, 84 active clinical trials are assessing the potential of Methylin Er to alleviate Attention Deficit Hyperactivity Disorder.Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Narcolepsy
10 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Methylin Er Reviews: What are patients saying about Methylin Er?
5Patient Review
12/3/2008 We've been using this medication for my son since he was six years old, and it's been working great. We have to adjust the dosage occasionally due to his growth, but that's to be expected.
5Patient Review
7/25/2010 I've been using this medication for depression and I'm feeling more energetic and optimistic after just one month. 40mg per day is the dosage I take, but that's something you should discuss with a professional who can monitor your reaction to the drug.
5Patient Review
9/15/2008 I appreciate how this medication is easy for my daughter to swallow, and that the dose is low so we can gradually increase it if needed. Being able to manage my child's ADD with this drug has made me much less anxious.
4.7Patient Review
6/21/2009 Methylin ER has been a godsend for my son. He was failing three classes when we first started using it, and now he's on the honor roll. It definitely helps him focus during school hours, though homework is still a bit of a struggle. The only downside is that he's gained 10 pounds in six weeks; he isn't hungry during the day, but then overeats at night.
4.7Patient Review
5/29/2014 I feel like this treatment has helped me to avoid outbursts of anger.
4.3Patient Review
11/2/2010 I've tried a lot of different treatments for my ADD, and this one is by far the best. It's affordable and it lasts a long time.
4Patient Review
10/16/2008 Though this ADD medication has been helpful for me in general, I experience concerning chest pains and faintness about once a month. My doctor downplayed my concerns, but it seems like a pretty big drawback to the otherwise positive effects of the drug.
4Patient Review
3/12/2010 I have found this treatment to be much less effective than adderall for my depression and ADD. I am also supposed to take it three times a day, which is difficult to remember in the middle of my workday.
3.3Patient Review
1/12/2012 This medication helped me to be more mindful and less impulsive.
2.3Patient Review
2/29/2008Patient Q&A Section about methylin er
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is methylphenidate ER the same as Adderall?
"Both Adderall and Ritalin are drugs that act as stimulants to the central nervous system, and are used to treat attention deficit hyperactivity disorder. Ritalin, however, is not an amphetamine, and its effects are generally less intense than those of Adderall."
Answered by AI
Is methylin the same as Adderall?
"Although Ritalin and Adderall are both stimulants, they have different active ingredients. Ritalin's active ingredient is methylphenidate hydrochloride, while Adderall is a combination of amphetamine and dextroamphetamine. Both medications are effective in reducing the symptoms of ADHD."
Answered by AI
Is methylphenidate ER the same as Ritalin?
"The drug methylphenidate is available in several different forms, under brand names such as Ritalin, Ritalin SR, and Ritalin LA."
Answered by AI
Is methylin the same as Concerta?
"Concerta and Ritalin are both stimulant medications used to treat ADHD. A recent meta-analysis found that methylphenidate hydrochloride (MPH) is the most effective first-line treatment for children with ADHD."
Answered by AI