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What is Jatenzo
Testosterone undecanoateThe Generic name of this drug
Treatment SummaryTestosterone undecanoate is a medication used to treat testosterone deficiency. It is available as an intramuscular injection and as an oral capsule. Testosterone undecanoate can only be prescribed to treat conditions related to low testosterone caused by structural or genetic factors and cannot be used to treat age-related testosterone deficiency.
Aveedis the brand name
Jatenzo Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Aveed
Testosterone undecanoate
2014
8
Effectiveness
How Jatenzo Affects PatientsTestosterone undecanoate, when taken as a hormone replacement therapy, is a type of medicine that provides an outside source of testosterone for males with low testosterone levels. Testosterone is an important hormone involved in male sexual development and other functions. However, it is a controlled substance in the US because it can be abused by athletes and bodybuilders. Taking too much testosterone can lead to withdrawal symptoms such as depression, fatigue, and decreased libido. In women, taking testosterone can cause extra body hair, a deeper voice, breast shrinkage, male-pattern baldness, and menstrual irregularities. In adolescents, taking testosterone can stop growth and
How Jatenzo works in the bodyTestosterone is an important hormone in the body that helps maintain the physical characteristics of males. Low levels of testosterone, known as hypogonadism, can be caused by problems with the gonads or with the hypothalamus or pituitary glands. Testosterone undecanoate is changed by the body into testosterone, which is the active component of the compound. Testosterone can be further converted into a more powerful form called dihydrotestosterone. This hormone binds to receptors in the bones, muscles, prostate, and fat tissues and helps regulate these areas. Testosterone can help improve sexual function, increase muscle mass, improve bone
When to interrupt dosage
The suggested measure of Jatenzo is contingent upon the diagnosed condition, for instance Testosterone Deficiency, Hypergonadotropic Hypogonadism and Hypogonadotropic hypogonadism. The dosage amounts differ, in line with the technique of delivery (e.g. Oral or Capsule, liquid filled - Oral) noted in the accompanying table.Condition
Dosage
Administration
Hypogonadotropic hypogonadism
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Testosterone Deficiency
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Hypergonadotropic Hypogonadism
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Hormone Replacement Therapy
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Warnings
Jatenzo has four contraindications, so it should not be ingested when encountering any of the conditions provided in the subsequent table.Jatenzo ContraindicationsCondition
Risk Level
Notes
Breast Cancer
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Testosterone Undecanoate may interact with Pulse Frequency
Hypogonadism
Do Not Combine
Prostate Cancer
Do Not Combine
Common Jatenzo Drug Interactions
Drug Name
Risk Level
Description
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone undecanoate.
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Testosterone undecanoate.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Testosterone undecanoate.
Lumateperone
Major
The serum concentration of Lumateperone can be decreased when it is combined with Testosterone undecanoate.
Ranolazine
Major
The metabolism of Ranolazine can be increased when combined with Testosterone undecanoate.
Jatenzo Toxicity & Overdose RiskThe toxic dose of testosterone undecanoate in mice and rats is 4000mg/kg when taken orally and 2880mg/kg when taken subcutaneously. Taking a 20% higher dose than the recommended dose has not caused any adverse reactions. Signs of an overdose include discontinuation of the drug, heart attack, stroke, liver damage, mental health issues including depression, mania, and aggression, and decreased fertility in men.
Jatenzo Novel Uses: Which Conditions Have a Clinical Trial Featuring Jatenzo?
At present, four active trials are examining the potential of Jatenzo to mitigate Hypergonadotropic Hypogonadism, Hypogonadotropic Hypogonadism and Testosterone Deficiency.Condition
Clinical Trials
Trial Phases
Hypogonadotropic hypogonadism
0 Actively Recruiting
Hypergonadotropic Hypogonadism
0 Actively Recruiting
Hormone Replacement Therapy
0 Actively Recruiting
Testosterone Deficiency
3 Actively Recruiting
Phase 2, Phase 4
Patient Q&A Section about jatenzo
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does Jatenzo cause hair loss?
"You may experience nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, or acne."
Answered by AI
Is Jatenzo a steroid?
"Jatenzo is a type of medication known as an androgen and anabolic steroid."
Answered by AI
How much testosterone is in Jatenzo?
"Jatenzo is a medication used to replace testosterone levels in men. It is available in capsule form in three different strengths. Jatenzo may also be referred to as a "testosterone booster.""
Answered by AI
What is Jatenzo used for?
"JATENZO is a prescription drug that contains testosterone and is used to treat adult men who have low or no testosterone due to certain medical conditions. JATENZO is a controlled substance (CIII) because it contains testosterone, which can be a target for people who abuse prescription drugs."
Answered by AI