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What is Pimtrea
EthinylestradiolThe Generic name of this drug
Treatment SummaryEthinylestradiol was developed in 1938 by two scientists, Hans Herloff Inhoffen and Walter Hohlweg, at Schering. The drug was designed to be more easily absorbed into the body than other estrogens. It quickly replaced mestranol in contraceptive pills and was approved by the FDA in 1943.
LOESTRIN Fe 1.5/30is the brand name
Pimtrea Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
LOESTRIN Fe 1.5/30
Ethinylestradiol
1973
679
Approved as Treatment by the FDA
Ethinylestradiol, also known as LOESTRIN Fe 1.5/30, is approved by the FDA for 1 uses including Birth Control .Birth Control
Used to treat Contraception in combination with Levonorgestrel
Effectiveness
How Pimtrea Affects PatientsEthinylestradiol is a synthetic form of the female hormone estrogen. It works by reducing the amount of luteinizing hormone and gonadotrophic hormone in the body, which stops ovulation and makes it more difficult for a fertilized egg to attach to the uterus. It is taken once a day and is considered a safe drug, although there is still a risk of developing thrombotic events.
How Pimtrea works in the bodyEthinylestradiol is a synthetic estrogen. It affects the body by reducing bone density, suppressing ovulation, and thickening cervical mucus. It also stops the endometrium from changing so a fertilized egg cannot attach itself. Ethinylestradiol decreases luteinizing hormone to reduce blood flow in the endometrium, and increases sex hormone binding globulin.
When to interrupt dosage
The advised measure of Pimtrea is contingent upon the diagnosed condition, such as Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The amount of dosage fluctuates, as per the administration system outlined in the table below.Condition
Dosage
Administration
Birth Control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Mild to Moderate Acne
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopausal Osteoporosis
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Patient desires oral contraception for birth control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Acne Vulgaris
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Folate supplementation therapy
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Hormonal Contraception
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopause
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Warnings
Pimtrea has twenty-six contraindications and should not be taken in combination with the ailments specified in the subsequent table.Pimtrea ContraindicationsCondition
Risk Level
Notes
Heavy Smoking
Do Not Combine
Metrorrhagia
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Thrombophlebitis
Do Not Combine
high risk of venous thrombotic disease
Do Not Combine
history of deep venous thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
Breast
Do Not Combine
Coronary Artery Disease
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Thromboembolism
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Hypersensitivity
Do Not Combine
Pulse Frequency
Do Not Combine
Adrenal Insufficiency
Do Not Combine
major surgery with prolonged immobilization
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypertension
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast Cancer
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
Deep Vein Thrombosis
Do Not Combine
Decompensated Cirrhosis
Do Not Combine
Breast
Do Not Combine
Impaired Renal Function
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ethinylestradiol may interact with Pulse Frequency
Common Pimtrea Drug Interactions
Drug Name
Risk Level
Description
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Ethinylestradiol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Ethinylestradiol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Ethinylestradiol.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Ethinylestradiol.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Ethinylestradiol.
Pimtrea Toxicity & Overdose RiskWomen who overdose on birth control may experience bleeding, nausea, vomiting, breast tenderness, abdominal pain, drowsiness, and fatigue. Treatment for overdose should include monitoring of potassium, sodium, and acid levels in the blood, as well as providing supportive care.
Pimtrea Novel Uses: Which Conditions Have a Clinical Trial Featuring Pimtrea?
38 active clinical trials are currently evaluating the capacity of Pimtrea to provide Folate supplementation therapy, alleviate Premenstrual Dysphoric Disorder and reduce the symptoms of Menopause.Condition
Clinical Trials
Trial Phases
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Patient desires oral contraception for birth control
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
Mild to Moderate Acne
0 Actively Recruiting
Menopausal Osteoporosis
0 Actively Recruiting
Menopause
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Pimtrea Reviews: What are patients saying about Pimtrea?
5Patient Review
7/6/2017 I started using this birth control shortly before my 20th birthday and have been extremely pleased with it. My periods are lighter and I haven't fainted or had cramps since being on the pill. I also haven't gained weight, which is a huge plus.
5Patient Review
1/24/2015 So far, so good with this prescription. I didn't experience any negative side effects, which is what I expected given that it's essentially the same drug as my previous one (just with a different name and appearance).
5Patient Review
1/5/20154Patient Review
3/25/2015 My doctor prescribed this because I had taken a birth control in the past that made me experience severe breakthrough bleeding and I simply can not handle that. Also, worried about gaining weight. So far, I have been pretty satisfied - I have had an increase in discharge and it can be slightly pink tinted in nature but I'll deal with that over bleeding any day. I might be slightly more moody but overall, very pleased.
2.7Patient Review
5/6/2015 I switched to Pimtrea from Kariva about a month ago, and I haven't been pleased. My period has been going on for four weeks now with no sign of stopping. My acne has gotten worse, I feel bloated, and I've gained weight around my stomach. The bleeding is pretty heavy too. I start my second pack in 2 days, so hopefully it will get better or else I'll have to switch birth controls again.
2.7Patient Review
8/13/2015 I was given this as a replacement for Kariva 1 1/2 weeks ago. For me, this is not an acceptable switch. My vision has been blurry, my blood pressure has gone up, I have had severe bloating, breakthrough bleeding, and numerous panic attacks. I called my pharmacy to get it replaced immediately and to make sure they never give me this again.
1.7Patient Review
1/28/2015 I've been taking Pimtrea for a few months now and I can say that it's given me nothing but problems. From the side effects, to increased acne, to an unsightly rash on my chest - this drug has done nothing but harm me. I'm switching to another brand of birth control as soon as possible.
Patient Q&A Section about pimtrea
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Pimtrea generic for?
"Pimtrea is a drug taken orally that is used as a contraceptive to prevent pregnancy. It is available in generic form."
Answered by AI
What are the green pills in Pimtrea?
"Pimtreaâ„¢ is a combination of two different types of birth control pills; desogestrel/ethinyl estradiol and ethinyl estradiol. The difference between the two pills is that the combination pill has 0.02 mg of ethinyl estradiol while the green pill has 0.01 mg. Ethinyl estradiol is absorbed quickly and almost completely."
Answered by AI
Is Pimtrea a combination pill?
"Pimtrea is a combination birth control pill that uses female hormones to prevent ovulation. It also makes changes to your cervical mucus and uterine lining, making it more difficult for sperm to reach the uterus and for a fertilized egg to attach to it."
Answered by AI
Is Pimtrea progestin only?
"The contraceptive pill contains two hormones: desogestrel, a progestin, and ethinyl estradiol, an estrogen."
Answered by AI